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Official Full Name endoplasmic reticulum lectin 1
Background This gene encodes a resident endoplasmic reticulum (ER) protein that functions in N-glycan recognition. This protein is thought to be involved in ER-associated degradation via its interaction with the membrane-associated ubiquitin ligase complex. It also functions as a regulator of multiple cellular stress-response pathways in a manner that promotes metastatic cell survival. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 21.
Synonyms ERLEC1; endoplasmic reticulum lectin 1; C2orf30, chromosome 2 open reading frame 30; CL25084; ERLECTIN; erlectin 1; XTP3 B; XTP3TPB; C2orf30; CL24936; CL2508; ER lectin; RP23 20N14.5; XTP3 transactivated gene B protein; XTP3 transactivated protein B; XTP3B; XTP3-transactivated protein B; XTP3-transactivated gene B protein; cancer invasion and metastasis-related; CIM; XTP3-B
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ERLEC1-1463H Recombinant Human ERLEC1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ERLEC1-6552HCL Recombinant Human ERLEC1 293 Cell Lysate HEK293 N/A
    Mouse Erlec1-2861M Recombinant Mouse Erlec1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse ERLEC1-5304M Recombinant Mouse ERLEC1 Protein Mammalian Cell His
    Rhesus Macaque ERLEC1-1493R Recombinant Rhesus monkey ERLEC1 Protein, His-tagged Mammalian Cell His
    Zebrafish ERLEC1-9918Z Recombinant Zebrafish ERLEC1 Mammalian Cell His

    ERLEC1 involved in several pathways and played different roles in them. We selected most pathways ERLEC1 participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with ERLEC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Protein processing in endoplasmic reticulum RAD23B; SVIP; CAPN2A; PDIP5; SAR1A; RAD23A; AMFR; DERL1; UFD1L; MBTPS2

    ERLEC1 has several biochemical functions, for example, glycoprotein binding, protein binding, unfolded protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ERLEC1 itself. We selected most functions ERLEC1 had, and list some proteins which have the same functions with ERLEC1. You can find most of the proteins on our site.

    Function Related Protein
    glycoprotein binding FOXRED2; Serpina1c; RGMA; BMPR1B; DNAJA2; IDE; PLAT; FBXO17; LDLR; LRRK2
    protein binding GSTM5; SF3B3; TJP2; SEMA6A; MBP; RAB32; RABGEF1; DNTT; HSD17B14; ZKSCAN1
    unfolded protein binding HSP90AA1; CALRL2; TOR1A; CRYABB; HSPA6; PDRG1; CCT8; SYVN1; UGGT1; CCT4

    ERLEC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ERLEC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ERLEC1.

    env; env; GH1; TNFRSF1A; STK11; Ncstn; Sel1l

    Dizaji, NB; Basseri, HR; et al. Molecular characterization of calreticulin from Anopheles stephensi midgut cells and functional assay of the recombinant calreticulin with Plasmodium berghei ookinetes. GENE 550:245-252(2014).
    Hong, D; Bai, YP; et al. Ox-LDL induces endothelial cell apoptosis via the LOX-1-dependent endoplasmic reticulum stress pathway. ATHEROSCLEROSIS 235:310-317(2014).

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