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Official Full Name family with sequence similarity 134, member B
Background The protein encoded by this gene is a cis-Golgi transmembrane protein that may be necessary for the long-term survival of nociceptive and autonomic ganglion neurons. Mutations in this gene are a cause of hereditary sensory and autonomic neuropathy type IIB (HSAN IIB), and this gene may also play a role in susceptibility to vascular dementia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms FAM134B; family with sequence similarity 134, member B; protein FAM134B; FLJ20152; F134B_HUMAN; JK1; JK-1
    • Species :
    • Human
    • Rat
    • Rhesus Macaque
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FAM134B-6426HCL Recombinant Human FAM134B 293 Cell Lysate HEK293 N/A
    Rat FAM134B-2219R Recombinant Rat FAM134B Protein Mammalian Cell His
    Rhesus Macaque FAM134B-1570R Recombinant Rhesus monkey FAM134B Protein, His-tagged Mammalian Cell His

    fam134b involved in several pathways and played different roles in them. We selected most pathways fam134b participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with fam134b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    fam134b has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by fam134b itself. We selected most functions fam134b had, and list some proteins which have the same functions with fam134b. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CEP68; NFYC; GRAP2; PIAS1; MBD3; SMARCC2; MTSS1; CHN2; G3BP2; SH3BP1

    fam134b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with fam134b here. Most of them are supplied by our site. Hope this information will be useful for your research of fam134b.


    Yuan, ZQ; Song, DG; et al. The novel gene pFAM134B positively regulates fat deposition in the subcutaneous fat of Sus scrofa. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 454:554-559(2014).
    Kasem, K; Gopalan, V; et al. JK1 (FAM134B) gene and colorectal cancer: A pilot study on the gene copy number alterations and correlations with clinicopathological parameters. EXPERIMENTAL AND MOLECULAR PATHOLOGY 97:31-36(2014).

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