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FARSA

  • Official Full Name

    phenylalanyl-tRNA synthetase, alpha subunit

  • Overview

    Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. This gene encodes a;product which is similar to the catalytic subunit of prokaryotic and Saccharomyces cerevisiae phenylalanyl-tRNA;synthetases (PheRS). This gene product has been shown to be expressed in a tumor-selective and cell cycle stage- and;differentiation-dependent manner, the first member of the tRNA synthetase gene family shown to exhibit this type of;regulated expression.
  • Synonyms

    FARSA; phenylalanyl-tRNA synthetase, alpha subunit; FARSL, FARSLA, phenylalanine tRNA synthetase like , phenylalanyl tRNA synthetase like, alpha subunit; phenylalanyl-tRNA synthetase alpha chain; CML33; phenylalanine tRNA ligase 1; alpha; cytoplasmic; CML 33; FARS; FARSL; FRSA; PheHA; Phenylalanine tRNA ligase 1 alpha cytoplasmic; Phenylalanine tRNA ligase alpha chain; Phenylalanine tRNA synthetase alpha subunit; Phenylalanine tRNA synthetase like alpha subunit; Phenylalanyl tRNA synthetase alpha chain; Phenylalanyl tRNA synthetase alpha subunit; Phenylalanyl tRNA synthetase like alpha subunit; PheRS; phenylalanine--tRNA ligase alpha chain; phenylalanine-tRNA synthetase alpha-subunit; phenylalanine tRNA ligase 1, alpha, cytoplasmic; phenylalanyl-tRNA synthetase-like, alpha subunit; phenylalanine-tRNA synthetas; FARSLA;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FARSA-3846H Recombinant Human FARSA Protein, GST-tagged Wheat Germ GST
Human FARSA-6326HCL Recombinant Human FARSA 293 Cell Lysate HEK293 N/A
Human FARSA-1170H Recombinant Human FARSA Protein (2-508 aa), His-SUMO-tagged E.coli His/SUMO 2-508 aa
Human FARSA-4759HF Recombinant Full Length Human FARSA Protein, GST-tagged In Vitro Cell Free System GST 508 amino acids
Human FARSA-1460H Recombinant Human FARSA Protein, His-tagged E.coli N-His Ala2-Ala283
Mouse FARSA-5683M Recombinant Mouse FARSA Protein Mammalian Cell His
Mouse FARSA-3119M-B Recombinant Mouse FARSA Protein Pre-coupled Magnetic Beads HEK293
Mouse FARSA-3119M Recombinant Mouse FARSA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque FARSA-1643R Recombinant Rhesus monkey FARSA Protein, His-tagged Mammalian Cell His
Rhesus Macaque FARSA-1467R-B Recombinant Rhesus Macaque FARSA Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque FARSA-1467R Recombinant Rhesus Macaque FARSA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish FARSA-4286Z Recombinant Zebrafish FARSA Mammalian Cell His
Chicken FARSA-4664C Recombinant Chicken FARSA Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FARSA Related Articles

FARSA involved in several pathways and played different roles in them. We selected most pathways FARSA participated on our site, such as Aminoacyl-tRNA biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with FARSA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Aminoacyl-tRNA biosynthesisGARS;MARS2;RARS2;SARS2;FARSA;FARS2;QRSL1;TARS;HARS2

FARSA has several biochemical functions, for example, ATP binding, phenylalanine-tRNA ligase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FARSA itself. We selected most functions FARSA had, and list some proteins which have the same functions with FARSA. You can find most of the proteins on our site.

Function Related Protein
ATP bindingTTLL10;PSMC4;DGKE;TWF2;PNKP;ABCB6A;YARS2;PARS2;KLHL8
phenylalanine-tRNA ligase activityFDXACB1;FARSB;FARSA;FARS2
poly(A) RNA bindingTOP2A;COX4I2;EXOSC9;NSUN2;NUPL2;CPSF7;DHX38;NPM3;MYEF2
protein bindingZNF207;SDC2;MCRS1;TSN;DGKZ;POLR3C;ITGA1;FES;DVL1
tRNA bindingMETTL1;PSTK;CTU1;MADD;RPL35A;EIF2A;FARS2;PTCD1;DARS2

FARSA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FARSA here. Most of them are supplied by our site. Hope this information will be useful for your research of FARSA.

ABI3; ECSIT; a8k1f4_human; USP11; PSMD2; USP32; HNRNPR; A2M; TDGF1; GORAB; XRCC3; EIF2AK2; LRRK2; Unc93b1

Miyazaki, K; et al. Molecular engineering of a PheS counterselection marker for improved operating efficiency in Escherichia coli. BIOTECHNIQUES 58:86-88(2015).
Ponmani, T; Munavar, MH; et al. G(673) could be a novel mutational hot spot for intragenic suppressors of pheS5 lesion in Escherichia coli. MICROBIOLOGYOPEN 3:369-382(2014).
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