|Official Full Name||fibulin 1|
|Background||Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3 end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants.|
|Synonyms||FBLN1; fibulin 1; fibulin-1; FBLN; Basement membrane protein 90; BM 90; FBLN1_HUMAN; FIBL 1; FIBL-1; FIBL1; OTTHUMP00000199864; OTTHUMP00000199865; OTTHUMP00000199866; OTTHUMP00000199867; OTTHUMP00000214005|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
fbln1 involved in several pathways and played different roles in them. We selected most pathways fbln1 participated on our site, such as Elastic fibre formation, Extracellular matrix organization, Molecules associated with elastic fibres, which may be useful for your reference. Also, other proteins which involved in the same pathway with fbln1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Elastic fibre formation||FBLN2; LOX; LOXL1; LTBP4; BMP10; ITGB3A; LOXL3; LOXL4; ABHD1; MFAP3|
|Extracellular matrix organization||ADAM8; ICAM4; JAM2B; FURINB; ADAMTS1; FAM49BA; LAMB1B; EFEMP1; LOXL3; LOXL2|
|Molecules associated with elastic fibres||EFEMP2; BMP10; MFAP1; LTBP4; MFAP5; MFAP2; MFAP4; FBLN1; MFAP3; LTBP3|
fbln1 has several biochemical functions, for example, calcium ion binding, extracellular matrix structural constituent, fibrinogen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by fbln1 itself. We selected most functions fbln1 had, and list some proteins which have the same functions with fbln1. You can find most of the proteins on our site.
|calcium ion binding||NOX5; MFGE8A; ITSN2B; PCDH17; S100Z; CALM; PCDH2G29; MMP14; PCDH2G10; GUCA1G|
|extracellular matrix structural constituent||TINAGL1; LAMC1; COL2A1A; COL27A1A; FBN1; OPTC; CHI3L1; EFEMP2; COL2A1B; FBN2B|
|fibrinogen binding||ITGA2B; FBLN1; THBS1; MFAP2|
|fibronectin binding||ITGB1A; PLEKHA2; FSTL3; CCDC80; MYOC; ITGA3; MMP13; ITGAV; CTSL1; ITGB3|
|identical protein binding||ACADM; RUNX1T1; PPPDE2; EWSR1; VPS41; AKT1; SIAH1; NQO1; TP53; EID3|
|integrin binding||DST; ADAM25; S1PR2; CD226; ICAM3; TSPAN4; LAMA5; COL3A1; EDIL3; ITGB5|
|peptidase activator activity||APP; FBLN1; MMP25; CLPX; FN1; CAV1; PSME4; MMP14; PSME4B; PINK1|
|protein C-terminus binding||XRCC5; HSPB7; SP1; AXIN1; COIL; MED12; HESX1; CTNNB1; IFT52; RAD51|
|protein binding||PIP4K2B; PRDM14; SCMH1; Ccl27a; KCTD5; PRUNE; INTS7; LCE4A; GP1BB; CD276|
|protein complex binding||TXN2; CTSL2; KLHL8; SHARPIN; GNB1; STRN4; PTPRF; CRIPT; MTHFR; Casp3|
fbln1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with fbln1 here. Most of them are supplied by our site. Hope this information will be useful for your research of fbln1.
APOA1; SMAD3; YWHAQ; MPG; Tubb4b; CACNA1A; BHLHE40; PLSCR1; FN1; TFAP2A; SKIL; TDGF1; ATN1; SMAD4; GFI1B; EDC4