Recombinant Human FBLN1 Protein, GST-tagged

• Cat.No.: FBLN1-3872H
• Product Overview: Human FBLN1 full-length ORF ( AAH22497.1, 1 a.a. - 683 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 100.8 kDa
• AA Sequence: MERAAPSRRVPLQLLLLGGLALLAA GVDADVLLEACCADGHRMATHQKDC SLPYATESKECRMVQEQCCHSQLEE LHCATGISLANEQDRCATPHGDNAS LEATFVKRCCHCCLLGRAAQAQGQS CEYSLMVGYQCGQVFRACCVKSQET GDLDVGGLQETDKIIEVEEEQEDPY LNDRCRGGGPCKQQCRDTGDEVVCS CFVGYQLLSDGVSCEDVNECITGSH SCRLGESCINTVGSFRCQRDSSCGT GYELTEDNSCKDIDECESGIHNCLP DFICQNTLGSFRCRPKLQCKSGFIQ DALGNCIDINECLSISAPCPIGHTC INTEGSYTCQKNVPNCGRGYHLNEE GTRCVDVDECAPPAEPCGKGHRCVN SPGSFRCECKTGYYFDGISRMCVDV NECQRYPGRLCGHKCENTLGSYLCS CSVGFRLSVDGRSCEDINECSSSPC SQECANVYGSYQCYCRRGYQLSDVD GVTCEDIDECALPTGGHICSYRCIN IPGSFQCSCPSSGYRLAPNGSNCQD IDECVTGIHNCSINETCFNIQGGFR CLAFECPENYRRSAATRCERLPCHE NRECSKLPLRITYYHLSFPTNIQAP AVVFRMGPSSAVPGDSMQLAITGGN EEGFFTTRKVSPHSGVVALTKPVPE PRDLLLTVKMDLSRHGTVSSFVAKL FIFVSAEL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FBLN1 fibulin 1 [ Homo sapiens ]
• Official Symbol: FBLN1
• Synonyms: FBLN1; fibulin 1; fibulin-1; FBLN; FIBL1
• Gene ID: 2192
• mRNA Refseq: NM_001996
• Protein Refseq: NP_001987
• MIM: 135820
• UniProt ID: P23142