Recombinant Human FBLN1 protein, MYC/DDK-tagged

• Cat.No.: FBLN1-16H
• Product Overview: Recombinant Human FBLN1, transcript variant D, fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 74.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: FBLN1 fibulin 1 [ Homo sapiens ]
• Official Symbol: FBLN1
• Synonyms: FBLN1; fibulin 1; fibulin-1; FBLN; FIBL1
• Gene ID: 2192
• mRNA Refseq: NM_006486
• Protein Refseq: NP_006477
• MIM: 135820
• UniProt ID: P23142
• Chromosome Location: 22q13.31
• Function: calcium ion binding; extracellular matrix structural constituent; peptidase activator activity