| Description : |
Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
77.24 kDa |
| AA Sequence : |
MERAAPSRRVPLPLLLLGGLALLAA GVDADVLLEACCADGHRMATHQKDC SLPYATESKECRMVQEQCCHSQLEE LHCATGISLANEQDRCATPHGDNAS LEATFVKRCCHCCLLGRAAQAQGQS CEYSLMVGYQCGQVFRACCVKSQET GDLDVGGLQETDKIIEVEEEQEDPY LNDRCRGGGPCKQQCRDTGDEVVCS CFVGYQLLSDGVSCEDVNECITGSH SCRLGESCINTVGSFRCQRDSSCGT GYELTEDNSCKDIDECESGIHNCLP DFICQNTLGSFRCRPKLQCKSGFIQ DALGNCIDINECLSISAPCPIGHTC INTEGSYTCQKNVPNCGRGYHLNEE GTRCVDVDECAPPAEPCGKGHRCVN SPGSFRCECKTGYYFDGISRMCVDV NECQRYPGRLCGHKCENTLGSYLCS CSVGFRLSVDGRSCEDINECSSSPC SQECANVYGSYQCYCRRGYQLSDVD GVTCEDIDECALPTGGHICSYRCIN IPGSFQCSCPSSGYRLAPNGRNCQD IDECVTGIHNCSINETCFNIQGGFR CLAFECPENYRRSAATLQQEKTDTV RCIKSCRPNDVTCVFDPVHTISHTV ISLPTFREFTRPEEIIFLRAITPPH PASQANIIFDITEGNLRDSFDIIKR YMDGMTVGVVRQVRPIVGPFHAVLK LEMNYVVGGVVSHRNVVNVHIFVSE YWFTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
