| Species : |
Human |
| Source : |
Wheat Germ |
| Tag : |
Non |
| Protein Length : |
683 amino acids |
| Description : |
Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3 end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants. |
| Molecular Weight : |
101.200kDa inclusive of tags |
| Tissue specificity : |
Isoform A and isoform B are only expressed in placenta. Isoform C and isoform D are expressed in a variety of tissues and cultured cells. |
| Form : |
Liquid |
| Purity : |
Proprietary Purification |
| Storage buffer : |
pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : |
MERAAPSRRVPLQLLLLGGLALLAAGVDADVLLEACCADG HRMATHQKDCSLPYATESKECRMVQEQCCHSQLEELHCAT GISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQ AQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQE TDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCS CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQ NTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCP IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC APPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDV NECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCE DINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE DIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNG SNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY RRSAATRCERLPCHENRECSKLPLRITYYHLSFPTNIQAP AVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSG VVALTKPVPEPRDLLLTVKMDLSRHGTVSSFVAKLFIFVS AEL |
| Sequence Similarities : |
Belongs to the fibulin family.Contains 3 anaphylatoxin-like domains.Contains 9 EGF-like domains. |
