Recombinant Human FBLN1 Protein (30-703 aa), His-Myc-tagged
Cat.No. : | FBLN1-2429H |
Product Overview : | Recombinant Human FBLN1 Protein (30-703 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the C-terminal and a Myc tag at the C-terminal. Research Area: Cancer. Protein Description: Full Length of Mature Protein. |
- Specification
- Gene Information
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Description : | Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP. |
Source : | Yeast |
Species : | Human |
Tag : | His-Myc |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 77.3 kDa |
Protein length : | 30-703 aa |
AA Sequence : | DVLLEACCADGHRMATHQKDCSLPY ATESKECRMVQEQCCHSQLEELHCA TGISLANEQDRCATPHGDNASLEAT FVKRCCHCCLLGRAAQAQGQSCEYS LMVGYQCGQVFQACCVKSQETGDLD VGGLQETDKIIEVEEEQEDPYLNDR CRGGGPCKQQCRDTGDEVVCSCFVG YQLLSDGVSCEDVNECITGSHSCRL GESCINTVGSFRCQRDSSCGTGYEL TEDNSCKDIDECESGIHNCLPDFIC QNTLGSFRCRPKLQCKSGFIQDALG NCIDINECLSISAPCPIGHTCINTE GSYTCQKNVPNCGRGYHLNEEGTRC VDVDECAPPAEPCGKGHRCVNSPGS FRCECKTGYYFDGISRMCVDVNECQ RYPGRLCGHKCENTLGSYLCSCSVG FRLSVDGRSCEDINECSSSPCSQEC ANVYGSYQCYCRRGYQLSDVDGVTC EDIDECALPTGGHICSYRCINIPGS FQCSCPSSGYRLAPNGRNCQDIDEC VTGIHNCSINETCFNIQGGFRCLAF ECPENYRRSAATLQQEKTDTVRCIK SCRPNDVTCVFDPVHTISHTVISLP TFREFTRPEEIIFLRAITPPHPASQ ANIIFDITEGNLRDSFDIIKRYMDG MTVGVVRQVRPIVGPFHAVLKLEMN YVVGGVVSHRNVVNVHIFVSEYWF |
Purity : | > 85% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA will be sent along with the products. Please refer to it for detailed information. |
Gene Name : | FBLN1 fibulin 1 [ Homo sapiens ] |
Official Symbol : | FBLN1 |
Synonyms : | FBLN1; fibulin 1; fibulin-1; FBLN; FIBL1; |
Gene ID : | 2192 |
mRNA Refseq : | NM_001996 |
Protein Refseq : | NP_001987 |
MIM : | 135820 |
UniProt ID : | P23142 |
Products Types
◆ Recombinant Protein | ||
FBLN1-1463H | Recombinant Human FBLN1 Protein, His-tagged | +Inquiry |
FBLN1-1464H | Recombinant Human FBLN1 Protein, His-tagged | +Inquiry |
Fbln1-724M | Recombinant Mouse Fbln1 Protein, His-tagged | +Inquiry |
FBLN1-01H | Active Recombinant Human FBLN1 Protein, HA-tagged | +Inquiry |
FBLN1-723H | Recombinant Human FBLN1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
FBLN1-598HCL | Recombinant Human FBLN1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionFBLN1 has been identified as a potential therapeutic target for the treatment of cardiovascular diseases due to its involvement in vascular function.
Genetic testing for FBLN1 mutations can be helpful in diagnosing certain connective tissue disorders.
The potential side effects of targeting FBLN1 as a therapeutic target are still under investigation and require further clinical trials.
FBLN1 has distinct roles and implications in clinical applications compared to other proteins, making it an important focus of research.
Mutations in the FBLN1 gene have been associated with developmental abnormalities in connective tissues, leading to connective tissue disorders such as Marfan syndrome and cutis laxa.
Customer Reviews (3)
Write a reviewThis partnership enhances research productivity while ensuring accurate and meaningful outcomes.
The manufacturer's commitment to maintaining stringent quality control measures guarantees that I can trust the protein's integrity and reliability throughout my experiments.
Its purity and stability ensure consistent and accurate results, making it an ideal tool for my research endeavors.
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