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Recombinant Human FBLN1 Protein (30-703 aa), His-Myc-tagged

Cat.No. : FBLN1-2429H
Product Overview : Recombinant Human FBLN1 Protein (30-703 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the C-terminal and a Myc tag at the C-terminal. Research Area: Cancer. Protein Description: Full Length of Mature Protein.
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Description : Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP.
Source : Yeast
Species : Human
Tag : His-Myc
Form : Tris-based buffer,50% glycerol
Molecular Mass : 77.3 kDa
Protein length : 30-703 aa
AA Sequence : DVLLEACCADGHRMATHQKDCSLPY ATESKECRMVQEQCCHSQLEELHCA TGISLANEQDRCATPHGDNASLEAT FVKRCCHCCLLGRAAQAQGQSCEYS LMVGYQCGQVFQACCVKSQETGDLD VGGLQETDKIIEVEEEQEDPYLNDR CRGGGPCKQQCRDTGDEVVCSCFVG YQLLSDGVSCEDVNECITGSHSCRL GESCINTVGSFRCQRDSSCGTGYEL TEDNSCKDIDECESGIHNCLPDFIC QNTLGSFRCRPKLQCKSGFIQDALG NCIDINECLSISAPCPIGHTCINTE GSYTCQKNVPNCGRGYHLNEEGTRC VDVDECAPPAEPCGKGHRCVNSPGS FRCECKTGYYFDGISRMCVDVNECQ RYPGRLCGHKCENTLGSYLCSCSVG FRLSVDGRSCEDINECSSSPCSQEC ANVYGSYQCYCRRGYQLSDVDGVTC EDIDECALPTGGHICSYRCINIPGS FQCSCPSSGYRLAPNGRNCQDIDEC VTGIHNCSINETCFNIQGGFRCLAF ECPENYRRSAATLQQEKTDTVRCIK SCRPNDVTCVFDPVHTISHTVISLP TFREFTRPEEIIFLRAITPPHPASQ ANIIFDITEGNLRDSFDIIKRYMDG MTVGVVRQVRPIVGPFHAVLKLEMN YVVGGVVSHRNVVNVHIFVSEYWF
Purity : > 85% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.
Gene Name : FBLN1 fibulin 1 [ Homo sapiens ]
Official Symbol : FBLN1
Synonyms : FBLN1; fibulin 1; fibulin-1; FBLN; FIBL1;
Gene ID : 2192
mRNA Refseq : NM_001996
Protein Refseq : NP_001987
MIM : 135820
UniProt ID : P23142

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any therapeutic implications of FBLN1 in cardiovascular diseases? 07/26/2022

FBLN1 has been identified as a potential therapeutic target for the treatment of cardiovascular diseases due to its involvement in vascular function.

Can FBLN1 be used for genetic testing in connective tissue disorders? 05/21/2021

Genetic testing for FBLN1 mutations can be helpful in diagnosing certain connective tissue disorders.

Are there any known side effects of targeting FBLN1 for therapeutic purposes? 05/07/2021

The potential side effects of targeting FBLN1 as a therapeutic target are still under investigation and require further clinical trials.

How does FBLN1 compare to other proteins in its clinical applications? 01/17/2018

FBLN1 has distinct roles and implications in clinical applications compared to other proteins, making it an important focus of research.

How is FBLN1 related to connective tissue disorders? 08/28/2017

Mutations in the FBLN1 gene have been associated with developmental abnormalities in connective tissues, leading to connective tissue disorders such as Marfan syndrome and cutis laxa.

Customer Reviews (3)

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Reviews
06/23/2017

    This partnership enhances research productivity while ensuring accurate and meaningful outcomes.

    07/27/2016

      The manufacturer's commitment to maintaining stringent quality control measures guarantees that I can trust the protein's integrity and reliability throughout my experiments.

      02/29/2016

        Its purity and stability ensure consistent and accurate results, making it an ideal tool for my research endeavors.

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