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FLII

  • Official Full Name

    flightless I homolog

  • Overview

    This gene encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. The gene is located within the Smith-Magenis syndrome region on chromosome 17.
  • Synonyms

    FLII; flightless I homolog (Drosophila); flightless I (Drosophila) homolog; protein flightless-1 homolog; FLI; Fli1; FLIL; MGC39265;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Bacillus subtilis
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E. coli or Yeast
  • E.coli
  • HEK293
  • Mammalian Cell
  • Yeast
  • His
  • His (Fc)
  • Avi
  • His|B2M
  • His|T7
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FLII-2953H Recombinant Human FLII Protein (Leu896-Phe1176), N-His tagged E.coli N-His Leu896-Phe1176
Human FLII-1738H Recombinant Human FLII protein, His & T7-tagged E.coli His/T7 Leu896~Phe1176 (Accession # Q13045)
Mouse FLII-5920M Recombinant Mouse FLII Protein Mammalian Cell His
Mouse FLII-1722M Recombinant Mouse FLII Protein (495-827 aa), His-tagged Yeast His 495-827 aa
Mouse FLII-2243M Recombinant Mouse FLII Protein (495-827 aa), His-B2M-tagged E.coli His/B2M 495-827 aa
Mouse FLII-3278M-B Recombinant Mouse FLII Protein Pre-coupled Magnetic Beads HEK293
Mouse FLII-3278M Recombinant Mouse FLII Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bacillus subtilis FLII-1163B Recombinant Bacillus subtilis FLII protein, His-tagged E. coli or Yeast His
Zebrafish FLII-8204Z Recombinant Zebrafish FLII Mammalian Cell His
Chicken FLII-2342C Recombinant Chicken FLII Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FLII Related Articles

FLII involved in several pathways and played different roles in them. We selected most pathways FLII participated on our site, such as XPodNet - protein-protein interactions in the podocyte expanded by STRING, which may be useful for your reference. Also, other proteins which involved in the same pathway with FLII were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
XPodNet - protein-protein interactions in the podocyte expanded by STRINGCHD1L;MTAP1A;CDC42EP5;SDK1;OASL2;GJB6;SNTB1;ARHGAP33;O3far1

FLII has several biochemical functions, for example, actin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FLII itself. We selected most functions FLII had, and list some proteins which have the same functions with FLII. You can find most of the proteins on our site.

Function Related Protein
actin bindingXIRP1;VPS16;AFAP1;MYOT;PIP;CLMN;PFN2L;CAPZA1A;EPB41L3B
protein bindingCLCNKB;EMP1;SNX5;RRP8;CDC40;DCLRE1B;DCUN1D4;SSX5;ANXA11

FLII has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FLII here. Most of them are supplied by our site. Hope this information will be useful for your research of FLII.

Camk2d; Camk2b; Ywhae; Ywhaz; Pgls

Ruzehaji, N; Kopecki, Z; et al. Attenuation of flightless I improves wound healing and enhances angiogenesis in a murine model of type 1 diabetes. DIABETOLOGIA 57:402-412(2014).
Kopecki, Z; Ruzehaji, N; et al. Topically Applied Flightless I Neutralizing Antibodies Improve Healing of Blistered Skin in a Murine Model of Epidermolysis Bullosa Acquisita. JOURNAL OF INVESTIGATIVE DERMATOLOGY 133:1008-1016(2013).
  • Q&As
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