FLRT3
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Official Full Name
fibronectin leucine rich transmembrane protein 3 -
Overview
This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. FLRTs may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. This gene is expressed in many tissues. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2010] -
Synonyms
FLRT3;fibronectin leucine rich transmembrane protein 3;HH21;leucine-rich repeat transmembrane protein FLRT3;fibronectin-like domain-containing leucine-rich transmembrane protein 3
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Zebrafish
- Mouse
- HEK293
- E.coli
- Mammalian Cells
- Human Cells
- Insect Cells
- His
- Non
- Avi
- Fc
- DDK
- Myc
Involved Pathway
FLRT3 involved in several pathways and played different roles in them. We selected most pathways FLRT3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FLRT3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FLRT3 has several biochemical functions, for example, chemorepellent activity,protein binding,protein binding, bridging. Some of the functions are cooperated with other proteins, some of the functions could acted by FLRT3 itself. We selected most functions FLRT3 had, and list some proteins which have the same functions with FLRT3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein homodimerization activity | GSTM4,ZFP652,NCR3,SNX6,DGAT2,SIAH1A,UGT1A1,MCL1A,ABP1,PRTFDC1 |
| protein binding, bridging | CNKSR1,SH2D1B,STUB1,CAV2,BCL3,SLC9A1,NEFL,VPS18,CUX1,CNTLN |
| protein binding | C1orf216,ERCC8,HIST2H3C,DNMT3L,DTX3L,TOR1AIP1,AES,ACP1,CSTF2T,C12orf5 |
| chemorepellent activity | EFNA5,SEMA3C,EPHA7,SEMA4E,SEMA4A,SEMA4D,SEMA4BA,SEMA3B,FLRT2,SEMA3AA |
| receptor signaling protein activity | TGFBR1,SMAD1,TRAIP,IL1RL1,BAG4,IFITM1,RGS14,FLRT2,PLCG1,KLK1B4 |
Interacting Protein
FLRT3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FLRT3 here. Most of them are supplied by our site. Hope this information will be useful for your research of FLRT3.
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References
- Dolan, J; Mitchell, KJ; et al. Mutation of Elfn1 in Mice Causes Seizures and Hyperactivity. PLOS ONE 8:-(2013).
- Lesch, KP; Merker, S; et al. Dances with black widow spiders: Dysregulation of glutamate signalling enters centre stage in ADHD. EUROPEAN NEUROPSYCHOPHARMACOLOGY 23:479-491(2013).
