FOXJ1
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Official Full Name
forkhead box J1 -
Overview
This gene encodes a member of the forkhead family of transcription factors. Similar genes in zebrafish and mouse have been shown to regulate the transcription of genes that control the production of motile cilia. The mouse ortholog also functions in the determination of left-right asymmetry. Polymorphisms in this gene are associated with systemic lupus erythematosus and allergic rhinitis. -
Synonyms
FOXJ1;forkhead box J1;FKHL13;forkhead box protein J1;HFH 4;HFH4;forkhead-like 13;fork head homologue 4;forkhead-related protein FKHL13;forkhead transcription factor HFH-4;hepatocyte nuclear factor 3 forkhead homolog 4;HFH-4;MGC35202
Recombinant Proteins
- Rat
- Human
- Mouse
- Mammalian Cells
- E.coli
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- Avi
- Fc
- GST
Involved Pathway
FOXJ1 involved in several pathways and played different roles in them. We selected most pathways FOXJ1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FOXJ1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FOXJ1 has several biochemical functions, for example, DNA binding,RNA polymerase II core promoter proximal region sequence-specific DNA binding,RNA polymerase II transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FOXJ1 itself. We selected most functions FOXJ1 had, and list some proteins which have the same functions with FOXJ1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | SALL1,ZNF74,NR3C1,ZNF567,ETV5,IRF4A,SMAD7,PAX6,BSX,SPI1B |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | DLX5,RBPJ,TFAP4,ESR1,TXK,NEUROD6,ATF4,IRF1,ELF1,WT1 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | RELA,PHOX2B,SMAD2,STAT3,SOX10,POU1F1,HOXA5,TBX15,MEF2A,RFX2 |
| DNA binding | TCEANC,PHF5A,HOXC11A,ZFP36L1,LZTS1,MEF2AA,HER9,AHRRB,STAT5B,ZNF285A |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | TFAP2A,NPAS4,ZNF446,FOXQ2,FOXI2,FLI1,FOXO1,ELF2A,GCM1,FOXB1A |
| transcription regulatory region sequence-specific DNA binding | NFKB1,NFE2L1,DDIT3,GATA1,ARNTL1A,SIN3A,SUV39H1,NONO,NFE2L2,BTBD8 |
Interacting Protein
FOXJ1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOXJ1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FOXJ1.
GRB2;OIP5;THRA;TWF2;SLC37A3;NMRAL1;TRMT6;RPUSD1
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References
- Hinderer, S; Schesny, M; et al. Engineering of fibrillar decorin matrices for a tissue-engineered trachea. BIOMATERIALS 33:5259-5266(2012).
- Van Haute, L; De Block, G; et al. Generation of lung epithelial-like tissue from human embryonic stem cells. RESPIRATORY RESEARCH 10:-(2009).
