Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

FRS3

  • Official Full Name

    Frs3 fibroblast growth factor receptor substrate 3

  • Synonyms

    FRS3; fibroblast growth factor receptor substrate 3; FRS2-beta; FGFR substrate 3; suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor); Snt2; AI449674; Frs2beta; 4930417B13Rik; MGC25496;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Sf9 Insect Cell
  • Wheat Germ
  • GST
  • GST|His
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FRS3-573H Recombinant Human FRS3 Protein, GST-His-tagged Sf9 Insect Cell GST/His
Human FRS3-1449H Recombinant Human FRS3, GST-tagged Sf9 Insect Cell GST
Human FRS3-29287TH Recombinant Human FRS3 N/A
Human FRS3-574H Recombinant Human FRS3 Protein, GST-His-tagged E.coli GST/His
Human FRS3-13009H Recombinant Human FRS3, GST-tagged E.coli GST N-term-303a.a.
Human FRS3-671HCL Recombinant Human FRS3 cell lysate N/A
Human FRS3-4508H Recombinant Human FRS3 Protein, GST-tagged Wheat Germ GST
Human FRS3-5070HF Recombinant Full Length Human FRS3 Protein, GST-tagged In Vitro Cell Free System GST 492 amino acids
Mouse FRS3-6049M Recombinant Mouse FRS3 Protein Mammalian Cell His
Mouse FRS3-3368M Recombinant Mouse FRS3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Frs3-1525M Recombinant Mouse Frs3 Protein, His-tagged E.coli N-His Ser3-Leu492
Mouse FRS3-3368M-B Recombinant Mouse FRS3 Protein Pre-coupled Magnetic Beads HEK293
Rat FRS3-2394R Recombinant Rat FRS3 Protein Mammalian Cell His
Rat FRS3-2050R Recombinant Rat FRS3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat FRS3-2050R-B Recombinant Rat FRS3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque FRS3-1753R Recombinant Rhesus monkey FRS3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque FRS3-1575R-B Recombinant Rhesus Macaque FRS3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque FRS3-1575R Recombinant Rhesus Macaque FRS3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FRS3 Related Articles

FRS3 involved in several pathways and played different roles in them. We selected most pathways FRS3 participated on our site, such as ARMS-mediated activation, Axon guidance, BDNF signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FRS3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ARMS-mediated activationSPNA2;DAB2IPB;FGF18B;JAK1;MARK3;HBEGF;CNKSR1;CRK;EGF
Axon guidanceTRPC3;EFNA1;WDR83;NRG2A;RHOAE;DUSP9;RND1;GPC1B;COL6A2
BDNF signaling pathwayCDKL5;JAK2;DPYSL2;EEF2;EGR2;CDK5;BCL2L11;EIF2S1;CSNK2A1
Cytokine Signaling in Immune systemCASPBL;IFIT14;DUSP4;FGF8B;ARIH1;DUSP10;DPF1;FGF18B;MX2
DAP12 interactionsSPNA2;DUSP5;SIGLEC15;DUSP6;MARK3;NRG2A;WDR83;DUSP2;SIGLEC14
DAP12 signalingFGF8B;SPTB;NEFLB;PHB;SPRED3;PAQR3B;NRG2A;CSF2RB;PRKAR1AA
Developmental BiologyLGI2A;DUSP2;EFNA2;MEF2AA;GDNF;CLTA;POU5F3;CACNG2;NR2F2
Downstream signal transductionPAQR3A;SPTBN2;FGFR1B;AGO3;RASGRP4;WDR83;SPTA1;SPTB;PEA15A

FRS3 has several biochemical functions, for example, fibroblast growth factor receptor binding, identical protein binding, insulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FRS3 itself. We selected most functions FRS3 had, and list some proteins which have the same functions with FRS3. You can find most of the proteins on our site.

Function Related Protein
fibroblast growth factor receptor bindingFGF2;FGF18B;FGF6;FGF10;Fgf15;FGF20;FGF5;FGF20A;FGF8A
identical protein bindingGOT1;NOD1;PAICS;ATXN10;SNX1;STAT6;ATG101;CD74;DYNLT1A
insulin receptor bindingSNX4;LMBRD1;PDPK1;INS2;PIK3R1;FRS2A;IGF1R;IGF2;DOK3
protein bindingNR2F2;ATXN10;ARMC8;LRRK1;MYBPC3;SLC2A1;THAP3;LILRB3;ASIC1

FRS3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FRS3 here. Most of them are supplied by our site. Hope this information will be useful for your research of FRS3.

PIK3R3; q9wmx2-pro_0000037548; PLSCR1; SPRY2; TCF4; GATA1; AES

Hryciw, T; MacDonald, JIS; et al. The fibroblast growth factor receptor substrate 3 adapter is a developmentally regulated microtubule-associated protein expressed in migrating and differentiated neurons. JOURNAL OF NEUROCHEMISTRY 112:924-939(2010).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
How does FRS3 participate in immune system regulation, and what clinical applications does this have? 12/15/2022

FRS3 is involved in immune response modulation, and understanding its function may lead to the development of immunotherapies or treatments for autoimmune disorders.

What clinical applications are associated with understanding FRS3's involvement in cancer? 07/21/2022

Targeting FRS3 may provide a novel approach for cancer therapy, and assessing its levels could serve as a diagnostic and prognostic marker.

How does FRS3 protein contribute to neurological disorders, and what clinical implications does this have 02/08/2019

FRS3 has been implicated in certain neurological disorders, and understanding its role may open avenues for therapeutic interventions in neurodegenerative diseases.

How is FRS3 protein implicated in cancer development? 07/28/2017

FRS3 has been found to be overexpressed in certain cancers, suggesting a potential role in promoting tumor growth and progression.

Are there any ongoing clinical trials investigating FRS3 as a therapeutic target for cancer treatment? 01/07/2017

Research is underway to explore the efficacy of FRS3-targeted therapies in clinical trials, evaluating its potential in cancer patients.

Customer Reviews (3)

Write a review
Reviews
01/13/2022

    The FRS3 protein not only fulfills my experimental requirements but is also backed by excellent technical support, which guarantees a smooth and successful research experience.

    07/15/2017

      The manufacturer of the FRS3 protein plays a vital role in supporting my trials.

      04/26/2017

        By using the FRS3 protein in my experiments, I am confident in obtaining accurate and dependable data.

        Ask a Question for All FRS3 Products

        Required fields are marked with *

        My Review for All FRS3 Products

        Required fields are marked with *

        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends