Recombinant Human FYN protein, His-tagged

• Cat.No.: FYN-0397H
• Product Overview: Recombinant Human FYN protein(231-483 aa), fused to His tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole.
• Protein length: 231-483 aa
• AA Sequence: YSGTWNGNTKVAIKTLKPGTMSPES FLEEAQIMKKLKHDKLVQLYAVVSE EPIYIVTEYMNKGSLLDFLKDGEGR ALKLPNLVDMAAQVAAGMAYIERMN YIHRDLRSANILVGNGLICKIADFG LARLIEDNEYTARQGAKFPIKWTAP EAALYGRFTIKSDVWSFGILLTELV TKGRVPYPGMNNREVLEQVERGYRM PCPQDCPISLHELMIHCWKKDPEER PTFEYLQSFLEDYFTATEPQYQPGE NL
• Purity: 95%, by SDS-PAGE with Coomassie Brilliant Blue staining.
• Storage: Short-term storage: Store at 2-8°C for (1-2 weeks).
  Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
• Reconstitution: Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
  Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage.

Gene Information

• Gene Name: FYN FYN oncogene related to SRC, FGR, YES [ Homo sapiens ]
• Official Symbol: FYN
• Synonyms: FYN; FYN oncogene related to SRC, FGR, YES; tyrosine-protein kinase Fyn; MGC45350; SLK; SYN; src-like kinase; proto-oncogene Syn; c-syn protooncogene; proto-oncogene c-Fyn; src/yes-related novel; tyrosine kinase p59fyn(T); OKT3-induced calcium influx regulator; p59-FYN
• Gene ID: 2534
• mRNA Refseq: NM_002037
• Protein Refseq: NP_002028
• MIM: 137025
• UniProt ID: P06241

Reviews

07/27/2020

the manufacturer fosters scientific collaboration and knowledge sharing among researchers.

02/27/2020

They can offer insights into interpreting results and assist in identifying trends or patterns that may be relevant to the specific research question.

12/23/2019

This guarantees a continuous and uninterrupted availability of the protein for researchers, eliminating concerns about potential shortages or delays.

Q&As

How does FYN protein affect synaptic plasticity?

FYN protein is involved in regulating synaptic plasticity, which plays a crucial role in learning and memory.

Is FYN protein involved in cancer biology?

Yes, FYN protein is also associated with cancer, particularly in regulating cell proliferation and survival.

Can targeting FYN protein have applications in autoimmune diseases?

Targeting FYN protein is being studied for its potential applications in the treatment of autoimmune diseases to modulate immune responses.

Are there any targeted therapies that inhibit FYN protein for cancer treatment?

Some targeted therapies aimed at inhibiting FYN protein have been explored for specific types of cancer.

Can FYN protein levels be measured in clinical settings?

Yes, FYN protein levels can be measured in clinical settings through various laboratory techniques.