Recombinant Human FYN protein, Flag-tagged, Biotinylated

• Cat.No.: FYN-50H
• Product Overview: Recombinant Human FYN[isoform a] [1-537(end) amino acids of accession number NP_002028.1] fused with DYKDDDDK tag at N-terminal was expressed in insect cell and biotinylated.

Specification

• Source: Insect cell
• Species: Human
• Tag: Flag
• Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
• Molecular Mass: 65 kDa
• Purity: >90% as determined by SDS-PAGE and CBB staining
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: FYN FYN oncogene related to SRC, FGR, YES [ Homo sapiens ]
• Official Symbol: FYN
• Synonyms: FYN; SLK; SYN; src-like kinase; proto-oncogene Syn; c-syn protooncogene; proto-oncogene c-Fyn; p59-FYN
• Gene ID: 2534
• mRNA Refseq: NM_002037
• Protein Refseq: NP_002028
• MIM: 137025
• UniProt ID: P06241
• Chromosome Location: 6q21
• Pathway: Adaptive Immune System, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Alpha-synuclein signaling, organism-specific biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; Antigen Activates B Cell Receptor Leading to Generation of Second Messengers, organism-specific biosystem
• Function: ATP binding; ephrin receptor binding; glycoprotein binding; metal ion binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; protein tyrosine kinase activity; protein tyrosine kinase activity

Reviews

07/27/2020

the manufacturer fosters scientific collaboration and knowledge sharing among researchers.

02/27/2020

They can offer insights into interpreting results and assist in identifying trends or patterns that may be relevant to the specific research question.

12/23/2019

This guarantees a continuous and uninterrupted availability of the protein for researchers, eliminating concerns about potential shortages or delays.

Q&As

How does FYN protein affect synaptic plasticity?

FYN protein is involved in regulating synaptic plasticity, which plays a crucial role in learning and memory.

Is FYN protein involved in cancer biology?

Yes, FYN protein is also associated with cancer, particularly in regulating cell proliferation and survival.

Can targeting FYN protein have applications in autoimmune diseases?

Targeting FYN protein is being studied for its potential applications in the treatment of autoimmune diseases to modulate immune responses.

Are there any targeted therapies that inhibit FYN protein for cancer treatment?

Some targeted therapies aimed at inhibiting FYN protein have been explored for specific types of cancer.

Can FYN protein levels be measured in clinical settings?

Yes, FYN protein levels can be measured in clinical settings through various laboratory techniques.