gabra6 Protein, gamma-aminobutyric acid (GABA) A receptor, alpha 6


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Official Full Name gamma-aminobutyric acid (GABA) A receptor, alpha 6
Background GABAA receptor subunit; part of a cerebellar receptor subtype, selective for antagonist of alcohol-induced motor incoordination and ataxia
Synonyms GABRA6; gamma-aminobutyric acid (GABA) A receptor, alpha 6; gamma-aminobutyric acid receptor subunit alpha-6; GABA A; GABA A Receptor alpha 6polypeptide; GABA A receptor alpha 6; GABA A receptor subunit alpha 6; GABA subunit A receptor alpha 6; GABA(A) receptor subunit alpha-6; GABRA 6; Gamma aminobutyric acid A receptor alpha 6; Gamma aminobutyric acid GABA A receptor alpha 6; Gamma aminobutyric acid receptor subunit alpha 6; GBRA6_HUMAN; MGC116903; MGC116904; GABA-A receptor alpha-6 subunit; gamma-aminobutyric acid A receptor, alpha 6; gamma-aminobutyric acidA receptor, alpha 6; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GABRA6-13096H Recombinant Human GABRA6, His-tagged E.coli His
    Human GABRA6-4643H Recombinant Human GABRA6 Protein, GST-tagged Wheat Germ GST
    Mouse GABRA6-6148M Recombinant Mouse GABRA6 Protein Mammalian Cell His
    Rat GABRA6-2447R Recombinant Rat GABRA6 Protein Mammalian Cell His
    Chicken GABRA6-6615C Recombinant Chicken GABRA6 Mammalian Cell His

    gabra6 involved in several pathways and played different roles in them. We selected most pathways gabra6 participated on our site, such as Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with gabra6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neuroactive ligand-receptor interaction APLNR; OPRD1; DRD4A; NPFFR2.1; GRM8B; ADRA2DA; TAAR12C; TAAR10A; CCKAR; GHRHRL
    Retrograde endocannabinoid signaling PLCB2; GABRG3; SLC17A8; GNGT2; PRKACA; GRIA1; GNAO1; MAPK1; NAPEPLD; PRKCG
    Morphine addiction PDE4C; GNG4; PDE11A; PRKACB; GABRA2; GNG12; GABRA3; Adcy4; PDE8B; GABRA1
    Nicotine addiction GABRG1; GABRB2; GABRA2; GABRG2; SLC17A6; GRIA4; GABRB3; GRIN2A; GRIN1; GRIN2B

    gabra6 has several biochemical functions, for example, contributes_to GABA-A receptor activity, benzodiazepine receptor activity, chloride channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by gabra6 itself. We selected most functions gabra6 had, and list some proteins which have the same functions with gabra6. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to GABA-A receptor activity GABRA2; GABRG3; GABRA6A; GABRA6; GABRZ; GABRR3A; GABRA4; GABRG1; GABRA3; GABRG2
    benzodiazepine receptor activity TSPO; GABRA6; GABRA3; GABRG2; GABRA2; GABRA4
    chloride channel activity SLC26A9; GABRP; CLCN1; GABRA1; SLC26A3.1; CFTR; CLCNKB; GABRA6A; GABRG2; FXYD3
    inhibitory extracellular ligand-gated ion channel activity GABRA1; GABRG1; GABRG3; GABRA5; GABRA4; GABRE; GABRA3; GABRB2; GABRA6; GABRA2

    gabra6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with gabra6 here. Most of them are supplied by our site. Hope this information will be useful for your research of gabra6.

    Ament, SA; Szelinger, S; et al. Rare variants in neuronal excitability genes influence risk for bipolar disorder. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:3576-3581(2015).
    Srivastava, S; Cohen, J; et al. A Novel Variant in GABRB2 Associated with Intellectual Disability and Epilepsy. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164A:2914-2921(2014).

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