GABRR1

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GABRR1

Official Full Name gamma-aminobutyric acid (GABA) receptor, rho 1
Background GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family.
Synonyms GABRR1; gamma-aminobutyric acid (GABA) receptor, rho 1; gamma-aminobutyric acid receptor subunit rho-1; bA135P14.1 (gamma-aminobutyric acid (GABA) receptor rho 1); GABA(A) receptor subunit rho-1; gamma aminobutyric acid receptor rho 1; gamma-aminobutyric acid (GABA) A receptor rho-1; gamma-aminobutyric acid (GABA) receptor rho 1; MGC163216; GABA(C) receptor; OTTHUMP00000016849; OTTHUMP00000209035; gamma-aminobutyric acid (GABA) A receptor, rho-1; bA135P14.1 (gamma-aminobutyric acid (GABA) receptor, rho 1)
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GABRR1-4651H Recombinant Human GABRR1 Protein Wheat Germ N/A
    Mouse GABRR1-6159M Recombinant Mouse GABRR1 Protein Mammalian Cell His
    Zebrafish GABRR1-3165Z Recombinant Zebrafish GABRR1 Mammalian Cell His

    GABRR1 involved in several pathways and played different roles in them. We selected most pathways GABRR1 participated on our site, such as Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GABRR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neuroactive ligand-receptor interaction GHRHRL; TAAR14E; P2RX4A; GRIK2; GABRD; GABRB2; ADRA2DB; AVPR2; GABRR2; HCRTR2
    Retrograde endocannabinoid signaling SLC17A8; GNG3; GABRG2; GRM1; SLC17A7; DAGLB; GRIA3; GABRB2; GNGT1; GNG2
    GABAergic synapse PRKCB; GNG13; NSF; GNG4; SLC38A3; GNG7; GABBR1; PRKCG; GNAI3; GNAO1
    Nicotine addiction GABRA1; GRIN2B; GABRR1; SLC17A6; GABRQ; GRIN3B; GRIN2A; GABRA4; GABRR2; GABRG2

    GABRR1 has several biochemical functions, for example, GABA receptor activity, GABA-A receptor activity, chloride channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GABRR1 itself. We selected most functions GABRR1 had, and list some proteins which have the same functions with GABRR1. You can find most of the proteins on our site.

    Function Related Protein
    GABA receptor activity GABRR1
    GABA-A receptor activity GABRR1; GABRG2; GABRA1; GABRR3; GABRR2A; GABRR2; GABRB3; GABRA6A; GABRE; GABRD
    chloride channel activity CLCA1; CLCN4; SLC26A2; FXYD3; GABRG1; CLCNKB; SLC26A7; SLC26A3.2; CLCN3; CLCA5
    extracellular ligand-gated ion channel activity CHRNA10A; CHRNB3A; GABRP; GLRBB; GABRD; CHRNA2A; GABRA6A; GABRZ; GABRR1; CHRNB3B
    protein domain specific binding CALM; ARL1; RUNX2; ARFIP1; HIST1H4K; TNNI3; ACTN2; PLAUR; VRK2; YWHABB
    protein heterodimerization activity ATF4; HIST1H4B; NFYBB; SOX9; BAXA; HIST3H2A; MTTP; CEBPB; DLG4B; OSTA
    protein homodimerization activity G6PDX; IZUMO1; CADM1B; PFKM; NR2C1; PLD6; MAP3K9; EPHX2; LGALS1; SRR

    GABRR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GABRR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GABRR1.

    Santoro, ML; Ota, VK; et al. Effect of antipsychotic drugs on gene expression in the prefrontal cortex and nucleus accumbens in the spontaneously hypertensive rat (SHR). SCHIZOPHRENIA RESEARCH 157:163-168(2014).
    Do, DN; Strathe, AB; et al. Genome-Wide Association Study Reveals Genetic Architecture of Eating Behavior in Pigs and Its Implications for Humans Obesity by Comparative Mapping. PLOS ONE 8:-(2013).

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