|Official Full Name||UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)|
|Background||This gene encodes a member of a family of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases, which catalyze the transfer of N-acetylgalactosamine (GalNAc) from UDP-GalNAc to a serine or threonine residue on a polypeptide acceptor in the initial step of O-linked protein glycosylation. Mutations in this gene are associated with an increased susceptibility to colorectal cancer.|
|Synonyms||GALNT12; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12); polypeptide N-acetylgalactosaminyltransferase 12; FLJ21212; CRCS1; GalNAc T12; GalNAc-T12; GalNAcT12; GALNT 12; GLT12_HUMAN; Polypeptide GalNAc transferase 12; Polypeptide N acetylgalactosaminyltransferase 12; pp GaNTase 12; pp-GaNTase 12; Protein UDP acetylgalactosaminyltransferase 12; Protein-UDP acetylgalactosaminyltransferase 12; UDP GalNAc polypeptide N acetylgalactosaminyltransferase 12; UDP GalNAc polypeptide N acetylgalactosaminyltransferase; UDP N acetyl alpha D galactosamine polypeptide N acetylgalactosaminyltransferase 12; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12; OTTHUMP00000021781; colorectal cancer, susceptibility to 1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
galnt12 involved in several pathways and played different roles in them. We selected most pathways galnt12 participated on our site, such as Mucin type O-Glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with galnt12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Mucin type O-Glycan biosynthesis||WBSCR17; GALNT4; GALNT7; ST6GALNAC1; GALNT18A; ST3GAL1; GALNT14; C1GALT1; GALNTL4; ST3GAL2|
|Metabolic pathways||ODC1; ATP6V1G2; SUCLA2; NDUFS3; CYP2P9; NDUFB2; OGDHL; PLD2; RDH12; ALDOAA|
galnt12 has several biochemical functions, for example, carbohydrate binding, metal ion binding, polypeptide N-acetylgalactosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by galnt12 itself. We selected most functions galnt12 had, and list some proteins which have the same functions with galnt12. You can find most of the proteins on our site.
|carbohydrate binding||LGALS2; OS9; CLEC11A; SIGLEC6; ZP3; KLRB1A; POC1BL; APCS; CLEC7A; LGALS3L|
|metal ion binding||HNRNPA0L; SDHD; ZSCAN1; ZBED3; OSR2; PLCH2; PCCA; NR1D2B; CD209; GALNT5|
|polypeptide N-acetylgalactosaminyltransferase activity||GALNT12; GALNT5; GALNT9; GALNT14; GALNT10; GALNT3; GALNTL4; GALNT6; GALNT7; C1GALT1C1|
galnt12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with galnt12 here. Most of them are supplied by our site. Hope this information will be useful for your research of galnt12.
BUB1; RB1; CDH1; SRC; BMPR1A; PIK3CA; MSH2; PMS2; CDKN2A; FBXW7; MLH3