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Official Full Name UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
Background This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. This gene is expressed specifically in the brain, with highest expression in the cerebellum. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms GALNT9; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9); polypeptide N-acetylgalactosaminyltransferase 9; GALNAC T9; Polypeptide GalNAc transferase 9; Polypeptide N acetylgalactosaminyltransferase 9; pp GaNTase 9; Protein UDP acetylgalactosaminyltransferase 9; UDP GalNAc polypeptide N acetylgalactosaminyltransferase 9; pp-GaNTase 9; GalNAc transferase 9; protein-UDP acetylgalactosaminyltransferase 9; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9; UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase 9; GALNAC-T9
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GALNT9-1254H Recombinant Human GALNT9 Protein, His-tagged E.coli His
    Human GALNT9-4708H Recombinant Human GALNT9 Protein, GST-tagged Wheat Germ GST
    Human GALNT9-6033HCL Recombinant Human GALNT9 293 Cell Lysate HEK293 N/A

    galnt9 involved in several pathways and played different roles in them. We selected most pathways galnt9 participated on our site, such as Mucin type O-Glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with galnt9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Mucin type O-Glycan biosynthesis GALNT4; C1GALT1C1; GCNT4A; GALNT18; GALNT14; GALNT6; GALNTL6; POC1BL; ST3GAL1; GCNT4
    Metabolic pathways POLR2J3; ADKB; NAT; C1GALT1B; NDUFV2; PLCD4; HADHAA; UGT1A6A; NDUFS4; RPIA

    galnt9 has several biochemical functions, for example, carbohydrate binding, metal ion binding, polypeptide N-acetylgalactosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by galnt9 itself. We selected most functions galnt9 had, and list some proteins which have the same functions with galnt9. You can find most of the proteins on our site.

    Function Related Protein
    carbohydrate binding KLRA8; CLC; SORD; WBSCR17; CD209C; REG3A; CLEC1B; CD55; GALNTL2; LGALS14
    metal ion binding ZBTB46; ITGA1; GLI2A; ZBTB33; ESR2A; NR1D1; ZNF530; NAIP7; NT5C2L1; DGKZ
    polypeptide N-acetylgalactosaminyltransferase activity GALNT6; GALNT7; GALNT3; C1GALT1C1; GALNT13; GALNT4; GALNTL4; GALNTL1; GALNTL2; GALNTL6

    galnt9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with galnt9 here. Most of them are supplied by our site. Hope this information will be useful for your research of galnt9.

    Tuupanen, S; Hanninen, UA; et al. Identification of 33 candidate oncogenes by screening for base-specific mutations. BRITISH JOURNAL OF CANCER 111:1657-1662(2014).
    Nakayama, Y; Nakamura, N; et al. Identification and expression analysis of zebrafish polypeptide alpha-N-acetylgalactosaminyltransferase Y-subfamily genes during embryonic development. GENE EXPRESSION PATTERNS 16:1-7(2014).

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