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GALR1

  • Official Full Name

    galanin receptor 1

  • Overview

    The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors.Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways.GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family.GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.
  • Synonyms

    GALR1; galanin receptor 1; GALNR, GALNR1; galanin receptor type 1; GAL1-R; GALR-1; OTTHUMP00000163778; GALNR; GALNR1;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Chicken
  • Homo sapiens (Human)
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Mouse GALR1-6197M Recombinant Mouse GALR1 Protein Mammalian Cell His
Mouse GALR1-3459M-B Recombinant Mouse GALR1 Protein Pre-coupled Magnetic Beads HEK293
Mouse GALR1-3459M Recombinant Mouse GALR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GALR1-2471R Recombinant Rat GALR1 Protein Mammalian Cell His
Rat GALR1-2127R-B Recombinant Rat GALR1 Protein Pre-coupled Magnetic Beads HEK293
Rat GALR1-2127R Recombinant Rat GALR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL29629HF Recombinant Full Length Human Galanin Receptor Type 1(Galr1) Protein, His-Tagged E.coli expression system His Full Length (1-349)
Mus musculus (Mouse) RFL14542MF Recombinant Full Length Mouse Galanin Receptor Type 1(Galr1) Protein, His-Tagged E.coli expression system His Full Length (1-348)
Rattus norvegicus (Rat) RFL2125RF Recombinant Full Length Rat Galanin Receptor Type 1(Galr1) Protein, His-Tagged E.coli expression system His Full Length (1-346)
Chicken GALR1-3844C Recombinant Chicken GALR1 Mammalian Cell His
Kit-1044 Phagocytosis Assay Kit (Red E. coli) N/A
Kit-0892 TR-FRET CAR Coactivator Assay Kit, rabbit N/A
Kit-1246 GALR1 CHO-K1 β-Arrestin GPCR Assay Kit N/A
Kit-1245 GALR1 Total GPCR Internalization Assay Kit N/A
Kit-1247 cAMP GALR1 CHO-K1 GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GALR1 Related Articles

GALR1 involved in several pathways and played different roles in them. We selected most pathways GALR1 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GALR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuroactive ligand-receptor interactionHRH1;TAAR7A;HTR4;CHRND;TAAR7F;NPY8BR;PRLRA;TAAR1B;ADORA2AA

GALR1 has several biochemical functions, for example, galanin receptor activity, neuropeptide binding, peptide hormone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GALR1 itself. We selected most functions GALR1 had, and list some proteins which have the same functions with GALR1. You can find most of the proteins on our site.

Function Related Protein
galanin receptor activityGAL;GALR2;GALR1;GALR3
neuropeptide bindingGPR1;OPRK1;SSTR5;OPRD1B;OPRD1A;SSTR4;NPY8BR;OPRL1;MRGPRB1
peptide hormone bindingAGTR2;GHRHR;NPR3;GALR1;ACVR1;AVPR1A;GHR;PTH1RB;NPR2
protein bindingHSPB2;FBXW8;CCNL2;IL18;FIG4;BCL6;CHCHD6;RPS15;RGS6

GALR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GALR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GALR1.

GAL

Guo, SC; Yan, FY; et al. Identification and validation of the methylation biomarkers of non-small cell lung cancer (NSCLC). Clinical Epigenetics 7:-(2015).
Metcalf, CS; Klein, BD; et al. Analgesic Properties of a Peripherally Acting and GalR2 Receptor-Preferring Galanin Analog in Inflammatory, Neuropathic, and Acute Pain Models. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 352:185-193(2015).
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