GEM

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GEM

Official Full Name GTP binding protein overexpressed in skeletal muscle
Background The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Synonyms GEM; GTP binding protein overexpressed in skeletal muscle; GTP-binding protein GEM; kinase inducible Ras like protein; KIR; GTP binding mitogen induced T cell protein; GTP binding protein expressed in mitogen stimulated T cells; GTP binding protein GEM; MGC26294; RAS like protein KIR; OTTHUMP00000226600; OTTHUMP00000226601; RAS-like protein KIR; kinase-inducible Ras-like protein; GTP-binding mitogen-induced T-cell protein; GTP-binding protein overexpressed in skeletal muscle
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GEM-13221H Recombinant Human GEM, GST-tagged E.coli GST
    Human GEM-5961HCL Recombinant Human GEM 293 Cell Lysate HEK293 N/A
    Human GEM-628H Recombinant Human GEM Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human GEM-6467H Recombinant Human GEM Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Gem-3187M Recombinant Mouse Gem Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse GEM-6299M Recombinant Mouse GEM Protein Mammalian Cell His
    Chicken GEM-7132C Recombinant Chicken GEM Mammalian Cell His
    Zebrafish GEM-4427Z Recombinant Zebrafish GEM Mammalian Cell His

    GEM involved in several pathways and played different roles in them. We selected most pathways GEM participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GEM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    GEM has several biochemical functions, for example, GDP binding, GTP binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GEM itself. We selected most functions GEM had, and list some proteins which have the same functions with GEM. You can find most of the proteins on our site.

    Function Related Protein
    GDP binding RHOB; SRP54A; RAB18; ARL3; MIEF1; RAB3B; RAB27B; RAB31; RAB10; RHOA
    GTP binding GNAT1; ARF5; RHEB; TUBA4L; TUBA1L; ARL17B; NOA1; DIRAS1A; TUBA3E; DNM1
    GTPase activity GNA11; RHOJ; GNAI2A; RAB8A; TUBA8L4; TUBA8L3; MFN1B; ADSSL1; EEF1A1A; RAB32A
    calmodulin binding PDE1A; MTAP6; MYLK; MYH1B; CAMKVB; SRY; SLC8A2; MIP; ITPKA; PHKG1B
    magnesium ion binding PI4K2A; ATP9B; PKMA; COMTB; CIB2; MARK2; PRPS1A; CDC42BPB; OPA1; STK36
    protein binding C7orf42; MICALL1; ISOC1; TAL1; UBA3; CSE1L; UQCRH; TMEM139; SLC16A3; SERPINA3

    GEM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GEM here. Most of them are supplied by our site. Hope this information will be useful for your research of GEM.

    TRIM23; CCDC102B; CCDC67; 147700; AHCYL1

    Hiroshima, Y; Maawy, AA; et al. Selective Efficacy of Zoledronic Acid on Metastasis in a Patient-Derived Orthotopic Xenograph (PDOX) Nude-Mouse Model of Human Pancreatic Cancer. JOURNAL OF SURGICAL ONCOLOGY 111:311-315(2015).
    Rowley, JS; Gray, SM; et al. Screening Potato Cultivars for new Sources of Resistance to Potato virus Y. AMERICAN JOURNAL OF POTATO RESEARCH 92:38-48(2015).

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