GJC1
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Official Full Name
gap junction protein, gamma 1, 45kDa
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Overview
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008] -
Synonyms
GJC1; gap junction protein, gamma 1, 45kDa; CX45; GJA7; gap junction gamma-1 protein; connexin 45; connexin-45; gap junction alpha-7 protein;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Canis lupus familiaris (Dog) (Canis familiaris)
- Chicken
- Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
- Danio rerio (Zebrafish) (Brachydanio rerio)
- Gallus gallus (Chicken)
- Homo sapiens (Human)
- Human
- Mesocricetus auratus (Golden hamster)
- Mus musculus (Mouse)
- Rattus norvegicus (Rat)
- Rhesus Macaque
- Sus scrofa (Pig)
- Xenopus laevis (African clawed frog)
- Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
- E.coli
- E.coli expression system
- HEK293
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | GJC1-13282H | Recombinant Human GJC1 protein, His-tagged | E.coli | His | 248-396 aa | |
| Human | GJC1-294HCL | Recombinant Human GJC1 lysate | HEK293 | N/A |
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| Human | GJC1-4923H | Recombinant Human GJC1 Protein, GST-tagged | Wheat Germ | GST |
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| Bos taurus (Bovine) | RFL20600BF | Recombinant Full Length Bovine Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-396) |
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| Canis lupus familiaris (Dog) (Canis familiaris) | RFL17598CF | Recombinant Full Length Dog Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-396) |
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| Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) | RFL18429CF | Recombinant Full Length Cricetulus Griseus Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-396) |
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| Danio rerio (Zebrafish) (Brachydanio rerio) | RFL35362DF | Recombinant Full Length Danio Rerio Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-380) |
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| Gallus gallus (Chicken) | RFL1022GF | Recombinant Full Length Chicken Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-394) |
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| Homo sapiens (Human) | RFL22112HF | Recombinant Full Length Human Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-396) |
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| Mesocricetus auratus (Golden hamster) | RFL35051MF | Recombinant Full Length Mesocricetus Auratus Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-396) |
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| Mus musculus (Mouse) | RFL27059MF | Recombinant Full Length Mouse Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-396) |
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| Rattus norvegicus (Rat) | RFL14177RF | Recombinant Full Length Rat Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-396) |
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| Rhesus Macaque | GJC1-1861R | Recombinant Rhesus monkey GJC1 Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | GJC1-1681R | Recombinant Rhesus Macaque GJC1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rhesus Macaque | GJC1-1681R-B | Recombinant Rhesus Macaque GJC1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Sus scrofa (Pig) | RFL32772SF | Recombinant Full Length Pig Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-396) |
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| Xenopus laevis (African clawed frog) | RFL10290XF | Recombinant Full Length Xenopus Laevis Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-377) |
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| Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | RFL11624XF | Recombinant Full Length Xenopus Tropicalis Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-377) |
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| Chicken | GJC1-7052C | Recombinant Chicken GJC1 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- GJC1 Related Articles
GJC1 involved in several pathways and played different roles in them. We selected most pathways GJC1 participated on our site, such as Calcium Regulation in the Cardiac Cell, Electric Transmission Across Gap Junctions, Gap junction assembly, which may be useful for your reference. Also, other proteins which involved in the same pathway with GJC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Calcium Regulation in the Cardiac Cell | RGS16;GJA8;RGS18;ADRB2;CHRM4;RGS4;CX34.4;GJC1;GJB2 |
| Electric Transmission Across Gap Junctions | GJC1;PANX1;PANX1B;PANX2;PANX1A;GJA10 |
| Gap junction assembly | GJB5;GJB3;CX27.5;GJC1;GJA8;GJB4;GJB2;GJA5;GJA4 |
| Gap junction trafficking | GJB5;GJB2;GJA8;MYO6;GJA4;GJC1;GJA5;GJB7;CX27.5 |
| Gap junction trafficking and regulation | GJB2;MYO6A;CX30.3;GJB7;GJB3;DAB2;GJA4;GJA5;GJB4 |
| Membrane Trafficking | TBC1D8B;BET1;CX27.5;HIP1R;TCEAL4;MYO6;SCFD1;SNX9A;CLVS2 |
| Neuronal System | CCDC167;KCNF1;LIN7B;LIN7C;KCNA1;KCNJ14;PPFIA4;CACNB4B;KCNH5 |
| Transmission across Electrical Synapses | GJC1;GJA10;PANX2;PANX1;PANX1A;PANX1B |
GJC1 has several biochemical functions, for example, gap junction channel activity, ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GJC1 itself. We selected most functions GJC1 had, and list some proteins which have the same functions with GJC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| gap junction channel activity | CX52.6;GJA1;CX43;GJB2;GJA8;CX23;PANX2;GJC1;GJC2 |
| ion channel activity | SCN8AB;TRPC6A;FXYD5;KCNC3B;CHRNB1L;SCN1LAB;TRPM4A;GRIA4B;CLCNK |
GJC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GJC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GJC1.
Sohl, G; Joussen, A; et al. Expression of connexin genes in the human retina. BMC OPHTHALMOLOGY 10:-(2010).
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