GJC3
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Official Full Name
gap junction protein, gamma 3, 30.2kDa -
Overview
This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells. Mutations in this gene have been reported to be associated with nonsyndromic hearing loss. -
Synonyms
GJC3;gap junction protein, gamma 3, 30.2kDa;gap junction protein, epsilon 1, 29kDa , GJE1;gap junction gamma-3 protein;connexin 30.2;CX30.2;connexin 29;connexin-30.2;connexin-31.3;gap junction epsilon-1 protein;CX29;GJE1;CX31.3
Recombinant Proteins
- Human
- Mouse
- Bovine
- Mammalian Cells
- HEK293
- E.coli
- His
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GJC3-1105H | Recombinant Human GJC3 | Mammalian Cells | Human | His |
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| GJC3-6381M | Recombinant Mouse GJC3 Protein | Mammalian Cells | Mouse | His |
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| GJC3-3035H | Recombinant Human GJC3 Protein, His (Fc)-Avi-tagged | HEK293 | Human | Avi&Fc&His |
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| GJC3-3035H-B | Recombinant Human GJC3 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| GJC3-3578M | Recombinant Mouse GJC3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| GJC3-3578M-B | Recombinant Mouse GJC3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| RFL15260MF | Recombinant Full Length Mouse Gap Junction Gamma-3 Protein(Gjc3) Protein, His-Tagged | E.coli | Mouse | His | Full L. Full Length (1-269) |
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| RFL3836BF | Recombinant Full Length Bovine Gap Junction Gamma-3 Protein(Gjc3) Protein, His-Tagged | E.coli | Bovine | His | Full L. Full Length (1-275) |
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| RFL7477HF | Recombinant Full Length Human Gap Junction Gamma-3 Protein(Gjc3) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-279) |
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Involved Pathway
GJC3 involved in several pathways and played different roles in them. We selected most pathways GJC3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GJC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
GJC3 has several biochemical functions, for example, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GJC3 itself. We selected most functions GJC3 had, and list some proteins which have the same functions with GJC3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein homodimerization activity | RAG1,APOA1BP,HSPB6,NR0B2,FAP,CADM1,AOC3,MAP3K13,CISD2,S100A16 |
Interacting Protein
GJC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GJC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GJC3.
Resources
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References
- Su, CC; Li, SY; et al. Mechanism of Two Novel Human GJC3 Missense Mutations in Causing Non-Syndromic Hearing Loss. CELL BIOCHEMISTRY AND BIOPHYSICS 66:277-286(2013).
- Kooshavar, D; Tabatabaiefar, MA; et al. Digenic inheritance in autosomal recessive non-syndromic hearing loss cases carrying GJB2 heterozygote mutations: Assessment of GJB4, GJA1, and GJC3. INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY 77:189-193(2013).
