GNAT1
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Official Full Name
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 -
Overview
Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified. -
Synonyms
GNAT1;guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1;guanine nucleotide-binding protein G(t) subunit alpha-1;GBT1;GNATR;guanine nucleotide binding protein (G protein) alpha transducing activity polypeptide 1;guanine nucleotide binding protein G(T) alpha 1 subunit;Rod specific transducin;OTTHUMP00000210665;OTTHUMP00000210666;transducin alpha-1 chain;transducin, rod-specific;rod-type transducin alpha subunit;guanine nucleotide-binding protein G(T), alpha-1 subunit;CSNBAD3
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GNAT1-6257C | Recombinant Chicken GNAT1 | Mammalian Cells | Chicken | His |
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| GNAT1-7021M | Recombinant Mouse GNAT1 Protein | Mammalian Cells | Mouse | His |
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| GNAT1-803H | Recombinant Human GNAT1 Protein, His-tagged | E.coli | Human | His |
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| GNAT1-9372Z | Recombinant Zebrafish GNAT1 | Mammalian Cells | Zebrafish | His |
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| GNAT1-3763M | Recombinant Mouse GNAT1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| GNAT1-3763M-B | Recombinant Mouse GNAT1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
GNAT1 involved in several pathways and played different roles in them. We selected most pathways GNAT1 participated on our site, such as Phototransduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNAT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Phototransduction | GUCY2E,CALML3,GNAT3,GRK1,PDE6A,GNAT2,RLN1,GUCA1A,GUCA1C,CALM3A |
Protein Function
GNAT1 has several biochemical functions, for example, G-protein beta/gamma-subunit complex binding,GTP binding,GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GNAT1 itself. We selected most functions GNAT1 had, and list some proteins which have the same functions with GNAT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PID1,C9orf78,S100A4,COQ9,ARHGAP33,ALG2,RB1,SPI1,RBM6,CAB39L |
| GTPase activity | RAB7,RAB17,TUBA3E,RRAS,RAC2,GNAT2,GNA12A,TUBB4B,GNGT1,RAB44 |
| G-protein beta/gamma-subunit complex binding | GNAZ,GNA13,GNA14,GNAI2B,GNAS,GNA15.1,CETN4,GNAI3,GNAO1A,GNAL |
| GTP binding | RAB7,GNL3,MX1,RAB4B,ARL15A,SRL,RHOT1B,IFT22,GIMAP3,RAB40A |
| guanyl nucleotide binding | GNA13A,GNA13B,GNA15.4,GNA11A,GNAO1B,GNAI2B,GNAIA,GNA11B,GNA15.1,GNA12A |
| metal ion binding | HPDA,MGRN1A,KLK1B3,TUT1,NEURL1AA,ZFYVE21,SALL3,ADPRHL2,ZNF311,TREX1 |
| nucleotide binding | HIPK3B,LOC81691,TRNAU1APB,SAFB,DAZL,RBM42,TDRD9,TTLL13,SNRNP70,MYHZ2 |
Interacting Protein
GNAT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNAT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNAT1.
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