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SERPINH1

  • Official Full Name

    serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)

  • Overview

    This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011]
  • Synonyms

    SERPINH1; serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); CBP1; CBP2; OI10; gp46; AsTP3; HSP47; PIG14; PPROM; RA-A47; SERPINH2; serpin H1; colligin-1; colligin-2; 47 kDa heat shock protein; arsenic-transactivated protein 3; rheumatoid arthritis antigen A-47; cell proliferation-inducing gene 14 protein; rheumatoid arthritis-related antigen RA-A47; serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2, (collagen-binding protein 2);

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • Mammalian Cell
  • Mammalian cells
  • Yeast
  • C
  • His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|SUMO
  • MYC
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SERPINH1-2602H Recombinant Human SERPINH1, GST-tagged E.coli GST 1-418aa
Human SERPINH1-822H Recombinant Human SERPINH1 Protein, His-tagged HEK293 His
Human SERPINH1-4718H Recombinant Human Serpin Peptidase Inhibitor, Clade H (heat shock protein 47), Member 1, (collagen binding protein 1), His-tagged Human His
Human SERPINH1-28425TH Recombinant Human SERPINH1, His-tagged E.coli His
Human SERPINH1-1936HCL Recombinant Human SERPINH1 293 Cell Lysate HEK293 N/A
Human SERPINH1-329H Recombinant Human SERPINH1 protein, His-tagged HEK293 His 400
Human SERPINH1-2687H Recombinant Human SERPINH1 Protein, His-tagged E.coli N-His Pro30-Leu418
Human SERPINH1-1983H Recombinant Human SERPINH1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human SERPINH1-495HFL Recombinant Full Length Human SERPINH1 Protein, C-Flag-tagged Mammalian cells Flag
Human SERPINH1-068H Recombinant Human SERPINH1 Protein, N-His-tagged E.coli N-His 418
Human SERPINH1-576H Recombinant Human SERPINH1 Protein, His-tagged HEK293 His 418
Human SERPINH1-1983H-B Recombinant Human SERPINH1 Protein Pre-coupled Magnetic Beads HEK293
Human SERPINH1-6656H Recombinant Human SERPINH1 Protein (Ala19-Leu418), C-His tagged Mammalian cells C-His Ala19-Leu418
Mouse SERPINH1-14964M Recombinant Mouse SERPINH1 Protein Mammalian Cell His
Mouse SERPINH1-1516M Recombinant Mouse SERPINH1 Protein (18-417 aa), His-tagged Yeast His 18-417 aa
Mouse SERPINH1-8059M Recombinant Mouse SERPINH1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SERPINH1-808M Recombinant Mouse SERPINH1 Protein (18-417 aa), His-SUMO-tagged E.coli His/SUMO 18-417 aa
Mouse SERPINH1-8059M-B Recombinant Mouse SERPINH1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Serpinh1-5517M Recombinant Mouse Serpinh1 protein, His-tagged Yeast His 18-417aa
Mouse Serpinh1-790M Recombinant Mouse Serpinh1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat SERPINH1-5346R Recombinant Rat SERPINH1 Protein Mammalian Cell His
Rat SERPINH1-5005R Recombinant Rat SERPINH1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SERPINH1-5005R-B Recombinant Rat SERPINH1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SERPINH1-4155R Recombinant Rhesus monkey SERPINH1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SERPINH1-3972R Recombinant Rhesus Macaque SERPINH1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SERPINH1-3972R-B Recombinant Rhesus Macaque SERPINH1 Protein Pre-coupled Magnetic Beads HEK293
Chicken SERPINH1-6843C Recombinant Chicken SERPINH1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SERPINH1 Related Articles

SERPINH1 involved in several pathways and played different roles in them. We selected most pathways SERPINH1 participated on our site, such as Collagen biosynthesis and modifying enzymes, Collagen formation, Endochondral Ossification, which may be useful for your reference. Also, other proteins which involved in the same pathway with SERPINH1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Collagen biosynthesis and modifying enzymesPCOLCEA;SERPINH1B;PCOLCEB;COL4A5;COL8A1A;COL23A1;LEPREL2;LEPRE1;TLL1
Collagen formationCOL2A1;CTSL1;COL4A4;MMP20;PCOLCE2B;CTSB;EMID2;COL1A1;COL10A1
Endochondral OssificationFRZB;CST5;SOX6;ADAMTS5;MGP;ADAMTS4;SOX9A;RUNX2A;MMP13
Extracellular matrix organizationCOL6A2;MGC174155;BMP1A;TIMP2;MMP10;COL28A1;CRTAP;MUSK;COL1A1

SERPINH1 has several biochemical functions, for example, collagen binding, poly(A) RNA binding, serine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SERPINH1 itself. We selected most functions SERPINH1 had, and list some proteins which have the same functions with SERPINH1. You can find most of the proteins on our site.

Function Related Protein
collagen bindingPDGFB;HSD17B12;CTSK;FN1;LUM;VWF;PCOLCE2;ITGA1;CTSB
poly(A) RNA bindingGLTSCR2;YBX1;G3BP1;LUC7L2;PRRC2A;SRP72;HNRNPU;GOT2;RBM12B2
serine-type endopeptidase inhibitor activityHRG;SERPINB1L4;WFIKKN2;SERPINI2;SPINK13;SERPINF1;SERPINB6;SPINLW1;SPINT1
unfolded protein bindingTCP1;TRAP1;HSPA5;TTC1;HSP26;HSPA6;HSP90AA1.1;HSPA2;CCDC102A

SERPINH1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SERPINH1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SERPINH1.

TSC22D1; CRELD2; nrdR; SLC35F6; CEP70; FEZ1; NSG2; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; 15-deoxy-delta(12,14; MYC; ESR1; env; ATF2; GABARAPL2; GRB2; YBX1; IQCB1; AARSD1

Saeed, H; Iqtedar, M; et al. Aberrant gene expression profiles, during in vitro osteoblast differentiation, of telomerase deficient mouse bone marrow stromal stem cells (mBMSCs). JOURNAL OF BIOMEDICAL SCIENCE 22:-(2015).
Yoo, Y; Byun, K; et al. Amyloid-Beta-Activated Human Microglial Cells Through ER-Resident Proteins. JOURNAL OF PROTEOME RESEARCH 14:214-223(2015).
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