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Official Full Name G protein-coupled receptor 119
Synonyms GPR119; G protein-coupled receptor 119; glucose-dependent insulinotropic receptor; GPCR2; hGPCR2; G-protein coupled receptor 2; G-protein coupled receptor 119; MGC119957
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GPR119-5176H Recombinant Human GPR119 Protein Wheat Germ N/A
    Human GPR119-5177H Recombinant Human GPR119 Protein, GST-tagged Wheat Germ GST
    Human GPR119-5800HCL Recombinant Human GPR119 293 Cell Lysate HEK293 N/A
    Mouse GPR119-7132M Recombinant Mouse GPR119 Protein Mammalian Cell His
    Rat GPR119-2648R Recombinant Rat GPR119 Protein Mammalian Cell His

    gpr119 involved in several pathways and played different roles in them. We selected most pathways gpr119 participated on our site, such as Incretin synthesis, secretion, and inactivation, Insulin secretion, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with gpr119 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Incretin synthesis, secretion, and inactivation SPCS3; GPR119; DPP4; GPR120; PCSK1; GRP; CDX2; O3far1; SLC38A8
    Insulin secretion CCKAR; PRKCB; SNAP25; KCNMB2; ATP1B1; INS; RAPGEF4; PRKACG; GNAS; PDX1
    Metabolism of proteins TIMM21; SERPINA7; MTX1; CALCA; YY2; PFDN4; PHC3; RHBDL1; SEC23IP; SCFD1
    Peptide hormone metabolism EXOC8; DPP4; PCSK1; CGB5; MBOAT4; PCSK2; CMA1; SLC30A6; INHA; CPA3
    Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) PCSK1; SPCS3; DPP4; SLC38A8; GPR119; O3far1; CDX2
    Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) GPR119; PCSK1; DPP4
    cAMP signaling pathway GRIA4; MAPK8; PLCE1; GNAS; PPP1CC; MAPK9; CALM1; CNGA4; PRKACB; VAV3

    gpr119 has several biochemical functions, for example, G-protein coupled receptor activity, phosphatidylcholine binding. Some of the functions are cooperated with other proteins, some of the functions could acted by gpr119 itself. We selected most functions gpr119 had, and list some proteins which have the same functions with gpr119. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity GPR128; TAAR15; GRM3; OR51E2; OLFR492; VMN1R44; GPR4; MRGPRB5; OR10J1; OR13A1
    phosphatidylcholine binding PCTP; APOA2; CHMP3; GPR12; VPS24; APOA4A; ESYT2; NF1; RPE65; APOA4B.2

    gpr119 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with gpr119 here. Most of them are supplied by our site. Hope this information will be useful for your research of gpr119.

    Cornall, LM; Hryciw, DH; et al. Direct activation of the proposed anti-diabetic receptor, GPR119 in cardiomyoblasts decreases markers of muscle metabolic activity. MOLECULAR AND CELLULAR ENDOCRINOLOGY 402:72-85(2015).
    Engelstoft, MS; Norn, C; et al. Structural basis for constitutive activity and agonist-induced activation of the enteroendocrine fat sensor GPR119. BRITISH JOURNAL OF PHARMACOLOGY 171:5774-5789(2014).

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