GPR68

  • Official Full Name

    G protein-coupled receptor 68

  • Overview

    Ovarian cancer G-protein coupled receptor 1 is a protein that in humans is encoded by the GPR68 gene.

  • Synonyms

    GPR68;G protein-coupled receptor 68;ovarian cancer G-protein coupled receptor 1;OGR1;G-protein coupled receptor 68;sphingosylphosphorylcholine receptor;ovarian cancer G protein-coupled receptor, 1;GPR12A;MGC111379;MGC156983

    Involved Pathway

    GPR68 involved in several pathways and played different roles in them. We selected most pathways GPR68 participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (q) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR68 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    GPCR downstream signaling UTS2D,NMU,RGS7,GPR132B,LPAR2A,PENK,MLN,ARHGEF3,PRKCHB,NPB
    GPCRs, Class A Rhodopsin-like CCR1,OR10A5,PTGDR2,CNR2,OPN1MW2,CX3CR1,OPN1MW,GPR4,CMKLR1,GPR75
    Class A/1 (Rhodopsin-like receptors) CNR1,DRD2,OXER1,PROKR1,CCR1,LTB4R,GPR65,CCK,CCR5,CYSLTR1
    G alpha (q) signalling events HCRT,TRH,NMBB,EDN2,EDN1,CCK,APPA,GPR4,PRKCHB,TAE1
    Osteoclast Signaling AIMP2
    GPCR ligand binding TAS2R7,AMCF-II,CALCA,CCR7,NMUR1,EDNRA,TAC1,GPR31B,ANXA1,CCL35.2
    Gastrin-CREB signalling pathway via PKC and MAPK RGS18,NMU,ANXA1,EDN2,UTS2D,OPN4.1,TAE1,ANXA1C,DGKG,LPAR5A
    Signal Transduction NEDD8L,RHOUA,PRKCHB,NOXO1A,SRY,ARAP1,DEPDC7,PENK,TAGAPB,RARGA

    Protein Function

    GPR68 has several biochemical functions, for example, G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR68 itself. We selected most functions GPR68 had, and list some proteins which have the same functions with GPR68. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity TAAR12I,CCR10,TAAR19P,SMO,TAAR10B,OR2B3,OPNP,PTGER4B,OR5H1,OLFR488

    Interacting Protein

    GPR68 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR68 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR68.

    Resources

    Research Area

    References

    • Yang, MH; Mailhot, G; et al. Expression of and role for ovarian cancer G-protein-coupled receptor 1 (OGR1) during osteoclastogenesis. JOURNAL OF BIOLOGICAL CHEMISTRY 281:23598-23605(2006).

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All GPR68 Products

    Required fields are marked with *

    My Review for All GPR68 Products

    Required fields are marked with *