grhl1 Protein, grainyhead-like 1 (Drosophila)


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Official Full Name grainyhead-like 1 (Drosophila)
Background This gene encodes a member of the grainyhead family of transcription factors. The encoded protein can exist as a homodimer or can form heterodimers with sister-of-mammalian grainyhead or brother-of-mammalian grainyhead. This protein functions as a transcription factor during development. [provided by RefSeq, Jun 2009]
Synonyms GRHL1; grainyhead-like 1 (Drosophila); MGR; NH32; LBP32; TFCP2L2; grainyhead-like protein 1 homolog; LBP protein 32; mammalian grainyhead; transcription factor LBP-32; transcription factor CP2-like 2;
    • Species :
    • Human
    • Mouse
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GRHL1-5325H Recombinant Human GRHL1 Protein, GST-tagged Wheat Germ GST
    Human GRHL1-5751HCL Recombinant Human GRHL1 293 Cell Lysate HEK293 N/A
    Mouse GRHL1-7253M Recombinant Mouse GRHL1 Protein Mammalian Cell His

    grhl1 involved in several pathways and played different roles in them. We selected most pathways grhl1 participated on our site, such as Fatty acid, triacylglycerol, and ketone body metabolism, Metabolism, Metabolism of lipids and lipoproteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with grhl1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Fatty acid, triacylglycerol, and ketone body metabolism ECI1; HELZ2; ACOT11; Agmo; MED20; CDK8; THEM5; MTF1; ACOT12; ACOT6
    Metabolism SLC25A32; CYP51A1; CYP2U1; DPEP2; DCK; CYP2R1; KIAA1199; NUDT3B; GSTK1; DBH
    Metabolism of lipids and lipoproteins ABHD3; MTP; CHKA; CYP2AD3; GLIPR1; CERS3B; ARV1; PNPLA8; CYP2V1; AGPAT6
    PPARA activates gene expression MED18; MED22; G0S2; MED19; CTGF; GRHL1; TIAM2; CDK19; MED25; MTF1
    Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) MED15; MED6; MED21; MED20; MED9; MED18; G0S2; ANKRD1; MED26; MED25

    grhl1 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, chromatin DNA binding, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by grhl1 itself. We selected most functions grhl1 had, and list some proteins which have the same functions with grhl1. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II core promoter proximal region sequence-specific DNA binding SREBF1; CREB1; KLF16; FEZF2; PITX1; NFATC2; ETV4; CC2D1A; PBX1; ISL1
    chromatin DNA binding FOXC2; PRDM14; GRHL2; HIST1H1E; VAX1; THRB; HIST1H1C; GRHL3; PPARGC1A; VAX2
    sequence-specific DNA binding HOXB9; IRX6; SOX2; SOX30; IRX4A; PPARAA; FOXK2; FOXQ1B; SOX7; DBX1A
    transcription regulatory region DNA binding TRP53; MTERFD1; TRP63; ZFP513; BCL11AB; BRD7; MEN1; SALL1; GATA4; TBL1X
    transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding CEBPE; ELF4; NR4A3; NR3C1; SIX4; EBF2; NFYC; NDN; BCL11B; KCNA3

    grhl1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with grhl1 here. Most of them are supplied by our site. Hope this information will be useful for your research of grhl1.


    Kohn, KW; Zeeberg, BM; et al. Gene Expression Correlations in Human Cancer Cell Lines Define Molecular Interaction Networks for Epithelial Phenotype. PLOS ONE 9:-(2014).
    Fabian, J; Lodrini, M; et al. GRHL1 Acts as Tumor Suppressor in Neuroblastoma and Is Negatively Regulated by MYCN and HDAC3. CANCER RESEARCH 74:2604-2616(2014).

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