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GTF2A1L

Official Full Name

general transcription factor IIA, 1-like
Overview

The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Synonyms

GTF2A1L; general transcription factor IIA, 1-like; TFIIA-alpha and beta-like factor; ALF; TFIIA alpha/beta like factor; Stonin 1; General transcription factor II A 1 like factor; GTF2A1LF; SALF; TFIIA alpha and beta like factor; GTF2A1-like factor; OTTHUMP00000201062; OTTHUMP00000201165; TFIIA-alpha/beta-like factor; TFIIA large subunit isoform ALF; general transcription factor II A, 1-like factor; Limulus Antilipopolysaccharide Factor; LALF;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
P.pastoris
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GTF2A1L-458H	Recombinant Human GTF2A1L Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GTF2A1L-418H	Recombinant Human GTF2A1L Protein, His-tagged	E.coli	His		Inquiry
Human	GTF2A1L-5705HCL	Recombinant Human GTF2A1L 293 Cell Lysate	HEK293	N/A		Inquiry
Human	GTF2A1L-1425HF	Recombinant Full Length Human GTF2A1L Protein, GST-tagged	In Vitro Cell Free System	GST	478 amino acids	Inquiry
Mouse	GTF2A1L-7351M	Recombinant Mouse GTF2A1L Protein	Mammalian Cell	His		Inquiry
Mouse	GTF2A1L-3987M	Recombinant Mouse GTF2A1L Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	GTF2A1L-3987M-B	Recombinant Mouse GTF2A1L Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	GTF2A1L-4478Z	Recombinant Zebrafish GTF2A1L	Mammalian Cell	His		Inquiry
Chicken	GTF2A1L-4504C	Recombinant Chicken GTF2A1L	Mammalian Cell	His		Inquiry
	ALF-240L	Recombinant Limulus Antilipopolysaccharide Factor	P.pastoris	N/A		Inquiry

Involved Pathway
Protein Function
Interacting Protein

GTF2A1L involved in several pathways and played different roles in them. We selected most pathways GTF2A1L participated on our site, such as Basal transcription factors, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2A1L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Basal transcription factors	GTF2F2;TAF15;TAF9B;GTF2H2C_2;MNAT1;TAF8;TAF1;ERCC2;GTF2IRD1
Viral carcinogenesis	MRPS18B;PIK3CA;GTF2A2;VAC14;SCRIB;GTF2A1;HDAC7;SNW1;HIST1H2BM

GTF2A1L has several biochemical functions, for example, DNA binding, protein binding, transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2A1L itself. We selected most functions GTF2A1L had, and list some proteins which have the same functions with GTF2A1L. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	TXLNB;HMGB2;TOPORS;PAX1;KLF7;CENPC1;HOMEZB;EXO5;ZIM3
protein binding	KLF11;FAM123A;MAGEF1;LTA4H;SERPINB3C;STK38;CRB1;PYDC1;EIF5A
transcription coactivator activity	ARL2BP;KMT2E;NR1I3;ABT1;MKL1B;SCAND1;TUBB3;TFAP2A;YAP1

GTF2A1L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2A1L here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2A1L.