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GTF3C3

Official Full Name

general transcription factor IIIC, polypeptide 3, 102kDa
Overview

The protein encoded by this gene is part of the TFIIIC2 complex, which binds to the promoters of small nuclear and cytoplasmic RNA genes in order to recruit RNA polymerase III. The TFIIIC2 complex is composed of six subunits. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms

GTF3C3; general transcription factor IIIC, polypeptide 3, 102kDa; general transcription factor IIIC, polypeptide 3 (102kD); general transcription factor 3C polypeptide 3; TFiiiC2 102; TFIIIC102; general transcription factor IIIC, polypeptide 3, 102kD; TFIIIC gamma; TFIIICgamma; transcription factor IIIC 102 kDa subunit; transcription factor IIIC gamma subunit; Transcription factor IIIC subunit gamma; transcription factor IIIC, 102 kD; TF3C-gamma; OTTHUMP00000163622; OTTHUMP00000205595; TFIIIC 102 kDa subunit; TFiiiC2-102;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Rhesus Macaque
Zebrafish

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GTF3C3-4463H	Recombinant Human GTF3C3 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GTF3C3-765HCL	Recombinant Human GTF3C3 cell lysate		N/A		Inquiry
Human	GTF3C3-3416HF	Recombinant Full Length Human GTF3C3 Protein, GST-tagged	In Vitro Cell Free System	GST	886 amino acids	Inquiry
Rhesus Macaque	GTF3C3-2012R	Recombinant Rhesus monkey GTF3C3 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	GTF3C3-1833R	Recombinant Rhesus Macaque GTF3C3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	GTF3C3-1833R-B	Recombinant Rhesus Macaque GTF3C3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	GTF3C3-8137Z	Recombinant Zebrafish GTF3C3	Mammalian Cell	His		Inquiry
Chicken	GTF3C3-1653C	Recombinant Chicken GTF3C3	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

GTF3C3 involved in several pathways and played different roles in them. We selected most pathways GTF3C3 participated on our site, such as Gene Expression, RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription, RNA Polymerase III Abortive And Retractive Initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF3C3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Gene Expression	NT5C3B;MBD3A;JARID2B;MTA1;PHF1;BCAS2;Txn1;ZNF331;ZNF45
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription	SNAPC1;GTF3C2;SNAPC5;ZNF143;GTF3AB;ZFP143;MTERF;PTRF;POLRMT
RNA Polymerase III Abortive And Retractive Initiation	NFIX;GTF3C4;BRF2;NFIB;NFIC;SNAPC4;BRF1;SNAPC5;GTF3C2
RNA Polymerase III Transcription	GTF3AB;NFIX;SNAPC2;GTF3C4;ZFP143;ZNF143;GTF3C2;SNAPC5;POU2F1B
RNA Polymerase III Transcription Initiation	POU2F1B;ZNF143;BRF1;ZFP143;GTF3C4;GTF3AB;SNAPC1;SNAPC2;GTF3AA
RNA Polymerase III Transcription Initiation From Type 1 Promoter	GTF3C3;BRF1;GTF3C4;GTF3AB;GTF3C2;GTF3A;GTF3C5;GTF3AA;POLR3GLA
RNA Polymerase III Transcription Initiation From Type 2 Promoter	GTF3C5;BRF1B;GTF3C3;GTF3C2;GTF3C4;BRF1

GTF3C3 has several biochemical functions, for example, contributes_to DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF3C3 itself. We selected most functions GTF3C3 had, and list some proteins which have the same functions with GTF3C3. You can find most of the proteins on our site.

Function	Related Protein
contributes_to DNA binding	MCM7;SMAD4;MRE11A;GTF3C4;NFE2L2A;GTF3C2;GTF3C3;AHR2;SMAD2
protein binding	SMN2;FAM76B;FANCG;FKBP1A;MLLT1;STX16;ANKRD17;NEBL;ZNF785

GTF3C3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF3C3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF3C3.

MYC; CIAO1; MAGEA6; SQSTM1; Gtf3c6; GSTK1; HTT; q5ngt9_fratt; cirA2; Ubr5; Smad6; PLK1; GABARAPL2; Actb; PCDH1; SNW1; P