H2-AB1
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Official Full Name
histocompatibility 2, class II antigen A, beta 1 -
Synonyms
H2-AB1;histocompatibility 2, class II antigen A, beta 1;Abeta;AI845868;H2 Ab;H2 Ab1;H2 I A beta;Histocompatibility 2 class II antigen A beta 1;Ia2;Iab;MHC class II antigen I A beta 1;Rmcs1;OTTMUSP00000053328;MHC class II H2-IA-beta-psi;MHC class II antigen A beta;response to metastatic cancers 1;major histocompatibility complex class II beta chain;H-2 class II histocompatibility antigen, A be;Ia-2;H-2Ab;H2-Ab;I-Abeta
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| H2-AB1-7425M | Recombinant Mouse H2-AB1 Protein | Mammalian Cells | Mouse | His |
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| H2-AB1-4039M | Recombinant Mouse H2-AB1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| H2-AB1-4039M-B | Recombinant Mouse H2-AB1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
H2-AB1 involved in several pathways and played different roles in them. We selected most pathways H2-AB1 participated on our site, such as Phagosome,Cell adhesion molecules (CAMs),Antigen processing and presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with H2-AB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Toxoplasmosis | MAPK8,NFKB1,HLA-DPB1,HLA-DOB,GNAI3,TGFB3,STAT1,HLA-DMA,PIK3CB,LAMA5 |
| ne thyroid disease | HLA-B,HLA-DPA1,HLA-DQA2,HLA-DRB3,Il2,FAS,TG,HLA-DRB4,HLA-A,GZMB |
| Allograft rejection | HLA-DRB1,HLA-A,HLA-E,HLA-DMA,HLA-DPB1,CD40LG,IL4,Il2,IL12A,HLA-DQA2 |
| Staphylococcus aureus infection | PTAFR,HLA-DRB1,SELP,FCGR3A,MBL2,SELPLG,FCGR4,Hc,ICAM1,FCGR2B |
| Phagosome | CANX,VAMP3,TLR2,H2-Q10,MHC2DAB,HLA-DMB,ABCB3L1,ATP6V0E1,TLR4BB,CD14 |
| Asthma | IL3,HLA-DRB4,HLA-DPB1,H2-AA,HLA-DPA1,HLA-DRB5,MS4A2,CD40,PRG2,IL4 |
| Viral myocarditis | RAC3,HLA-G,MYH7,HLA-DMB,FYN,EIF4G3,RAC1,SGCB,ITGB2,HLA-DQB1 |
| Systemic lupus erythematosus | H2AFY,HIST1H2BH,HIST1H2AN,HIST1H2BE,HIST1H2AC,C8G,HIST1H2BL,H2AFJ,HIST1H2AG,HLA-DPB1 |
| Tuberculosis | IFNA1,CALM1,RIPK2,CD209C,IL23,IRAK1,Itgam&Itgb2,MRC1,CALM3,RAB7A |
Protein Function
H2-AB1 has several biochemical functions, for example, peptide antigen binding,protein antigen binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by H2-AB1 itself. We selected most functions H2-AB1 had, and list some proteins which have the same functions with H2-AB1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin protein ligase binding | TP53,RNF40,GLMN,TANK,GSK3B,ANKRD32,AICDA,UBE2NA,CUL1A,GABARAPL1 |
| peptide antigen binding | MHC1UHA,MR1,MHC1ZDA,MHC1ZKA,HLA-DQA1,HLA-B,AZGP1,HLA-DPA1,HLA-E,HLA-DRB1 |
| protein heterodimerization activity | HIST1H2BP,TBX15,IKZF4,JAM2A,TAS1R2,NR2C2,BMP2,TCF4,HIST1H2AA,IRAK1 |
| transcription factor binding | RPS3,MLXIPL,CRY1,ERCC3,KLF5,SIRT2,VDRA,HES7,MDFI,TP73 |
| protein binding | AGPAT1,ALDH18A1,OTUB1,BICC1,HNRNPL,NDUFS1,ZC3H8,CHDH,RBM10,NHLRC1 |
| protein antigen binding | EP300,KLRC2,ITGA4,KLRD1 |
| toxic substance binding | AZU1,DSG1,PHAX,Alb,CHRNA7,NEFH,EPHX2,A4GALT,ASS1,GUCY2C |
Interacting Protein
H2-AB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with H2-AB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of H2-AB1.
H2-Aa
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References
- Zemelka-Wiacek, M; Szczepanik, M; et al. Tc1-mediated contact sensitivity reaction, its mechanism and regulation. POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ 68:955-969(2014).
- Frigstad, T; Loset, GA; et al. A Public T cell Receptor Recognized by a Monoclonal Antibody Specific for the D-J Junction of the beta-chain. SCANDINAVIAN JOURNAL OF IMMUNOLOGY 78:345-351(2013).
