hdgf Protein, hepatoma-derived growth factor


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Official Full Name hepatoma-derived growth factor
Background This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. This gene was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Synonyms HDGF; hepatoma-derived growth factor; hepatoma derived growth factor (high mobility group protein 1 like); high mobility group protein 1 like; HMG1L2; HMG-1L2; high mobility group protein 1-like 2; FLJ96580; DKFZp686J1764
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • GST
    • His
    • Myc
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse HDGF-2277M Recombinant Mouse HDGF Protein (1-237 aa), His-Myc-tagged Yeast His/Myc
    Human HDGF-1052H Recombinant Human HDGF Protein, His-tagged E.coli His
    Human HDGF-27530TH Recombinant Human HDGF E.coli N/A
    Human HDGF-29209TH Recombinant Human HDGF E.coli N/A
    Human HDGF-361H Recombinant Human HDGF E.coli N/A
    Human HDGF-4658H Recombinant Human HDGF Protein, GST-tagged Wheat Germ GST
    Human HDGF-5598HCL Recombinant Human HDGF 293 Cell Lysate HEK293 N/A
    Human HDGF-620H Recombinant Human HDGF protein, His & T7-tagged E.coli His/T7
    Mouse HDGF-7539M Recombinant Mouse HDGF Protein Mammalian Cell His
    Mouse Hdgf-75M Recombinant Mouse Hdgf protein, His-tagged E.coli His
    Rat HDGF-2819R Recombinant Rat HDGF Protein Mammalian Cell His

    hdgf involved in several pathways and played different roles in them. We selected most pathways hdgf participated on our site, such as IRE1alpha activates chaperones, Metabolism of proteins, Unfolded Protein Response (UPR), which may be useful for your reference. Also, other proteins which involved in the same pathway with hdgf were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    IRE1alpha activates chaperones YIF1A; TPP1; ADD1; CXXC1; DNAJB9; KLHDC3; C19orf10; KDELR3; PDIA6; CTDSP2
    Metabolism of proteins ADAMTS3; ADAMTS1; DPP4; DOHH; IGFBP5B; CGB7; CDX2; FKBP9; TIMM8A; IGFBP2A
    Unfolded Protein Response (UPR) KLHDC3; CXXC1; CTDSP2; YIF1A; HDGF; HYOU1; DDX11; ASNA1; WIPI1; DNAJB9
    XBP1(S) activates chaperone genes SEC63; CXXC1; SERP1; YIF1A; PDIA6; DNAJB9; ASNA1; C19orf10; HDGF; FKBP14

    hdgf has several biochemical functions, for example, DNA binding, RNA polymerase II transcription corepressor activity, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by hdgf itself. We selected most functions hdgf had, and list some proteins which have the same functions with hdgf. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II transcription corepressor activity URI1; UXT; OLIG3; SIN3AA; SOX3; TLE1; CTBP1; N4BP2L2; TBX18; TCERG1
    growth factor activity CSPG5; IL11; MIA; GDF7; BMP2; IGF3; BMP7A; BMP7B; LFT2; CSF1B
    heparin binding FBLN7; MSTN; APOH; OGN; UBE4A; HRG; ADAMTS8; CCDC80; APPA; VEGFAA
    nucleotide binding UBE2NB; U2AF1; DHX33; RBFOX1L; HIPK3B; ATP1A1A.5; LTB4R; VMHC; TIA1; RAF1A
    poly(A) RNA binding RBM10; DIAP1; GTPBP4; GNL3; EBNA1BP2; SRP72; ACAA2; ISY1; NPM1; RPS27.1
    transcription corepressor binding SIX3; HDGF; RORA; NR1D1; FAM89B

    hdgf has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hdgf here. Most of them are supplied by our site. Hope this information will be useful for your research of hdgf.


    Kang, S; Xiao, G; et al. Proteomics analysis of altered cellular metabolism induced by insufficient copper level. JOURNAL OF BIOTECHNOLOGY 189:15-26(2014).
    Zhao, J; Ma, MZ; et al. Anti-HDGF Targets Cancer and Cancer Stromal Stem Cells Resistant to Chemotherapy. CLINICAL CANCER RESEARCH 19:3567-3576(2013).

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