| Official Full Name | hepatoma-derived growth factor |
| Background | This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. This gene was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
| Synonyms | HDGF; hepatoma-derived growth factor; hepatoma derived growth factor (high mobility group protein 1 like); high mobility group protein 1 like; HMG1L2; HMG-1L2; high mobility group protein 1-like 2; FLJ96580; DKFZp686J1764 |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
hdgf involved in several pathways and played different roles in them. We selected most pathways hdgf participated on our site, such as IRE1alpha activates chaperones, Metabolism of proteins, Unfolded Protein Response (UPR), which may be useful for your reference. Also, other proteins which involved in the same pathway with hdgf were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| IRE1alpha activates chaperones | YIF1A; TPP1; ADD1; CXXC1; DNAJB9; KLHDC3; C19orf10; KDELR3; PDIA6; CTDSP2 |
| Metabolism of proteins | ADAMTS3; ADAMTS1; DPP4; DOHH; IGFBP5B; CGB7; CDX2; FKBP9; TIMM8A; IGFBP2A |
| Unfolded Protein Response (UPR) | KLHDC3; CXXC1; CTDSP2; YIF1A; HDGF; HYOU1; DDX11; ASNA1; WIPI1; DNAJB9 |
| XBP1(S) activates chaperone genes | SEC63; CXXC1; SERP1; YIF1A; PDIA6; DNAJB9; ASNA1; C19orf10; HDGF; FKBP14 |
hdgf has several biochemical functions, for example, DNA binding, RNA polymerase II transcription corepressor activity, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by hdgf itself. We selected most functions hdgf had, and list some proteins which have the same functions with hdgf. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | POLE3; MEIS2B; HOXB5A; ATXN1L; TSG101; CSDC2; HSF5; RABGEF1; PTF1A; HNF4A |
| RNA polymerase II transcription corepressor activity | URI1; UXT; OLIG3; SIN3AA; SOX3; TLE1; CTBP1; N4BP2L2; TBX18; TCERG1 |
| growth factor activity | CSPG5; IL11; MIA; GDF7; BMP2; IGF3; BMP7A; BMP7B; LFT2; CSF1B |
| heparin binding | FBLN7; MSTN; APOH; OGN; UBE4A; HRG; ADAMTS8; CCDC80; APPA; VEGFAA |
| nucleotide binding | UBE2NB; U2AF1; DHX33; RBFOX1L; HIPK3B; ATP1A1A.5; LTB4R; VMHC; TIA1; RAF1A |
| poly(A) RNA binding | RBM10; DIAP1; GTPBP4; GNL3; EBNA1BP2; SRP72; ACAA2; ISY1; NPM1; RPS27.1 |
| transcription corepressor binding | SIX3; HDGF; RORA; NR1D1; FAM89B |
hdgf has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hdgf here. Most of them are supplied by our site. Hope this information will be useful for your research of hdgf.
DDX5; SRSF1; SSRP1; HDAC1; PARP1; PRKDC
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