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Official Full Name histone cluster 1, H1b
Background Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.
Synonyms HIST1H1B; histone cluster 1, H1b; H1 histone family, member 5 , H1F5, histone 1, H1b; histone H1.5; H1.5; H1; H1 histone family member 5; H15 HUMAN; H15_HUMAN; H1F5; Histone 1 H1b; Histone cluster 1 H1b; Histone H1a; MGC126630; MGC126632; histone 1, H1b; H1 histone family, member 5; H1B
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HIST1H1B-5554HCL Recombinant Human HIST1H1B 293 Cell Lysate HEK293 N/A
    Mouse HIST1H1B-7643M Recombinant Mouse HIST1H1B Protein Mammalian Cell His
    Rat HIST1H1B-2849R Recombinant Rat HIST1H1B Protein Mammalian Cell His
    Rhesus Macaque HIST1H1B-2086R Recombinant Rhesus monkey HIST1H1B Protein, His-tagged Mammalian Cell His

    hist1h1b involved in several pathways and played different roles in them. We selected most pathways hist1h1b participated on our site, such as Activation of DNA fragmentation factor, Apoptosis, Apoptosis induced DNA fragmentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with hist1h1b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activation of DNA fragmentation factor HIST1H1C; DFFA; HMGB2A; HMGB2; HIST1H1E; HIST1H1D; HIST1H1A; H1F0; HIST1H1B
    Apoptosis induced DNA fragmentation HIST1H1B; H1F0; HMGB2A; DFFA; HIST1H1A; HIST1H1D; HIST1H1E; HIST1H1C; HMGB2
    Apoptotic execution phase GAS2; DBNLA; STK24A; DBNL; HIST1H1D; CTNNB1; BMX; ADD1; DBNLB; PTBP3
    Cellular Senescence ASF1A; EP400; ACD; CBX6; HTATIP; BMI1B; SCMH1; ERF; PHC2; TINF2
    Cellular responses to stress C11orf73; HIST1H1C; PTGES3; PHC1; LAMTOR1; RNF2; RAD50; NUP35; GABARAP; HIST1H1D
    DNA Damage/Telomere Stress Induced Senescence HMGA1; HIST1H1E; HIST1H1B; TERF1; HMGA1-RS1; HIST1H1C; HIRA; TERF2IP; CABIN1; HIST1H1D
    Formation of Senescence-Associated Heterochromatin Foci (SAHF) HMGA1B; HIRA; ASF1A; HMGA1-RS1; CABIN1; HIST1H1C; HIST1H1D; UBN1; H1F0; HIST1H1B

    hist1h1b has several biochemical functions, for example, chromatin DNA binding, histone deacetylase binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by hist1h1b itself. We selected most functions hist1h1b had, and list some proteins which have the same functions with hist1h1b. You can find most of the proteins on our site.

    Function Related Protein
    chromatin DNA binding NOTCH1; GRHL1; VAX2; RELA; GRHL2; H1F0; EP300; ACTN4; RUVBL2; GRHL3
    histone deacetylase binding NCOR1; KAT2A; RUNX2; NKX2-5; HEY2; NRIP1; CBX5; NIPBL; RAD9; TFAP4
    poly(A) RNA binding EBNA1BP2; TRMT6; ZFR; SUPT6H; SRP68; DNTTIP2; ALKBH5; RPL26; GM5506; WDR36

    hist1h1b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hist1h1b here. Most of them are supplied by our site. Hope this information will be useful for your research of hist1h1b.

    VCAM1; ssrna_ug

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