| Official Full Name | histone cluster 1, H1b |
| Background | Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. |
| Synonyms | HIST1H1B; histone cluster 1, H1b; H1 histone family, member 5 , H1F5, histone 1, H1b; histone H1.5; H1.5; H1; H1 histone family member 5; H15 HUMAN; H15_HUMAN; H1F5; Histone 1 H1b; Histone cluster 1 H1b; Histone H1a; MGC126630; MGC126632; histone 1, H1b; H1 histone family, member 5; H1B |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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hist1h1b involved in several pathways and played different roles in them. We selected most pathways hist1h1b participated on our site, such as Activation of DNA fragmentation factor, Apoptosis, Apoptosis induced DNA fragmentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with hist1h1b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Activation of DNA fragmentation factor | HIST1H1C; DFFA; HMGB2A; HMGB2; HIST1H1E; HIST1H1D; HIST1H1A; H1F0; HIST1H1B |
| Apoptosis | BAXA; FASLG; CAPN1; CAPN2; PPP3CA; IRF4A; CAPN1A; TNFSF10; HRK; PPP3CCA |
| Apoptosis induced DNA fragmentation | HIST1H1B; H1F0; HMGB2A; DFFA; HIST1H1A; HIST1H1D; HIST1H1E; HIST1H1C; HMGB2 |
| Apoptotic execution phase | GAS2; DBNLA; STK24A; DBNL; HIST1H1D; CTNNB1; BMX; ADD1; DBNLB; PTBP3 |
| Cellular Senescence | ASF1A; EP400; ACD; CBX6; HTATIP; BMI1B; SCMH1; ERF; PHC2; TINF2 |
| Cellular responses to stress | C11orf73; HIST1H1C; PTGES3; PHC1; LAMTOR1; RNF2; RAD50; NUP35; GABARAP; HIST1H1D |
| DNA Damage/Telomere Stress Induced Senescence | HMGA1; HIST1H1E; HIST1H1B; TERF1; HMGA1-RS1; HIST1H1C; HIRA; TERF2IP; CABIN1; HIST1H1D |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | HMGA1B; HIRA; ASF1A; HMGA1-RS1; CABIN1; HIST1H1C; HIST1H1D; UBN1; H1F0; HIST1H1B |
hist1h1b has several biochemical functions, for example, chromatin DNA binding, histone deacetylase binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by hist1h1b itself. We selected most functions hist1h1b had, and list some proteins which have the same functions with hist1h1b. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chromatin DNA binding | NOTCH1; GRHL1; VAX2; RELA; GRHL2; H1F0; EP300; ACTN4; RUVBL2; GRHL3 |
| histone deacetylase binding | NCOR1; KAT2A; RUNX2; NKX2-5; HEY2; NRIP1; CBX5; NIPBL; RAD9; TFAP4 |
| poly(A) RNA binding | EBNA1BP2; TRMT6; ZFR; SUPT6H; SRP68; DNTTIP2; ALKBH5; RPL26; GM5506; WDR36 |
hist1h1b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hist1h1b here. Most of them are supplied by our site. Hope this information will be useful for your research of hist1h1b.
VCAM1; ssrna_ug
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