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Official Full Name HIST1H4E histone cluster 1, H4e [ Homo sapiens ]
Background Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Synonyms histone cluster 1, H4e; 4790; Ensembl:ENSG00000198518; histone H4; histone 1, H4e; H4 histone family, member J; H4/j; H4FJ
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • Tag :
    • GST
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HIST1H4E-13798H Recombinant Human HIST1H4E, GST-tagged E.coli GST
    Human HIST1H4E-5525HCL Recombinant Human HIST1H4E 293 Cell Lysate HEK293 N/A

    hist1h4e involved in several pathways and played different roles in them. We selected most pathways hist1h4e participated on our site, such as Alcoholism, Viral carcinogenesis, Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with hist1h4e were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Alcoholism HIST1H2BE; CRH; HDAC9; HDAC1; HIST2H4; H2AFZ; H2AFX; GM14479; HIST2H2AC; HIST3H2A
    Systemic lupus erythematosus HIST1H2BK; HIST1H4C; HLA-DRB3; CD28; C8A; HIST1H2BA; HIST1H3C; FCGR4; FCGR2A; HIST2H4A

    hist1h4e has several biochemical functions, for example, DNA binding, histone binding, histone demethylase activity (H4-K20 specific). Some of the functions are cooperated with other proteins, some of the functions could acted by hist1h4e itself. We selected most functions hist1h4e had, and list some proteins which have the same functions with hist1h4e. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding ZNF324; BRPF1; IKZF1; ZFP422; LHX1A; ZNF776; NR6A1B; NR4A2B; HOMEZB; ZMAT2
    histone binding HIST1H4C; HIST1H4D; NAP1L2; HIST1H3A; HIST1H4L; HIST3H3; HIST1H4J; PHF21A; PIH1D1; ANP32E
    histone demethylase activity (H4-K20 specific) HIST4H4; HIST1H4A; HIST1H4B; HIST1H4I; HIST1H4H; HIST2H4A; PHF8; HIST1H4F; HIST1H4L; HIST1H4K
    poly(A) RNA binding RPS3A; RPL11; HSPB1; AHNAK; RPS13; PYDC3; FAM103A1; SRSF2; RPL17; RPS21
    protein binding KITLG; DDB2; SETD7; GNA14; RAPGEF3; VPS24; SPHK1; C4orf46; NCOR1; SALL2
    protein domain specific binding YWHAH; ST13; HIST1H4D; CASP2; TJP2; MYH9; MPP7; SNCA; WNT1; XPA
    protein heterodimerization activity Defa-rs7; SNX6; TGFB1; LIFR; ITGB1A; HIST1H3F; MCL1B; Itgam&Itgb2; ABCG1; BCL2

    hist1h4e has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hist1h4e here. Most of them are supplied by our site. Hope this information will be useful for your research of hist1h4e.


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