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HNRNPR

  • Official Full Name

    heterogeneous nuclear ribonucleoprotein R

  • Overview

    This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
  • Synonyms

    HNRNPR; heterogeneous nuclear ribonucleoprotein R; HNRPR; hnRNP R; hnRNP-R;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Wheat Germ
  • Fc|His
  • GST
  • His
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HNRNPR-4906H Recombinant Human HNRNPR Protein, GST-tagged Wheat Germ GST
Human HNRNPR-8649H Recombinant Human HNRNPR, His-GST tagged Insect Cell Fc/His
Human HNRNPR-001HCL Recombinant Human HNRNPR cell lysate Insect Cell N/A
Human HNRNPR-5385H Recombinant Human HNRNPR Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HNRNPR-1845H Recombinant Human HNRNPR Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human HNRNPR-3618HF Recombinant Full Length Human HNRNPR Protein, GST-tagged In Vitro Cell Free System GST 633 amino acids
Human HNRNPR-1767H Recombinant Human HNRNPR Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HNRNPR-3238H Recombinant Human HNRNPR protein(Ala2-Lys636), His&GST-tagged Insect Cells N-His&GST Ala2-Lys636
Mouse Hnrnpr-3421M Recombinant Mouse Hnrnpr Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish HNRNPR-12598Z Recombinant Zebrafish HNRNPR Mammalian Cell His
Chicken HNRNPR-1454C Recombinant Chicken HNRNPR Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HNRNPR involved in several pathways and played different roles in them. We selected most pathways HNRNPR participated on our site, such as Gene Expression, Processing of Capped Intron-Containing Pre-mRNA, mRNA Splicing, which may be useful for your reference. Also, other proteins which involved in the same pathway with HNRNPR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Gene ExpressionSKI;ZNF493;SNAPC2;ZNF706;IPO8;ZIM3;BCAS2;NRBF2B;HENMT1
Processing of Capped Intron-Containing Pre-mRNAHNRNPL2;THOC4;PTBP1;TTC6;HNRNPA2B1;HNRNPA0A;DNAJC8;METTL3;SF3A1
mRNA SplicingHNRNPA0B;PDCD7;HNRNPL;HNRNPA0L;SFRS3A;SF3A3;SF3B2;HNRNPF;CCAR1
mRNA Splicing - Major PathwayCD2BP2;HNRNPL2;HNRPL;PTBP1;HNRNPF;TXNL4A;PRPF8;SFRS3A;DNAJC8
mRNA processingZFP346;RBM12B2;PRPF4B;OASL2;SF3B4;CD2BP2;SPOP;SF3B2;SUGP2

HNRNPR has several biochemical functions, for example, RNA binding, nucleotide binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HNRNPR itself. We selected most functions HNRNPR had, and list some proteins which have the same functions with HNRNPR. You can find most of the proteins on our site.

Function Related Protein
RNA bindingSARS;CTIF;RBM46;RBMS2;EIF3K;EXOSC5;CNOT6;IGF2BP2A;KIAA0907
nucleotide bindingTDRD12;RAB1BA;ATAD1B;DCLK3;RBM42;NCBP2;SAFB2;DNAHC8;HNRNPA1A
poly(A) RNA bindingFAM103A1;ISY1;SLC3A2;HARS2;ZFP326;NXF3;EIF3E;DDX55;ZNF622
protein bindingGRK5;RHEB;KIAA0408;TMEM185A;PRC1;TNNC2;RXRA;RIPK1L;GATA5

HNRNPR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HNRNPR here. Most of them are supplied by our site. Hope this information will be useful for your research of HNRNPR.

YBX1; PRMT1; KHDRBS2; ssrna_cg; ESR1; TOP1

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