Hsd3b6

  • Official Full Name

    hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6

  • Synonyms

    Hsd3b1

Recombinant Proteins

  • Rat
  • Mouse
  • Mus musculus
  • Mammalian Cells
  • HEK293
  • E.coli
  • His
  • Avi
  • Fc

    Involved Pathway

    Hsd3b6 involved in several pathways and played different roles in them. We selected most pathways Hsd3b6 participated on our site, such as Steroid hormone biosynthesis,Metabolic pathways,Ovarian steroidogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with Hsd3b6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Steroid hormone biosynthesis UGT1A7C,HSD17B2,PPP1R2,SRD5A2A,CYP2D26,CYP2C45,UGT1A6,CYP2C39,UGT1A6A,HSD3B4
    Ovarian steroidogenesis LDLR,STAR,INSR,HSD17B1,GDF9,PRKACB,PTGS2,INS1,LHCGR,INS
    Metabolic pathways NDUFA4,ACSS2L,NAGLU,ALDH18A1,GCDHB,OGDHA,EXT1B,PLA2G4A,B3GNT2B,HSD17B12A
    Aldosterone synthesis and secretion GNAS,PRKACB,CREB3L2,CAMK2D,ADCY8,CYP11B2,STAR,NR4A2,PRKACA,PDE2A

    Protein Function

    Hsd3b6 has several biochemical functions, for example, (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity,(R)-2-hydroxyglutarate dehydrogenase activity,(R)-2-hydroxyisocaproate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Hsd3b6 itself. We selected most functions Hsd3b6 had, and list some proteins which have the same functions with Hsd3b6. You can find most of the proteins on our site.

    Function Related Protein
    aldo-keto reductase (NADP) activity AKR1C3,AKR1C4,HSD11B1LA,MIOX,AKR1B1,SDR42E1,AKR1C6,KCNAB2,AKR1B10,SPR
    very long-chain-3-hydroxyacyl-CoA dehydrogenase activity AKR1C6,SDR42E1,AKR1C21,HSD3B5,H2-KE6,HSD11B1LA,SDR16C6
    D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity HSD11B1LA,HSD3B5,SDR16C6,AKR1C6,AKR1C21,H2-KE6,SDR42E1
    3-beta-hydroxy-delta5-steroid dehydrogenase activity HSD3B5,HSD3B1,HSD3B4,SDR42E1,NSDHL,HSD3B7,HSD3B2
    epoxide dehydrogenase activity AKR1C6,H2-KE6,HSD11B1LA,SDR42E1,HSD3B5,AKR1C21,SDR16C6
    isomerase activity PBLD1,PPIAB,PPIFA,TPI1A,ITPK1A,FKBP1AA,PGAM1B,PBLD2,HSD17B4,GSBP9
    catalytic activity AGXT2,ALDOCB,PHYKPL,DIP2BA,FH1,HADHAA,QDPRB1,LDHBB,PFKFB4L,SYN2B
    steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor HSD3B5,HSD11B1LA,SDR42E1,SDR16C6,AKR1C21,H2-KE6,AKR1C6
    D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity H2-KE6,HSD3B5,SDR16C6,AKR1C21,HSD11B1LA,SDR42E1,AKR1C6

    Interacting Protein

    Hsd3b6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Hsd3b6 here. Most of them are supplied by our site. Hope this information will be useful for your research of Hsd3b6.

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