Hsd3b6

  • Official Full Name

    hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6

  • Synonyms

    Hsd3b1

Recombinant Proteins

  • Rat
  • Mouse
  • Mus musculus
  • Mammalian Cells
  • HEK293
  • E.coli
  • His
  • Avi
  • Fc

    Involved Pathway

    Hsd3b6 involved in several pathways and played different roles in them. We selected most pathways Hsd3b6 participated on our site, such as Steroid hormone biosynthesis,Metabolic pathways,Ovarian steroidogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with Hsd3b6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolic pathways ACO2,PLA2G2E,PIP5K1A,GCLC,ALDH18A1,ACSL1B,INPP4AB,AKR1B7,SYNJ2,AOC2
    Steroid hormone biosynthesis CYP2C70,AKR1D1,CYP3A65,CYP2C50,CYP1A,CYP2C39,AKR1C3,UGT2B7,H2-KE6,UGT5G1
    Ovarian steroidogenesis HSD17B1,GNAS,IGF1R,STAR,LHCGR,HSD3B4,LDLR,FSHB,PRKACA,SCARB1
    Aldosterone synthesis and secretion ADCY6,ORAI1,CREB3L3,PRKACB,STAR,CREB3,HSD3B5,CREB3L2,PLCB4,CREB3L1

    Protein Function

    Hsd3b6 has several biochemical functions, for example, (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity,(R)-2-hydroxyglutarate dehydrogenase activity,(R)-2-hydroxyisocaproate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Hsd3b6 itself. We selected most functions Hsd3b6 had, and list some proteins which have the same functions with Hsd3b6. You can find most of the proteins on our site.

    Function Related Protein
    D-xylose:NADP reductase activity HSD11B1LA,SDR16C6,AKR1C6,SDR42E1,AKR1C21,HSD3B5,H2-KE6
    dihydrotestosterone 17-beta-dehydrogenase activity H2-KE6,HSD3B5,AKR1C6,SDR16C6,AKR1C21,SDR42E1,AKR1C3,HSD11B1LA
    5-exo-hydroxycamphor dehydrogenase activity AKR1C21,AKR1C6,HSD11B1LA,SDR42E1,SDR16C6,H2-KE6,HSD3B5
    aldo-keto reductase (NADP) activity KCNAB1,AKR1C3,HSD3B5,AKR7A3,AKR1B10,SDR42E1,H2-KE6,MIOX,CYB5A,AKR1C21
    (R)-2-hydroxyglutarate dehydrogenase activity HSD3B5,SDR16C6,SDR42E1,H2-KE6,AKR1C6,AKR1C21,HSD11B1LA,D2HGDH
    mevaldate reductase activity H2-KE6,SDR42E1,SDR16C6,AKR1C21,HSD11B1LA,AKR1C6,HSD3B5
    oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor HMGCRB,MDH1B,LDHBB,HMGCRA,GPD1B,LDHBA,GPD1C,MDH1AA,CTBP2L,GRHPRB
    isocitrate dehydrogenase activity SDR42E1,SDR16C6,AKR1C6,HSD11B1LA,HSD3B5,H2-KE6,AKR1C21
    steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor SDR16C6,AKR1C21,HSD3B5,H2-KE6,AKR1C6,HSD11B1LA,SDR42E1

    Interacting Protein

    Hsd3b6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Hsd3b6 here. Most of them are supplied by our site. Hope this information will be useful for your research of Hsd3b6.

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