Hsd3b6

  • Official Full Name

    hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6
  • Synonyms

    Hsd3b1

Recombinant Proteins

  • Rat
  • Mouse
  • Mammalian Cells
  • HEK293
  • E.coli
  • His
  • Avi
  • Fc

    Involved Pathway

    Hsd3b6 involved in several pathways and played different roles in them. We selected most pathways Hsd3b6 participated on our site, such as Steroid hormone biosynthesis,Metabolic pathways,Ovarian steroidogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with Hsd3b6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ovarian steroidogenesis BMP15,HSD17B1,HSD17B2,FSHR,Adcy4,PLA2G4C,LDLR,HSD3B2,STAR,INS
    Aldosterone synthesis and secretion CYP11A1,ADCY3,LDLR,ADCY8,CAMK2G,GNAS,CACNA1G,LIPE,PRKD2,NPR1
    Steroid hormone biosynthesis UGT2A2,AKR1D1,CYP2D10,HSD17B12A,SULT2B1,UGT2B7,CYP2B19,UGT1A4,UGT5G1,UGT1A6B
    Metabolic pathways NDUFB3,NOS2B,GMPPA,ATP6V1E2,ATP6V0D2,COX17,ATP5G1,ALDH2,GM5506,UCK2

    Protein Function

    Hsd3b6 has several biochemical functions, for example, (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity,(R)-2-hydroxyglutarate dehydrogenase activity,(R)-2-hydroxyisocaproate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Hsd3b6 itself. We selected most functions Hsd3b6 had, and list some proteins which have the same functions with Hsd3b6. You can find most of the proteins on our site.

    Function Related Protein
    steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor HSD11B1LA,SDR42E1,H2-KE6,AKR1C21,AKR1C6,HSD3B5,SDR16C6
    oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor LDHBA,GRHPRB,GPD1C,GPD1B,CTBP1,GRHPRA,CTBP2A,HSD3B5,GPD1,CTBP2
    C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity AKR1C6,HSD11B1LA,H2-KE6,SDR16C6,SDR42E1,HSD3B5,AKR1C21
    (R)-2-hydroxyisocaproate dehydrogenase activity AKR1C6,AKR1C21,SDR42E1,SDR16C6,HSD3B5,HSD11B1LA,H2-KE6
    catalytic activity GOT2B,PPM1BA,PPM1LB,Amy1,LGI1A,ACAA1A,SLC3A2B,SCP2A,CKBA,TGM3
    acetoin dehydrogenase activity HSD3B5,AKR1C6,SDR42E1,HSD11B1LA,SDR16C6,AKR1C21,H2-KE6
    L-arabinose 1-dehydrogenase (NADP+) activity AKR1C6,H2-KE6,SDR42E1,SDR16C6,HSD11B1LA,AKR1C21,HSD3B5
    gluconate dehydrogenase activity HSD3B5,AKR1C21,H2-KE6,SDR16C6,SDR42E1,AKR1C6,HSD11B1LA
    D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity SDR42E1,AKR1C6,HSD11B1LA,SDR16C6,AKR1C21,HSD3B5,H2-KE6

    Interacting Protein

    Hsd3b6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Hsd3b6 here. Most of them are supplied by our site. Hope this information will be useful for your research of Hsd3b6.

    Resources

    References

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