Hsd3b6
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Official Full Name
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6
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Synonyms
Hsd3b1;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- E.coli expression system
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- Involved Pathway
- Protein Function
- Interacting Protein
Hsd3b6 involved in several pathways and played different roles in them. We selected most pathways Hsd3b6 participated on our site, such as Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with Hsd3b6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Steroid hormone biosynthesis | HSD3B1;HSD17B12;HSD3B4;UGT1A6A;SULT1E1;CYP2C45;UGT2B7;UGT1A3;CYP3A7 |
| Metabolic pathways | AK7;AGMAT;ATIC;UPP1;ALDH4A1;POLE3;INPP5KA;UCK2;CBS |
| Ovarian steroidogenesis | INSR;PRKACA;STAR;AKR1C3;BMP6;HSD17B7;PRKACB;ALOX5;PLA2G4C |
| Aldosterone synthesis and secretion | SCARB1;ADCY8;SLC14A2;AGTR1;GNAS;CAMK1G;CALM2;NR4A2;STAR |
Hsd3b6 has several biochemical functions, for example, (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity, (R)-2-hydroxyglutarate dehydrogenase activity, (R)-2-hydroxyisocaproate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Hsd3b6 itself. We selected most functions Hsd3b6 had, and list some proteins which have the same functions with Hsd3b6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity | H2-KE6;AKR1C21;SDR42E1;AKR1C6;HSD11B1LA;SDR16C6;HSD3B5;HSD3B6 |
| (R)-2-hydroxyglutarate dehydrogenase activity | D2HGDH;AKR1C6;AKR1C21;H2-KE6;HSD3B6;HSD11B1LA;HSD3B5;SDR42E1;SDR16C6 |
| (R)-2-hydroxyisocaproate dehydrogenase activity | HSD11B1LA;HSD3B5;H2-KE6;SDR16C6;AKR1C6;AKR1C21;HSD3B6;SDR42E1 |
| 2-hydroxytetrahydrofuran dehydrogenase activity | HSD3B6;SDR16C6;AKR1C6;SDR42E1;AKR1C21;H2-KE6;HSD11B1LA;HSD3B5 |
| 3-beta-hydroxy-delta5-steroid dehydrogenase activity | SDR42E1;HSD3B2;HSD3B1;HSD3B5;HSD3B6;NSDHL;HSD3B4;HSD3B7 |
| 3-hydroxymenthone dehydrogenase activity | AKR1C21;HSD11B1LA;SDR42E1;HSD3B6;HSD3B5;AKR1C6;H2-KE6;SDR16C6 |
| 3-ketoglucose-reductase activity | AKR1C21;SDR42E1;AKR1C6;HSD11B1LA;H2-KE6;SDR16C6;HSD3B6;HSD3B5 |
| 5-exo-hydroxycamphor dehydrogenase activity | AKR1C6;AKR1C21;HSD3B5;SDR16C6;HSD11B1LA;HSD3B6;H2-KE6;SDR42E1 |
| C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity | HSD3B5;AKR1C6;AKR1C21;SDR16C6;HSD3B6;H2-KE6;SDR42E1;HSD11B1LA |
| D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity | HSD3B6;SDR42E1;SDR16C6;H2-KE6;HSD11B1LA;AKR1C21;AKR1C6;HSD3B5 |
| D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity | AKR1C6;HSD3B6;SDR16C6;SDR42E1;AKR1C21;HSD3B5;H2-KE6;HSD11B1LA |
| D-xylose:NADP reductase activity | SDR42E1;AKR1C21;HSD3B6;AKR1C6;HSD3B5;SDR16C6;HSD11B1LA;H2-KE6 |
| L-arabinose 1-dehydrogenase (NADP+) activity | HSD3B6;SDR16C6;AKR1C6;AKR1C21;HSD11B1LA;SDR42E1;HSD3B5;H2-KE6 |
| L-arabinose:NADP reductase activity | SDR16C6;H2-KE6;HSD11B1LA;AKR1C6;AKR1C21;SDR42E1;HSD3B5;HSD3B6 |
| L-xylulose reductase (NAD+) activity | H2-KE6;HSD3B5;AKR1C6;SDR42E1;SDR16C6;HSD3B6;AKR1C21;HSD11B1LA |
| acetoin dehydrogenase activity | HSD11B1LA;HSD3B5;HSD3B6;SDR16C6;H2-KE6;AKR1C21;AKR1C6;SDR42E1 |
| aldo-keto reductase (NADP) activity | AKR1B10;AKR1C3;MIOX;AKR1C4;HSD3B5;HSD11B1LA;AKR1C6;SPR;AKR1B1 |
| catalytic activity | HSD3B6;AADAC;TM9SF1;ALP3;ACSM2;MOXD2;GNSA;ACSL1A;LDHBB |
| dihydrotestosterone 17-beta-dehydrogenase activity | AKR1C3;SDR42E1;H2-KE6;AKR1C21;HSD3B5;HSD11B1LA;AKR1C6;HSD3B6;SDR16C6 |
| epoxide dehydrogenase activity | SDR42E1;SDR16C6;HSD3B6;H2-KE6;AKR1C21;HSD11B1LA;HSD3B5;AKR1C6 |
| gluconate dehydrogenase activity | AKR1C6;SDR16C6;HSD3B6;AKR1C21;HSD11B1LA;SDR42E1;HSD3B5;H2-KE6 |
| isocitrate dehydrogenase activity | AKR1C21;HSD3B5;SDR16C6;SDR42E1;H2-KE6;HSD3B6;HSD11B1LA;AKR1C6 |
| isomerase activity | GPIA;PDIP5;HSD3B6;PTGESL;TOP1L;PPIAB;TPI1A;PBLD;HMGCS1 |
| mevaldate reductase activity | HSD3B5;HSD11B1LA;H2-KE6;SDR16C6;SDR42E1;AKR1C21;AKR1C6;HSD3B6 |
| oxidoreductase activity | HEPHL1;ETFA;GFOD1;LDHBA;RNLS;DHRS11A;RETSATL;DAO.2;CYP2K19 |
| oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | CTBP2;GRHPRA;CTBP2L;LDHBA;GPD1C;CTBP2A;HMGCRB;GPD1;GPD1A |
| phenylcoumaran benzylic ether reductase activity | SDR16C6;H2-KE6;HSD3B6;HSD3B5;AKR1C21;HSD11B1LA;SDR42E1;AKR1C6 |
| steroid dehydrogenase activity | HSD3B5;AKR1C6;HSD3B6;AKR1C21;SDR42E1;HSD11B1LA;HSD17B11;H2-KE6;SDR16C6 |
| steroid dehydrogenase activity, acting on the CH-CH group of donors | HSD3B6;SDR16C6;HSD3B5;SDR42E1;HSD11B1LA;AKR1C6;H2-KE6;AKR1C21 |
| steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | SDR42E1;HSD3B6;AKR1C6;H2-KE6;SDR16C6;AKR1C21;HSD3B5;HSD11B1LA |
| steroid delta-isomerase activity | HSD3B1;EBP;HSD3B2;HSD3B6 |
| very long-chain-3-hydroxyacyl-CoA dehydrogenase activity | HSD3B5;HSD11B1LA;AKR1C6;H2-KE6;SDR42E1;AKR1C21;SDR16C6;HSD3B6 |
Hsd3b6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Hsd3b6 here. Most of them are supplied by our site. Hope this information will be useful for your research of Hsd3b6.
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