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Official Full Name 5-hydroxytryptamine (serotonin) receptor 3, family member C
Background The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3.
Synonyms HTR3C; 5-hydroxytryptamine (serotonin) receptor 3, family member C; 5-hydroxytryptamine receptor 3C; 5 HT3 C; 5 HT3C; 5 hydroxytryptamine (serotonin) receptor 3, family member C; 5 hydroxytryptamine receptor 3 subunit C; 5 hydroxytryptamine receptor 3C; Serotonin receptor 3C; 5-HT3C; 5-HT3-C; 5-hydroxytryptamine receptor 3 subunit C
    • Species :
    • Human
    • Source :
    • HEK293
    • Tag :
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HTR3C-5333HCL Recombinant Human HTR3C 293 Cell Lysate HEK293 N/A

    htr3c involved in several pathways and played different roles in them. We selected most pathways htr3c participated on our site, such as Ion channel transport, Ligand-gated ion channel transport, Serotonergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with htr3c were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ion channel transport WNK1; ASPH; CLCN4; TTYH1; BEST4; CLCN5; TRPM6; CLCN7; ATP1A1A.3; CLCN1
    Ligand-gated ion channel transport GLRBA; HTR3C; GABRR2A; ARHGEF9
    Serotonergic synapse GNG10; NRAS; GNG12; GNG11; ITPR3; HTR3C; PLA2G4D; ALOX12E; ITPR1; CYP2C50
    Transmembrane transport of small molecules AQP10B; SLC9B2; ATP13A; CLCA1; SLC1A4; RHCG; SLC35A2; SLC26A3.1; ANKHA; TRPC4A

    htr3c has several biochemical functions, for example, NOT contributes_to acetylcholine binding, NOT contributes_to acetylcholine receptor activity, NOT contributes_to acetylcholine-activated cation-selective channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by htr3c itself. We selected most functions htr3c had, and list some proteins which have the same functions with htr3c. You can find most of the proteins on our site.

    Function Related Protein
    NOT contributes_to acetylcholine binding HTR3E; HTR3C; HTR3A; HTR3B
    NOT contributes_to acetylcholine receptor activity HTR3B; HTR3E; HTR3A; HTR3C
    NOT contributes_to acetylcholine-activated cation-selective channel activity HTR3C; HTR3A; HTR3E; HTR3B
    protein binding MAP2K3; ATP6V1C1; PDCL; RAD9B; PPIC; HMGB4; CTC1; GAGE1; EPHB6; DIS3L
    serotonin receptor activity HTR1B; HTR7; HTR2CL1; HTR5AL; HTR3B; HTR5A; HTR3E; HTR1F; HTR1E; HTR2B
    serotonin-activated cation-selective channel activity HTR3B; HTR3A; HTR3C; HTR3E

    htr3c has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with htr3c here. Most of them are supplied by our site. Hope this information will be useful for your research of htr3c.


    Lu, R; Alioua, A; et al. c-Src tyrosine kinase, a critical component for 5-HT(2A) receptor-mediated contraction in rat aorta. JOURNAL OF PHYSIOLOGY-LONDON 586:3855-3869(2008).
    Yoder, EJ; Tamir, H; et al. 5-Hydroxytryptamine(2A) receptors on cultured rat Schwann cells. GLIA 17:15-27(1996).

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