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Official Full Name 5-hydroxytryptamine (serotonin) receptor 6
Background Serotonin 5-HT6 receptors are located primarily in the striatum, olfactory tubercles, nucleus accumbens and hippocampus. Functions of 5-HT6 receptors include modulation of cholinergic and dopaminergic neurotransmission, and they have a role in spatial learning and memory. The human 5-HT6 receptor gene has been localized to chromosome 1 (1p35-36).
Synonyms HTR6; 5-hydroxytryptamine (serotonin) receptor 6; 5-hydroxytryptamine receptor 6; 5 HT 6; 5 HT6; 5 hydroxytryptamine 6 receptor; 5 hydroxytryptamine receptor 6; 5-HT-6; 5-HT6; 5HT 6; 5HT6R_HUMAN; HTR 6; Serotonin receptor 6
    • Species :
    • Chicken
    • Human
    • Rat
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HTR6-5331HCL Recombinant Human HTR6 293 Cell Lysate HEK293 N/A
    Rat HTR6-2970R Recombinant Rat HTR6 Protein Mammalian Cell His
    Chicken HTR6-4069C Recombinant Chicken HTR6 Mammalian Cell His

    htr6 involved in several pathways and played different roles in them. We selected most pathways htr6 participated on our site, such as Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with htr6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Calcium signaling pathway PRKCG; EGFRA; P2RX3; CAMK2A; ATP2A3; BDKRB1; ATP2A2; CALML3; PRKCA; SPHK1
    cAMP signaling pathway PDE4C; GHRL; NPY1R; FSHR; PLN; CALM3; MAPK9; FSHB; FXYD2; HCAR3
    Neuroactive ligand-receptor interaction PRL; GRM1; GLRA1; VIPR1; SSTR1; CHRNA1; TAAR8B; HRH4; F2; AVPR1B
    Serotonergic synapse HTR2A; GNG13; PRKACA; HTR5A; HTR1A; HTR4; HTR1B; GNB1; KCND2; TPH1

    htr6 has several biochemical functions, for example, histamine receptor activity, protein binding, serotonin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by htr6 itself. We selected most functions htr6 had, and list some proteins which have the same functions with htr6. You can find most of the proteins on our site.

    Function Related Protein
    histamine receptor activity HRH3; HRH2; HRH1; HRH4; HTR6
    protein binding SPRR2A; MST1; TRIM11; THAP8; SPRY1; DDL-2; STAU1; PPP4R2; RNF182; MID1
    serotonin receptor activity HTR5AL; HTR1B; HTR3E; HTR3B; HTR1AB; HTR2B; HTR7; HTR5A; HTR2A; HTR1E

    htr6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with htr6 here. Most of them are supplied by our site. Hope this information will be useful for your research of htr6.

    FYN; serotonin; lsd-lysergic acid diethylamide; fyn_crigr_protein

    Hiram, R; Rizcallah, E; et al. Resolvin D1 reverses reactivity and Ca2+ sensitivity induced by ET-1, TNF-alpha, and IL-6 in the human pulmonary artery. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 307:H1547-H1558(2014).
    Ivanenkov, YA; Majouga, AG; et al. Computational approaches to the design of novel 5-HT6R ligands. REVIEWS IN THE NEUROSCIENCES 25:451-467(2014).

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