IFIT2
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Official Full Name
interferon-induced protein with tetratricopeptide repeats 2 -
Overview
Interferon-induced protein with tetratricopeptide repeats 2 is a protein that in humans is encoded by the IFIT2 gene. -
Synonyms
IFIT2;interferon-induced protein with tetratricopeptide repeats 2;cig42;G10P2;GARG 39;Glucocorticoid attenuated response gene 39;IFI 54;IFI 54K;IFI-54K;IFI54;IFIT 2;IFIT-2;IFIT2_HUMAN;Interferon induced 54 kDa protein;Interferon induced protein 54;Interferon induced protein with tetratricopeptide repeats 2;Interferon, alpha inducible protein (MW 54kD);Interferon-induced 54 kDa protein;ISG 54 K;ISG 54K;ISG-54 K;ISG54;GARG-39;glucocorticoid-attenuated response gene 39 protein;AV302338
Recombinant Proteins
- Rhesus macaque
- Mouse
- Human
- Mammalian Cells
- HEK293
- His
- Non
- DDK
- Myc
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| IFIT2-2202R | Recombinant Rhesus monkey IFIT2 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| IFIT2-8015M | Recombinant Mouse IFIT2 Protein | Mammalian Cells | Mouse | His |
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| IFIT2-5287HCL | Recombinant Human IFIT2 293 Cell Lysate | HEK293 | Human | Non |
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| Ifit2-1216M | Recombinant Mouse Ifit2 Protein, MYC/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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| IFIT2-2023R | Recombinant Rhesus Macaque IFIT2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | Avi&Fc&His |
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| IFIT2-2023R-B | Recombinant Rhesus Macaque IFIT2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| IFIT2-4433M | Recombinant Mouse IFIT2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| IFIT2-4433M-B | Recombinant Mouse IFIT2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
IFIT2 involved in several pathways and played different roles in them. We selected most pathways IFIT2 participated on our site, such as Cytokine Signaling in Immune system,Immune System,Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFIT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Immune System | CD300LG,TRIM69,TRIM8,TRIM5,LILRA2,DEFB121,TRAF7,IFIT12,BTR02,IRF6 |
| Type II interferon signaling (IFNG) | Ifna,REG1A,IFI6,GBP1 |
| Cytokine Signaling in Immune system | CSH1,ADAR,IRAK3,KLB,USP18,IFI35,JAK3,FGF20A,TNFRSF13C,DUSP1 |
| Interferon alpha/beta signaling | IFI6,SAMHD1,OASL,IFIT3,ISG20,BST2,IRF6,IRF2,IFI35,GBP2 |
| Interferon Signaling | TRIM68,IFIT12,GBP6,IFIT3,IFIT11,IFI27,XAF1,TRIM38,TRIM14,EIF4G2A |
Protein Function
IFIT2 has several biochemical functions, for example, poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFIT2 itself. We selected most functions IFIT2 had, and list some proteins which have the same functions with IFIT2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | TBL3,CALR,NOL6,RPS27.2,MRPS23,GSPT2,ZCCHC17,C1orf53,RPL36A,YARS2 |
| protein binding | NVL,HIST1H1A,ZNF131,RBCK1,PHC2,NOS2,SERPINA5,CXCL9,FOXP4,FAM54A |
Interacting Protein
IFIT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFIT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFIT2.
IFIT1;IFIT3;HNRNPDL;DNAJA2;RPLP1;SNRPB2;SNRNP70;SNRPA;SNRPC;HNRNPA1;SNRPA1;DBT
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References
- Serrano-Fernandez, P; Moller, S; et al. Time course transcriptomics of IFNB1b drug therapy in multiple sclerosis. AUTOIMMUNITY 43:172-178(2010).
- Vural, B; Demirkan, A; et al. Seroreactivity against PTEN-induced putative kinase 1 (PINK1) in Turkish patients with Behcet's disease. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 27:S67-S72(2009).
