IL36B
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Official Full Name
interleukin 36, beta
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Overview
The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. -
Synonyms
2310043N20Rik; Family of interleukin 1 eta; FIL1; FIL1 (ETA); FIL1 eta; FIL1H; FILI-(ETA); IL 1F8; IL 1F8 (FIL1 eta; IL 1H2; IL-1 eta; IL-1F8; IL-1H2; IL1 ETA; IL1F8; IL1F8 (Canonical product IL 1F8a); IL1F8_HUMAN; IL1H2; IL36B; Interleukin 1 family, member 8; Interleukin 1 family, member 8 (eta); Interleukin 1 homolog 2; Interleukin 1 Superfamily e; Interleukin 36 beta; Interleukin-1 eta; Interleukin-1 family member 8; Interleukin-1 homolog 2; MGC126880; MGC126882; OTTMUSP00000012797; RP23-176J12.1; IL1-ETA; FIL1-(ETA);
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- Human Cells
- GST
- His
- Myc
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
IL36B involved in several pathways and played different roles in them. We selected most pathways IL36B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL36B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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IL36B has several biochemical functions, for example, cytokine activity, interleukin-1 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL36B itself. We selected most functions IL36B had, and list some proteins which have the same functions with IL36B. You can find most of the proteins on our site.
Function | Related Protein |
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cytokine activity | IL32;CSF1B;Ccl27a;CSF3;BMP7A;INHBA;IL6;FASLG;GM13288 |
interleukin-1 receptor binding | IL36B;Il1f6;IL1A;IL36G;IL1RN;IL1B;IL37;IL1RAP;IL1F10 |
IL36B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL36B here. Most of them are supplied by our site. Hope this information will be useful for your research of IL36B.
Gene Family
Research Area
Related articles
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewWhen conducting experiments with IL36B, it is easy to operate and does not require complex operating steps.
The stability of IL36B has good adaptability under different temperature and pH conditions.
The structure of IL36B was validated with no abnormal protein folding or inactivation.
Q&As (6)
Ask a questionResearch topics related to IL36B include in-depth study of its signal transduction mechanism, evaluation of therapeutic efficacy, and comparison with other therapeutic approaches.
IL36B exerts its therapeutic role by binding to its receptors, activating signaling pathways and regulating inflammatory and immune responses.
The duration of the IL36B's efficacy will vary from individual to individual, and regular treatment is usually required to maintain the effect.
Yes, there are other treatments similar to IL36B, such as antibody drugs and small molecule compounds.
The dosage and frequency of use are determined according to the specific circumstances of the patient and the results of the clinical trial, and are usually adjusted on an individual basis based on the clinical trial.
The development process of IL36B includes basic research, drug screening, clinical trials and other stages, and has been developed after long-term efforts
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