IL36B

  • Official Full Name

    interleukin 36, beta

  • Overview

    The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

  • Synonyms

    2310043N20Rik;Family of interleukin 1 eta;FIL1;FIL1 (ETA);FIL1 eta;FIL1H;FILI-(ETA);IL 1F8;IL 1F8 (FIL1 eta;IL 1H2;IL-1 eta;IL-1F8;IL-1H2;IL1 ETA;IL1F8;IL1F8 (Canonical product IL 1F8a);IL1F8_HUMAN;IL1H2;IL36B;Interleukin 1 family, member 8;Interleukin 1 family, member 8 (eta);Interleukin 1 homolog 2;Interleukin 1 Superfamily e;Interleukin 36 beta;Interleukin-1 eta;Interleukin-1 family member 8;Interleukin-1 homolog 2;MGC126880;MGC126882;OTTMUSP00000012797;RP23-176J12.1;IL1-ETA;FIL1-(ETA)

Recombinant Proteins

  • Human
  • Mouse
  • E.coli
  • HEK293
  • Human Cells
  • GST
  • Non
  • His
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
IL1F8-14172H Recombinant Human IL1F8, GST-tagged E.coli Human GST 1-157a.a.
IL36B-140H Active Recombinant Human IL36B protein E.coli Human Non
IL36B-852H Active Recombinant Human IL36B E.coli Human Non Arg5-Glu157
Il1f8-646M Recombinant Mouse Il1f8 protein E.coli Mouse Non 153
Il1f8-647M Recombinant Mouse Il1f8 protein E.coli Mouse Non 183
Il1f8-745M Recombinant Mouse Il1f8 protein E.coli Mouse Non Met1-Lys183
IL36B-508H Recombinant Human IL36B protein E.coli Human Non 157
IL36B-509H Recombinant Human IL36B protein E.coli Human Non 153
IL36B-7518H Recombinant Human IL36B protein, His-tagged E.coli Human His Lys5-Glu157
IL36B-752H Recombinant Human IL36B protein(Met1-Glu157) E.coli Human Non Met1-Glu157
IL36B-5236HCL Recombinant Human IL1F8 293 Cell Lysate HEK293 Human Non
IL36B-123H Active Recombinant Human IL36B Protein (Arg5-Glu157), C-His tagged, Animal-free, Carrier-free E.coli Human His Arg5-Glu157
IL36B-151H Recombinant Human IL36B Protein, His-tagged Human Cells Human His
IL36B-197H Recombinant Active Human IL36B Protein, His-tagged(C-ter) E.coli Human His
Il36b-3507M Recombinant Mouse Il36b Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
IL36B-3513H Recombinant Human IL36B Protein (Arg5-Met164), N-His tagged E.coli Human His Arg5-Met164
IL36B-7519H Recombinant Human IL36B protein, His-tagged E.coli Human His 1-157 aa

    Involved Pathway

    IL36B involved in several pathways and played different roles in them. We selected most pathways IL36B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL36B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    IL36B has several biochemical functions, for example, cytokine activity,interleukin-1 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL36B itself. We selected most functions IL36B had, and list some proteins which have the same functions with IL36B. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity IL37,BMP2,GPI1,GDF15,IL32,BMP7B,Ccl9,GPR19,LTA,FGF2
    interleukin-1 receptor binding TLR5,IRAK1,IL1A,TRIP6,IL36G,IL1RAP,IL36RN,IRAK4,IL1RN,IL1F10

    Interacting Protein

    IL36B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL36B here. Most of them are supplied by our site. Hope this information will be useful for your research of IL36B.

    Resources

    Gene Families

    What is the interleukin (IL) factors and IL gene family

    Research Area

    IL-1 Family Ligands

    References

    • Hu, ZL; Chen, ZY; et al. Expression, purification of IL-38 in Escherichia coli and production of polyclonal antibodies. PROTEIN EXPRESSION AND PURIFICATION 107:76-82(2015).
    • Chen, DY; Chen, YM; et al. Th17-Related Cytokines in Systemic Lupus Erythematosus Patients with Dilated Cardiomyopathies: A Possible Linkage to Parvovirus B19 Infection. PLOS ONE 9:-(2014).

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