Active Recombinant Human IL36B Protein (Arg5-Glu157), C-His tagged, Animal-free, Carrier-free
Cat.No. : | IL36B-123H |
Product Overview : | Recombinant Human IL36B Protein (Arg5-Glu157) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-36 beta (IL-36β) is an 18 kDa cytokine with 154 amino acid residues. IL-36β, the ligand of IL-36R, is expressed in keratinocytes and plays a significant role in inflammatory responses. IL-36β regulates biological functions like the differentiation of T cells. Moreover, IL-36β recruits neutrophils via inducing the expression of cytokines and chemokines, such as IL-17C, granulocyte colony-stimulating factor (G-CSF), IL-8, CXCL-1, and tumor necrosis factor (TNF). |
Source : | E. coli |
Species : | Human |
Tag : | C-His |
Form : | Lyophilized |
Bio-activity : | Measure by its ability to induce IL-8 secretion in human PBMCs. The ED50 for this effect is < 0.2 ng/mL. |
Molecular Mass : | The protein has a calculated MW of 18.17 kDa. The protein migrates as 18 kDa under reducing condition (SDS-PAGE analysis). |
Protein Length : | Arg5-Glu157 |
Endotoxin : | < 0.1 EU/μg of the protein by the LAL method. |
Purity : | >98% as determined by SDS-PAGE analysis. |
Storage : | This product is stable after storage at: -20 centigrade for 12 months in lyophilized state from date of receipt. -20 or -80 centigrade for 1 month under sterile conditions after reconstitution. Avoid repeated freeze/thaw cycles. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Shipping : | The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage. |
Gene Name : | IL36B interleukin 36, beta [ Homo sapiens (human) ] |
Official Symbol : | IL36B |
Synonyms : | IL36B; interleukin 36, beta; IL1F8, interleukin 1 family, member 8 (eta); interleukin-36 beta; FIL1; FILI (ETA); IL 1F8; IL 1H2; IL1 ETA; IL1H2; MGC126880; MGC126882; FIL1 eta; IL-1 eta; IL-1F8 (FIL1-eta); interleukin-1 eta; interleukin 1, eta; interleukin-1 homolog 2; Interleukin-1 Superfamily e; family of interleukin 1-eta; interleukin-1 family member 8; IL1F8 (Canonical product IL-1F8a); interleukin 1 family, member 8 (eta); FIL1H; IL1F8; IL-1F8; IL-1H2; IL1-ETA; FIL1-(ETA); FILI-(ETA); |
Gene ID : | 27177 |
mRNA Refseq : | NM_173178 |
Protein Refseq : | NP_775270 |
MIM : | 605508 |
UniProt ID : | Q9NZH7 |
Products Types
◆ Recombinant Protein | ||
Il36b-3507M | Recombinant Mouse Il36b Protein, Myc/DDK-tagged | +Inquiry |
IL36B-197H | Recombinant Active Human IL36B Protein, His-tagged(C-ter) | +Inquiry |
IL36B-752H | Recombinant Human IL36B protein(Met1-Glu157) | +Inquiry |
Il1f8-647M | Recombinant Mouse Il1f8 protein | +Inquiry |
IL36B-140H | Active Recombinant Human IL36B protein | +Inquiry |
◆ Lysates | ||
IL36B-5236HCL | Recombinant Human IL1F8 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket