Ins2

  • Official Full Name

    insulin 2

  • Synonyms

    INS2;insulin 2;insulin-2

Recombinant Proteins

  • Rat
  • Mouse
  • Mammalian Cells
  • Yeast
  • HEK293
  • E.coli
  • His
  • Avi
  • Fc
  • DDK
  • Myc

    Involved Pathway

    Ins2 involved in several pathways and played different roles in them. We selected most pathways Ins2 participated on our site, such as Ras signaling pathway,Rap signaling pathway,cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ins2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    mTOR signaling pathway EIF4E2RS1,EIF4E2,RRAGD,RB1CC1,RPS6,RPS6KB1B,TNF,PRKCA,CAB39L1,RPS6KA1
    Insulin signaling pathway CALM,INS,SOCS4,PRKAB1,PIK3CD,FOXO1A,FLOT1A,ACACB,PTPRFB,INSB
    FoxO signaling pathway INSRA,IKBKB,MAPK12A,ATM,ARAF,RAF1A,KLF2B,PDPK1,IGF1,PRKAG2A
    Aldosterone-regulated sodium reabsorption PIK3CG,PRKCG,MAPK3,KCNJ1,SCNN1G,ATP1A2,ATP1B3,PDPK1,SLC9A3R2,ATP1B2
    AMPK signaling pathway PPP2R5D,CCNA1,CPT1C,MTOR,PPP2R5B,MAP3K7,INSR,ADIPOR1,CAB39,PRKAB2
    Type I diabetes mellitus HLA-DQA1,IL1A,HLA-DOB,HLA-DOA,FASLG,Fasl,H2-AA,HLA-F,HLA-C,HLA-DMA
    Prolactin signaling pathway MAPK9,INS1,STAT5B,CSN2,HRAS,MAP2K1,SOCS5,PIK3R1,FOXO3,MAPK8
    Non-alcoholic fatty liver disease (NAFLD) NDUFA9,TNF,NDUFV1,COX4I2,MAP3K11,UQCRC1,NDUFA13,PKLR,SDHA,COX7A2L
    Regulation of Actin Cytoskeleton ITGA7,PXN,DIAP1,RAC2,INSB,PPP1CBL,FGF8,MAPK6,ITGB1A,ACTB2

    Protein Function

    Ins2 has several biochemical functions, for example, hormone activity,identical protein binding,insulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ins2 itself. We selected most functions Ins2 had, and list some proteins which have the same functions with Ins2. You can find most of the proteins on our site.

    Function Related Protein
    insulin receptor binding DOK5,PDPK1,PIK3R1,IRS4,INS1,DOK2,IGF1,DOK6,PTPN1,IRS1
    insulin-like growth factor receptor binding SOCS1,YWHAG,INS,INSR,IGF2B,REN,IRS1,PIK3R1,IGF2A,ARRB1
    protein complex binding SKIL,SLC25A3,NR0B2,NCKAP1,AP2A2,MYSM1,KAT6B,FBN1,CAV3,LCA5
    hormone activity STC1L,TG,AVP,GAST,C1QTNF9,INHBC,FSD1,CCL25,CALCA,AGT
    protease binding OS9,DVL3,TIMP4,ITGB1,PANX1,LDLR,CCBE1,FLOT1,F3,CHL1
    identical protein binding PVRL2,ATL2,CLDN4,DNM1,TGFB3,FBLN1,PTEN,KRTAP10-5,TNF,SMURF2

    Interacting Protein

    Ins2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ins2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ins2.

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