IQGAP3
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Official Full Name
IQ motif containing GTPase activating protein 3 -
Synonyms
IQGAP3;IQ motif containing GTPase activating protein 3;ras GTPase-activating-like protein IQGAP3;IQGA3_HUMAN;IQGAP 3;MGC10170;MGC10831;MGC1947;OTTHUMP00000031854;OTTHUMP00000031855;Ras GTPase activating like protein IQGAP3
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| IQGAP3-2562H | Recombinant Human IQGAP3 protein, His-tagged | E.coli | Human | His | 530-880 aa | |
| IQGAP3-869HCL | Recombinant Human IQGAP3 cell lysate | Human | Non |
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| IQGAP3-5060H | Recombinant Human IQGAP3 Protein, GST-tagged | Wheat Germ | Human | GST |
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Involved Pathway
IQGAP3 involved in several pathways and played different roles in them. We selected most pathways IQGAP3 participated on our site, such as CDC42 signaling events,RAC1 signaling pathway,RHO GTPase Effectors, which may be useful for your reference. Also, other proteins which involved in the same pathway with IQGAP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of Actin Cytoskeleton | SSH2,CHRM5B,FGF19,GIT1,EGFRA,ACTG1,ARHGEF4,APC,ARPC5LA,ITGB1B.2 |
| Signaling by Rho GTPases | TAGAPB,FGD2,GDI1,RHOT1B,TAX1BP3,NOXO1A,ARHGAP20,RHPN2,ARHGAP12,PLEKHG2 |
| RHO GTPase Effectors | ROPN1,ABI1,RHOC,RTKN,NOXA1,NOXO1,RCC2,WIPF3,ABI2,NSL1 |
| CDC42 signaling events | ARPC4,BAIAP2,TNK2,ARPC1B,ARPC2,CFL1,CDC42BPA,ARPC3,ARPC5,ACTR3 |
| Signal Transduction | RLN2,KLHL12,PDK4,AMOTL2A,TRH,HCRT,TAGAPB,RLBP1A,DNER,AKR1C6 |
| RAC1 signaling pathway | ABI1,NOXO1,NOXA1,RACGAP1,NCKAP1,ABI2,BAIAP2 |
Protein Function
IQGAP3 has several biochemical functions, for example, GTPase activator activity,Rho GTPase binding,calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IQGAP3 itself. We selected most functions IQGAP3 had, and list some proteins which have the same functions with IQGAP3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| Rho GTPase binding | DOCK10,LRRK2,ARHGEF2,ARHGEF16,DIAPH3,DOCK11,DIAP1,DAAM1B,CDC42BPB,AKAP13 |
| calmodulin binding | EDF1,ADD3,MYO1E,TRPV4,MYH10,SMTNL1,MKNK2A,CAMSAP1,RYR2,SPTAN1 |
| GTPase activator activity | CHN1,NF1,SH3BGRL3,DOCK2,ARHGAP8,RIC8A,TBC1D20,RGS7,SIPA1L1,FAM13B1 |
Interacting Protein
IQGAP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IQGAP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of IQGAP3.
Ndc80;pi3p;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate;PTBP3;MYC;CDC42;Smn1;IQCB1;LRRK2;Kctd5
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