Itga10
-
Official Full Name
integrin, alpha 10 -
Synonyms
PRO827
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ITGA10-5136HCL | Recombinant Human ITGA10 293 Cell Lysate | HEK293 | Human | Non |
|
|
| ITGA10-249H | Recombinant Human ITGA10 Protein, His-tagged | E.coli | Human | His | Ser901~Glu1108 |
|
| Itga10-250M | Recombinant Mouse Itga10 Protein, His-tagged | E.coli | Mouse | His | Glu919~Phe1088 |
|
| ITGA10-3210H | Recombinant Human ITGA10 Protein (Asp167-Leu350), N-His tagged | E.coli | Human | His | Asp167-Leu350 |
|
Involved Pathway
Itga10 involved in several pathways and played different roles in them. We selected most pathways Itga10 participated on our site, such as PIK-Akt signaling pathway,Focal adhesion,ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with Itga10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ECM-receptor interaction | SV2B,ITGA1,SV2C,COL4A3,SDC4,SPP1,TNW,COL6A3,ITGB3,ITGB1B.2 |
| PIK-Akt signaling pathway | PPP2CA,MLST8,TCL1B1,PDGFB,INSR,THBS2,ITGB1,GNG12,COL6A5,FGF2 |
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ACTN1,ITGA9,ITGA7,JUP,CACNA2D2,ACTN2,SLC8A1,DSC2,ACTG1,ITGA1 |
| Focal adhesion | COL27A1,MAPK8,ITGB6,PIP5K1C,IGF1RB,ACTB,GSK3AA,PDGFB,PIK3R3,ACTN2B |
| Regulation of Actin Cytoskeleton | MYL10,SSH2,PPP1CC,ITGAX,SSH3,PDGFRB,WAS,FGF4,PIP4K2B,NRAS |
| Dilated cardiomyopathy | CACNG6,CACNG3,DMD,CACNG4,ITGB7,TNNI3,ACTB,ITGA9,CACNG7,TTN |
| Hypertrophic cardiomyopathy (HCM) | TPM3,CACNA2D3,Itga10&Itgb1,CACNG6,CACNB4,SGCG,TGFB2,PRKAG2,ITGA8,SGCB |
Protein Function
Itga10 has several biochemical functions, for example, collagen binding,collagen binding involved in cell-matrix adhesion,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Itga10 itself. We selected most functions Itga10 had, and list some proteins which have the same functions with Itga10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| collagen binding | DDR2,ITGA2,CCBE1,SERPINH2,LUM,SPARC,USH2A,PDGFA,MMP9,PCOLCE |
| collagen binding involved in cell-matrix adhesion | Itga10&Itgb1,ITGA2,ITGB1,ITGA1 |
| metal ion binding | THAP7,MGRN1A,SUV39H1A,CYP46A1.1,ZNF37A,NT5C2L1,TRIM36,ZNF223,CYB561A3A,PRKCZ |
Interacting Protein
Itga10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Itga10 here. Most of them are supplied by our site. Hope this information will be useful for your research of Itga10.
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References
- Mochmann, LH; Neumann, M; et al. ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells. ONCOTARGET 5:351-362(2014).
- Kyostila, K; Lappalainen, AK; et al. Canine Chondrodysplasia Caused by a Truncating Mutation in Collagen-Binding Integrin Alpha Subunit 10. PLOS ONE 8:-(2013).
