Itga10

  • Official Full Name

    integrin, alpha 10
  • Synonyms

    PRO827
Cat.# Product name Source (Host) Species Tag Protein Length Price
ITGA10-5136HCL Recombinant Human ITGA10 293 Cell Lysate HEK293 Human Non
ITGA10-249H Recombinant Human ITGA10 Protein, His-tagged E.coli Human His Ser901~Glu1108
Itga10-250M Recombinant Mouse Itga10 Protein, His-tagged E.coli Mouse His Glu919~Phe1088
ITGA10-3210H Recombinant Human ITGA10 Protein (Asp167-Leu350), N-His tagged E.coli Human His Asp167-Leu350

    Involved Pathway

    Itga10 involved in several pathways and played different roles in them. We selected most pathways Itga10 participated on our site, such as PIK-Akt signaling pathway,Focal adhesion,ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with Itga10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Arrhythmogenic right ventricular cardiomyopathy (ARVC) Itga10&Itgb1,LAMA2,ACTN2,CTNNA2,ACTG1,CACNB4,ATP2A2,DAG1,LEF1,ITGA6
    Hypertrophic cardiomyopathy (HCM) TPM4,IGF1,ITGB4,SGCA,IL6,PRKAG3,CACNA2D4,ITGB6,TNF,ITGB8
    ECM-receptor interaction TNC,LAMA1,THBS3,VTNB,COL1A1,SDC4,COL5A1,THBS2,COL4A3,DAG1
    Focal adhesion PARVA,KDR,VEGFAA,PRKCBB,ITGA6,RHOA,Reln,PDPK1,COL27A1A,RAC3
    Dilated cardiomyopathy ITGA8,CACNB2,CACNB1,ADRB1,TNNC1,TTN,ACTC1,ITGA6,DES,PRKACB
    Regulation of Actin Cytoskeleton SCINLA,INS,FGF12A,ACTB1,GSNB,F2,RAF1,PIP5K1AB,MYL9A,VAV3
    PIK-Akt signaling pathway LAMA5,TNN,LPAR3,FGFR4,GNG13,PPP2R2C,EPOR,FGF17,GYS2,FGF19

    Protein Function

    Itga10 has several biochemical functions, for example, collagen binding,collagen binding involved in cell-matrix adhesion,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Itga10 itself. We selected most functions Itga10 had, and list some proteins which have the same functions with Itga10. You can find most of the proteins on our site.

    Function Related Protein
    collagen binding involved in cell-matrix adhesion ITGB1,ITGA2,ITGA1,Itga10&Itgb1
    metal ion binding ZNF670,CARNS1,MFNG,GNAO1,ZNHIT3,FGD6,ZNF143,ENTPD7,GART,LFNG
    collagen binding MRC2,VWF,LRRC15,PAK1,PCOLCE,CHADL,DCN,SERPINH1,ANTXR1,DDR1

    Interacting Protein

    Itga10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Itga10 here. Most of them are supplied by our site. Hope this information will be useful for your research of Itga10.

    Fabp3

    Resources

    Research Area

    References

    • Mochmann, LH; Neumann, M; et al. ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells. ONCOTARGET 5:351-362(2014).
    • Kyostila, K; Lappalainen, AK; et al. Canine Chondrodysplasia Caused by a Truncating Mutation in Collagen-Binding Integrin Alpha Subunit 10. PLOS ONE 8:-(2013).

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