JHDM1D
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Official Full Name
jumonji C domain containing histone demethylase 1 homolog D -
Synonyms
JHDM1D;jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae);lysine-specific demethylase 7;KIAA1718;histone lysine demethylase JHDM1D;jmjC domain-containing histone demethylation protein 1D;jumonji C domain-containing histone d
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| JHDM1D-46H | Recombinant Human JHDM1D, GST-tagged | E.coli | Human | Non | 1-488 a.a. |
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| JHDM1D-47H | Recombinant Human JHDM1D | E.coli | Human | Non | 92-488 a.a. |
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| JHDM1D-8419M | Recombinant Mouse JHDM1D Protein | Mammalian Cells | Mouse | His |
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| JHDM1D-4675M | Recombinant Mouse JHDM1D Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| JHDM1D-4675M-B | Recombinant Mouse JHDM1D Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
JHDM1D involved in several pathways and played different roles in them. We selected most pathways JHDM1D participated on our site, such as Chromatin modifying enzymes,Chromatin organization,HDMs demethylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with JHDM1D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chromatin modifying enzymes | GATAD2AB,SMARCE1,SETD3,KDM1A,TADA2B,BRPF3,BRPF1,PADI4,KDM1B,EED |
| HDMs demethylate histones | KDM5B,KDM5BB,KDM6AL,PHF8,KDM5BA,KDM2AA,KDM5D,KDM3A,KDM7AB,KDM5C |
| Chromatin organization | MSL2,ARID5B,KAT8,GATAD2AB,MTA2,DNMT3A,PBRM1L,KDM3B,RBBP5,CCDC101 |
Protein Function
JHDM1D has several biochemical functions, for example, histone demethylase activity (H3-K27 specific),histone demethylase activity (H3-K36 specific),histone demethylase activity (H3-K9 specific). Some of the functions are cooperated with other proteins, some of the functions could acted by JHDM1D itself. We selected most functions JHDM1D had, and list some proteins which have the same functions with JHDM1D. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| histone demethylase activity (H3-K36 specific) | KDM8,PHF8,KDM4A,KDM2A,KDM2B,JMJD5,C14orf169 |
| histone demethylase activity (H3-K9 specific) | KDM1A,KDM4C,PHF8,KDM7AB,PHF2,KDM4D |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | C14orf169,ALKBH5,EGLN2,ALKBH8,KDM5D,KDM5B,KDM5BA,ALKBH4,HIF1AN,PHF8 |
| histone demethylase activity (H4-K20 specific) | HIST1H4H,HIST1H4J,HIST1H4F,HIST1H4L,HIST1H4I,HIST1H4K,HIST1H4B,PHF8,HIST1H4C,HIST1H4A |
| histone demethylase activity (H3-K27 specific) | KDM6BB,PHF8,KDM7AB,KDM6B,KDM6A |
| iron ion binding | CYP2K6,SC5DL,CYP2F2,P4HA1,CYP2AA1,PLOD1A,PHF2,CYP4B1,HBE1,CYP4F14 |
| zinc ion binding | DTX2,BTR18,NSD1,S100B,BAZ2A,CPA2,CNBP,TAB2,APOBEC3C,TRAF2 |
| methylated histone binding | CHD1,MSH6,ING1,GLYR1,CBX7,SUZ12,CHD8,ING3,SPIN1,ATRX |
Interacting Protein
JHDM1D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with JHDM1D here. Most of them are supplied by our site. Hope this information will be useful for your research of JHDM1D.
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References
- Koelsch, KA; Webb, R; et al. Functional characterization of the MECP2/IRAK1 lupus risk haplotype in human T cells and a human MECP2 transgenic mouse. JOURNAL OF AUTOIMMUNITY 41:168-174(2013).
