kif17

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kif17

Official Full Name kinesin family member 17
Background Kinesin-like protein KIF17 is a protein that in humans is encoded by the KIF17 gene.KIF17 and its close relative, C. elegans OSM-3,are members of the kinesin-2 family of plus-end directed microtubule-based motor proteins.In contrast to heterotrimeric kinesin-2 motors,however, KIF17 and OSM-3 form distinct homodimeric complexes.Homodimeric kinesin-2 has been implicated in the transport of NMDA receptors along dendrites for delivery to the dendritic membrane,whereas both heterotrimeric and homodimeric kinesin-2 motors function cooperatively in anterograde intraflagellar transport (IFT) and cilium biogenesis.
Synonyms KIF17; kinesin family member 17; kinesin-like protein KIF17; KIAA1405; KIF3 related motor protein; KIF3X; KIF17 variant protein; KIF17B; kinesin like protein KIF17; KIF3-related motor protein
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • Tag :
    • GST
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human KIF17-360H Recombinant Human KIF17, GST-tagged E.coli GST
    Human KIF17-4953HCL Recombinant Human KIF17 293 Cell Lysate HEK293 N/A

    kif17 involved in several pathways and played different roles in them. We selected most pathways kif17 participated on our site, such as Assembly of the primary cilium, Intraflagellar transport, Organelle biogenesis and maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with kif17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Assembly of the primary cilium CNGA2; BBS5; CEP290; CEP89; WDR34; TCP1; DYNLL2B; EXOC3; TNPO1; WDR19
    Intraflagellar transport DYNLL2A; DYNLRB2; IFT46; C11orf60; IFT43; DYF-1; IFT20; KIF17; TCTEX1D2; IFT80
    Organelle biogenesis and maintenance ARF4A; BBS12; IFT80; MRRF; MRPS27; FBF1; IFT122; LZTFL1; BBS1; MRPL51

    kif17 has several biochemical functions, for example, ATP binding, ATP-dependent microtubule motor activity, plus-end-directed, microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by kif17 itself. We selected most functions kif17 had, and list some proteins which have the same functions with kif17. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding CDK7; MAGI3; RPS6KB2; OAS1B; ABCA3; PTK2AB; NLRP11; CDC42BPA; CDK5; MARS2
    ATP-dependent microtubule motor activity, plus-end-directed KIF1C; KIF1B; KIF16B; KIF5AA; KIF17; KIF5C; KIF19; KIF5A; KIF18A; KIF20B
    microtubule binding GABARAP; RAE1; EZR; FGF13; FES; CCDC87; GABARAPA; KIF13B; KIF5AA; CAMSAP1B

    kif17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with kif17 here. Most of them are supplied by our site. Hope this information will be useful for your research of kif17.

    q5nig6_fratt; GFI1B; q9wmx2-pro_0000037548

    Seog, DH; Han, J; et al. Sorting nexin 17 interacts directly with kinesin superfamily KIF1B beta protein. KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY 12:199-204(2008).

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