KIF18A

  • Official Full Name

    kinesin family member 18A

  • Overview

    KIF18A is a member of the kinesin superfamily of microtubule-associated molecular motors (see MIM 148760) that use;hydrolysis of ATP to produce force and movement along microtubules (Luboshits and Benayahu, 2005 (PubMed;15878648)).

  • Synonyms

    KIF18A;kinesin family member 18A;kinesin-like protein KIF18A;DKFZP434G2226;MS-KIF18A

Recombinant Proteins

  • Human
  • Zebrafish
  • Chicken
  • E.coli
  • Bacteria
  • Mammalian Cells
  • HEK293
  • GST
  • His
  • Non
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
KIF18A-361H Recombinant Human KIF18A, GST-tagged E.coli Human GST 1-279aa
KIF18A-263H Recombinant Human KIF18A Protein, His-tagged E.coli Human His Met1~Lys453
KIF18A-12H Recombinant Human KIF18A Protein, His-tagged Bacteria Human His 1-374 aa
KIF18A-1049H Recombinant Human KIF18A Mammalian Cells Human His
KIF18A-10579Z Recombinant Zebrafish KIF18A Mammalian Cells Zebrafish His
KIF18A-4299C Recombinant Chicken KIF18A Mammalian Cells Chicken His
KIF18A-4952HCL Recombinant Human KIF18A 293 Cell Lysate HEK293 Human Non
KIF18A-3213H Recombinant Human KIF18A Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
KIF18A-3213H-B Recombinant Human KIF18A Protein Pre-coupled Magnetic Beads HEK293 Human

    Involved Pathway

    KIF18A involved in several pathways and played different roles in them. We selected most pathways KIF18A participated on our site, such as Adaptive Immune System,Cell Cycle,Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF18A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System DTX3L,BLMH,RAPGEF3,LILRA3,DCTN2,SPSB4,PJA1,TRIM11,DYNC1LI2,ARIH2
    M Phase B9D2,CENPQ,RCC2,CENPN,CDCA8,CTDNEP1B,VRK2,ENSAB,SPC24,CENPE
    Immune System CFHL4,ASB14,FCN1,AP1B1,SEC23A,ACTR1B,HERC5,SPSB4,ERAP2,ASB10
    Hemostasis BA2,KIF3B,HRG,DOCK8,CFHL4,KCNMA1,ATP2B3A,SIRPA,AASS,KIF3C
    Factors involved in megakaryocyte development and platelet production MFN1,KIF22,OSTN,MAFG,KIF3B,HBG1,KIF4,D-AKAP2,ZFPM2A,MAFGA
    Cell Cycle, Mitotic BLZF1,NCAPD3,ZWILCH,DBF4,PHF8,CTDNEP1B,LIN37,CLASP1,CLASP1A,ZWINT
    Cell cycle DPF1,MASTL,CCNB2,NPM1,CHEK2,POT1A,MYCB,CEP72,KIF2C,RAD21
    Kinesins KIFAP3,KIF22,KIF3B,KIF4,KIF26A,CENPE,KIF2C,KIF15,KIF2A,KIF5A

    Protein Function

    KIF18A has several biochemical functions, for example, ATP binding,ATP-dependent microtubule motor activity, plus-end-directed,actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF18A itself. We selected most functions KIF18A had, and list some proteins which have the same functions with KIF18A. You can find most of the proteins on our site.

    Function Related Protein
    microtubule binding PAFAH1B1B,POLB,CDK5RAP2,MTAP1A,WDR43,SERPINB1A,SNCA,DNM2,ARHGEF2,CLIP3
    actin binding ITGB1,ADD1,MYH8,DIAP3,ENC1,DBNL,EVLB,MYOT,KLHL20,CAP1
    ubiquitin binding MARK4,SQSTM1,NPLOC4,BCL10,UCHL1,SMAD3,TRIM32,FAF1,USP16,SHRPRBCK1R
    ATP binding HIPK3B,ATP13A1,CHD4A,PPIP5K2,ZAP70,GLULB,NOD1,HK3,INSR,EIF2AK1
    ATP-dependent microtubule motor activity, plus-end-directed KIF14,KIF17,KIF5AA,KIF1C,KIF1B,KIF3B,KIF3A,KIF19,KIF5B,KIF11
    microtubule plus-end binding CLIP1,CLASP1A,DST,APC,CLASP1,KIF2C,MAPRE1,CLIP2,STIM1
    protein binding SOAT1,CD79B,TINAGL1,FIBCD1,RAB1B,ZMYND10,NID2,ITGAV,UBE2D4,HBP1

    Interacting Protein

    KIF18A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF18A here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF18A.

    ANAPC4;NFKBIB;PPP1CA;NCOR1;TCF3;PPP1CC;TTC3;CSE1L;Ppp1cb;FOXM1;PSMD5;C18orf21;GKAP1;Kif18b;SAMD1;Kif1bp;CASC5;Cdc16;EME1

    Resources

    Gene Families

    References

    • Zusev, M; Benayahu, D; et al. New Insights on Cellular Distribution, Microtubule Interactions and Post-Translational Modifications of MS-KIF18A. JOURNAL OF CELLULAR PHYSIOLOGY 217:618-625(2008).
    • Luboshits, G; Benayahu, D; et al. MS-KIF18A, a kinesin is associated with estrogen receptor. JOURNAL OF CELLULAR BIOCHEMISTRY 100:693-702(2007).

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