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KIF18A

Official Full Name

kinesin family member 18A
Overview

KIF18A is a member of the kinesin superfamily of microtubule-associated molecular motors (see MIM 148760) that use;hydrolysis of ATP to produce force and movement along microtubules (Luboshits and Benayahu, 2005 (PubMed;15878648)).
Synonyms

KIF18A; kinesin family member 18A; kinesin-like protein KIF18A; DKFZP434G2226; MS-KIF18A;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Zebrafish

Source

Bacterial expression system
E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	KIF18A-12H	Recombinant Human KIF18A Protein, His-tagged	Bacterial expression system	His	1-374 aa	Inquiry
Human	KIF18A-361H	Recombinant Human KIF18A, GST-tagged	E.coli	GST	1-279aa	$319 / 25ug
Human	KIF18A-1049H	Recombinant Human KIF18A	Mammalian Cell	His		Inquiry
Human	KIF18A-4952HCL	Recombinant Human KIF18A 293 Cell Lysate	HEK293	N/A		Inquiry
Human	KIF18A-3213H	Recombinant Human KIF18A Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	KIF18A-263H	Recombinant Human KIF18A Protein, His-tagged	E.coli	His	Met1~Lys453	$298 / 10ug
Human	KIF18A-3213H-B	Recombinant Human KIF18A Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	KIF18A-10579Z	Recombinant Zebrafish KIF18A	Mammalian Cell	His		Inquiry
Chicken	KIF18A-4299C	Recombinant Chicken KIF18A	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
KIF18A Related Articles
KIF18A Related Gene Family

KIF18A involved in several pathways and played different roles in them. We selected most pathways KIF18A participated on our site, such as Adaptive Immune System, Cell Cycle, Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF18A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Adaptive Immune System	STUB1;AP2B1;CD300LG;CTSK;SPSB2;CD300LD;AP2S1;HCST;SEC23A
Cell Cycle	TSGA14;MCM6;SMC4;HDAC6;MPEG1;ANAPC5;GADD45B;CCNA2;GORASP1
Cell Cycle, Mitotic	ARPP19B;CNEP1R1;CDKN2C;TCTN2;CKAP5;NIPBL;CENPK;FGFR1OP;AHCTF1
Factors involved in megakaryocyte development and platelet production	VPS45;KIF4;HBBE1.1;HBD;KIF15;ITPK1;PHF21A;KLC3;NFE2
Hemostasis	GRB14;ESAMA;AMICA1;ANGPT2A;F3A;CEACAM1;CFHL2;KIF2B;VPS45
Immune System	SIGLEC12;ASB10;POLR3H;ASB18;TRIM41;LGALS9;TRIM5;LILRB5;UBE2U
Kinesins	KIF2B;KIFAP3;KIF22;KIF26A;KIF3B;KIF2C;KIF2A;RACGAP1;KIF4A
M Phase	CNEP1R1;CENPK;RANGAP1B;NDEL1A;USO1;SMC4;LEMD3;CENPN;KIF2A

KIF18A has several biochemical functions, for example, ATP binding, ATP-dependent microtubule motor activity, plus-end-directed, actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF18A itself. We selected most functions KIF18A had, and list some proteins which have the same functions with KIF18A. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	MTHFD1L;PSMC2;DNAH5;CCT3;TTBK2;DAPK2A;EIF4A1A;RET;NMNAT3
ATP-dependent microtubule motor activity, plus-end-directed	KIF3A;KIF5AA;KIF5A;KIF11;KIF14;KIF5C;KIF18B;KIF18A;KIF1B
actin binding	SMYHC1;TRPV4;FHOD3;WASB;PTK2;MYHC4;SHANK3;MKL1;DMTN
microtubule binding	KIF3CB;NDEL1A;WDR81;CAMSAP1A;RGS14;KIFC3;FAM83D;CETN2;RCC2
microtubule plus-end binding	CLASP1;KIF18A;CLASP1A;CLIP1;DST;KIF2C;MAPRE1;APC;CLIP2
protein binding	FGF7;CDC27;FBXO6;CENPA;EGFR;NFATC1;FAP;NRBP1;E2F2
tubulin-dependent ATPase activity
ubiquitin binding	TOP2A;OTUB2;HSPB1;KCNS1;FAN1;UCHL3;RNF168;SMAD3;MARK4

KIF18A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF18A here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF18A.

ANAPC4; NFKBIB; PPP1CA; NCOR1; TCF3; PPP1CC; TTC3; CSE1L; Ppp1cb; FOXM1; PSMD5; C18orf21; GKAP1; Kif18b; SAMD1; Kif1bp; CASC5; Cdc16; EME1

Zusev, M; Benayahu, D; et al. New Insights on Cellular Distribution, Microtubule Interactions and Post-Translational Modifications of MS-KIF18A. JOURNAL OF CELLULAR PHYSIOLOGY 217:618-625(2008).

Luboshits, G; Benayahu, D; et al. MS-KIF18A, a kinesin is associated with estrogen receptor. JOURNAL OF CELLULAR BIOCHEMISTRY 100:693-702(2007).