KIF2C
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Official Full Name
kinesin family member 2C -
Overview
The protein encoded by this gene is a member of kinesin-like protein family. Proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation. [provided by RefSeq, Jul 2008] -
Synonyms
KIF2C;kinesin family member 2C;MCAK;CT139;KNSL6;kinesin-like protein KIF2C;kinesin-like 6;kinesin-like protein 6;mitotic centromere-associated kinesin
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KIF2C-372H | Recombinant Human KIF2C, GST-tagged | E.coli | Human | GST | 255-518aa | |
| KIF2C-6456Z | Recombinant Zebrafish KIF2C | Mammalian Cells | Zebrafish | His |
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| KIF2C-4946HCL | Recombinant Human KIF2C 293 Cell Lysate | HEK293 | Human | Non |
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| KIF2C-1164H | Recombinant Human KIF2C Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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| Kif2c-3693M | Recombinant Mouse Kif2c Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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Involved Pathway
KIF2C involved in several pathways and played different roles in them. We selected most pathways KIF2C participated on our site, such as Adaptive Immune System,Aurora B signaling,Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF2C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Immune System | FAM49BA,HUWE1,BAIAP2,DCTN3,NPEPPS,POLR3C,CTSD,FBXO17,SIGLEC7,WWP1 |
| Cell Cycle, Mitotic | CENPE,DCTN1,NEK9,TUBGCP4,DPF1,DCTN1A,CDK7,CENPK,LIN37,ENSA |
| Aurora B signaling | SEPT1,INCENP,SMC4,NCAPH,SGOL1,KIF20A,DES,AURKB,NPM1,NSUN2 |
| Adaptive Immune System | ATG7,LILRA2,TRAT1,RNF220,MOV10,CLTA,KLC3,GM11711,WWP1,BTLA |
| Kinesins | KIF3B,KIF22,CENPE,KIF11,RACGAP1,KLC3,KIF18A,KIFC1,KIF5A,KIF2A |
| Factors involved in megakaryocyte development and platelet production | GATA5,DOCK9,H3F3D,MFN2,HBB-Y,DOCK10,HBBE1.1,HBD,MFN1,DOCK1 |
| Hemostasis | F9A,ZFPM1,F11R.2,F13A1B,ITPK1,SLC16A8,HBBE3,SERPINE2,MMRN2A,GATA2A |
| Cell cycle | PLK1,TFDP1,CLSPN,PDS5B,KIF18A,MYC,NEK9,DULLARD,LEMD3,CEP72 |
Protein Function
KIF2C has several biochemical functions, for example, ATP binding,ATPase activity,centromeric DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF2C itself. We selected most functions KIF2C had, and list some proteins which have the same functions with KIF2C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| microtubule motor activity | KIF5B,KIF5C,KIF7,KIFC3,KIF3B,KLC3,KIF14,KLC2,KIF5AA,DNHD1 |
| protein binding | PARP9,SLC30A1,LGALS2,UBE2D4,CDKN1C,TBCEL,TUBB,CATSPERG2,RIPPLY3,BFAR |
| ATP binding | HSPD1,TTLL6,EHD1,TOR1,LARS,RPS6KC1,MKNK1,HIPK4,CDK17,PRKCE |
| microtubule plus-end binding | MAPRE1,DST,CLASP1,STIM1,CLIP1,KIF18A,CLASP1A,APC,CLIP2 |
| ATPase activity | RHOBTB3,NSFB,RNF213,ATAD1B,ABCB6,TOR1B,ABCA5,ABCA4,MLH3,ABCA1B |
| centromeric DNA binding | MSH3,MLH3,ZW10,MSH2,CENPB,CENPC1 |
Interacting Protein
KIF2C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF2C here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF2C.
MAPRE1;MTUS2;VHL;CSNK2B;ZNF566;KIF2A;KIF2A;SRGAP3;WDR62;CENPB;RPL7;VCAM1
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