KIF2C

  • Official Full Name

    kinesin family member 2C

  • Overview

    The protein encoded by this gene is a member of kinesin-like protein family. Proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation. [provided by RefSeq, Jul 2008]

  • Synonyms

    KIF2C;kinesin family member 2C;MCAK;CT139;KNSL6;kinesin-like protein KIF2C;kinesin-like 6;kinesin-like protein 6;mitotic centromere-associated kinesin
Cat.# Product name Source (Host) Species Tag Protein Length Price
KIF2C-372H Recombinant Human KIF2C, GST-tagged E.coli Human GST 255-518aa
KIF2C-6456Z Recombinant Zebrafish KIF2C Mammalian Cells Zebrafish His
KIF2C-4946HCL Recombinant Human KIF2C 293 Cell Lysate HEK293 Human Non
KIF2C-1164H Recombinant Human KIF2C Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
Kif2c-3693M Recombinant Mouse Kif2c Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc

    Involved Pathway

    KIF2C involved in several pathways and played different roles in them. We selected most pathways KIF2C participated on our site, such as Adaptive Immune System,Aurora B signaling,Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF2C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Factors involved in megakaryocyte development and platelet production IRF2,VPS45,SH2B3,DOCK11,CBX5,BA1L,ZFPM1,KIF20A,KIFAP3,MAFGB
    Immune System MYO9B,UNC93B1,S100B,ASB18,UBR1,KIF5B,SIGLEC14,RNF182,STUB1,KIF2B
    Hemostasis RACGAP1,KIF5A,CXADR,F9B,CBX5,HBG1,CD177,HBBE3,KIF5B,DOCK10
    Kinesins KIFAP3,KIF2A,RACGAP1,CENPE,KIF22,KIF15,KIF3B,KIF26A,KIF4,KIF5A
    Aurora B signaling DES,CBX5,NPM1,PEBP1,CDCA8,INCENP,NDC80,AURKB,RACGAP1,KIF20A
    Adaptive Immune System ACTR1A,CTSL1,MGC174152,UBR2,RNF220,LRRC41,SEC23A,NRG4,MGC174155,RNF25
    Cell cycle RAD50,BRCC3,GINS3,TSGA14,CHEK1,ARPP19B,E2F4,CP110,CTDNEP1A,MSH4
    Cell Cycle, Mitotic HAUS2,ACTR1A,ENSA,LIN54,CENPN,CLIP1,PDS5B,CDK11A,SPC25,SPDL1

    Protein Function

    KIF2C has several biochemical functions, for example, ATP binding,ATPase activity,centromeric DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF2C itself. We selected most functions KIF2C had, and list some proteins which have the same functions with KIF2C. You can find most of the proteins on our site.

    Function Related Protein
    protein binding SARM1,PHF21A,APOE,CDC26,ORC6L,EIF4B,PDGFA,ANLN,CA4,C11orf65
    ATPase activity HSP90AA1,KIF12,MYH8,KIFC2,MYO9B,SMARCA5,ABCA5,INO80,TOR1B,DNAH11
    microtubule motor activity KIF5AA,SMC3,KIF13B,DYNC2H1,DYNC1LI2,KIF9,KIF11,KIFC3,KIF4,DNALI1
    centromeric DNA binding ZW10,CENPC1,MSH2,MLH3,CENPB,MSH3
    ATP binding IGF1R,DDX21,DDX19B,OXSR1B,KIFC1,ABCA1B,PIK3CA,HIPK3B,VRK1,DDX10
    microtubule plus-end binding CLIP2,KIF18A,CLASP1A,STIM1,MAPRE1,DST,CLASP1,APC,CLIP1

    Interacting Protein

    KIF2C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF2C here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF2C.

    MAPRE1;MTUS2;VHL;CSNK2B;ZNF566;KIF2A;KIF2A;SRGAP3;WDR62;CENPB;RPL7;VCAM1

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