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Official Full Name kinesin family member 3B
Background The protein encoded by this gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of membranous organelles. This protein and kinesin family member 3A form the kinesin II subfamily of the kinesin superfamily.
Synonyms KIF3B; kinesin family member 3B; kinesin-like protein KIF3B; KIAA0359; HH0048; KIF3B_HUMAN; Kinesin like protein KIF3B; Microtubule plus end directed kinesin motor 3B; Microtubule plus end-directed kinesin motor 3B; Similar to Mouse kinesin KIF3B; OTTHUMP00000030588
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human KIF3B-3962H Recombinant Human KIF3B Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human KIF3B-931HCL Recombinant Human KIF3B cell lysate N/A
    Mouse Kif3b-1268M Recombinant Mouse Kif3b Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rhesus Macaque KIF3B-2406R Recombinant Rhesus monkey KIF3B Protein, His-tagged Mammalian Cell His
    Chicken KIF3B-2058C Recombinant Chicken KIF3B Mammalian Cell His
    Zebrafish KIF3B-5883Z Recombinant Zebrafish KIF3B Mammalian Cell His

    kif3b involved in several pathways and played different roles in them. We selected most pathways kif3b participated on our site, such as Adaptive Immune System, Assembly of the primary cilium, Factors involved in megakaryocyte development and platelet production, which may be useful for your reference. Also, other proteins which involved in the same pathway with kif3b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System ERAP1; ASB7; DCTN3; RNF138; NRG3; ASB10; LRSAM1; UBE2F; KLRG1; FRS2
    Assembly of the primary cilium IFT81; IFT122; C11orf60; IFT172; LZTFL1; KIF3CB; FLR; CEP76; FBF1; NPHP4
    Factors involved in megakaryocyte development and platelet production MFN2; VPS45; MFN1; MYB; KIF22; GATA6; ITPK1; MAFG; RACGAP1; GATA1
    Hemostasis DOCK10; MGC173646; SLC8A2A; SCG3; GATA2; CFD; ITPK1; CD9B; MAFGB; JAM2B
    Immune System LRRC41; TREML1; SAMHD1; CD300LH; NCR3LG1; HERC5; GZMM; PELI1; SLAMF6; Siglece
    Intraflagellar transport KIF3B; WDR19; C11orf60; TTC30A; TCTEX1D2; IFT52; IFT20; IFT122; RABL5; DYNLRB2
    MHC class II antigen presentation IFI30; KIF3B; MGC174857; FAM49BA; AP1S3A; CTS7; RACGAP1; KIFAP3; KIF3C; KIF11

    kif3b has several biochemical functions, for example, ATP binding, ATP-dependent microtubule motor activity, plus-end-directed, Rho GTPase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by kif3b itself. We selected most functions kif3b had, and list some proteins which have the same functions with kif3b. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding ABCC8; KIF3CB; CHUK; ACTA1B; TYRO3; BCS1L; AK1; ACTC1; MYH15; ILF2
    ATP-dependent microtubule motor activity, plus-end-directed KIF1B; KIF20B; KIF3A; KIF16B; KIF5C; KIF5AA; KIF17; KIF5B; KIF3B; KIF18A
    Rho GTPase binding DAPK3; INF2; RHOH; ROCK2B; ANTXR2A; ROCK2; DOCK11; DOCK10; IQGAP3; AKAP13
    microtubule binding MAP6D1; PRC1A; KIF26A; KIF5C; KIFC1; TERF1; SKA1; ARHGEF2; HAUS8; GABARAPA
    microtubule motor activity DNALI1; DYNC1LI1; KLC1A; APPBP2; KLC3; DNAHC8; KIF3CB; KIF23; KIF2B; DNAH11
    protein binding RBFA; MBP; PEX5; LYRM2; G0S2; POLR2C; DPYSL5; RHNO1; ADSS; SLC3A2

    kif3b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with kif3b here. Most of them are supplied by our site. Hope this information will be useful for your research of kif3b.

    KIFAP3; ARHGEF10; LMO2; LMO4; Mphosph9; Hax1; Magoh; Sptlc2; KIF3A; Homer1

    Qiu, DY; Cheng, SM; et al. Localization and loss-of-function implicates ciliary proteins in early, cytoplasmic roles in left-right asymmetry. DEVELOPMENTAL DYNAMICS 234:176-189(2005).
    Baker, SA; Freeman, K; et al. IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia. JOURNAL OF BIOLOGICAL CHEMISTRY 278:34211-34218(2003).

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