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KIF3B

  • Official Full Name

    kinesin family member 3B

  • Overview

    The protein encoded by this gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of membranous organelles. This protein and kinesin family member 3A form the kinesin II subfamily of the kinesin superfamily.
  • Synonyms

    KIF3B; kinesin family member 3B; kinesin-like protein KIF3B; KIAA0359; HH0048; KIF3B_HUMAN; Kinesin like protein KIF3B; Microtubule plus end directed kinesin motor 3B; Microtubule plus end-directed kinesin motor 3B; Similar to Mouse kinesin KIF3B; OTTHUMP00000030588;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KIF3B-931HCL Recombinant Human KIF3B cell lysate N/A
Human KIF3B-3962H Recombinant Human KIF3B Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Kif3b-1268M Recombinant Mouse Kif3b Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rhesus Macaque KIF3B-2406R Recombinant Rhesus monkey KIF3B Protein, His-tagged Mammalian Cell His
Rhesus Macaque KIF3B-2227R Recombinant Rhesus Macaque KIF3B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque KIF3B-2227R-B Recombinant Rhesus Macaque KIF3B Protein Pre-coupled Magnetic Beads HEK293
Zebrafish KIF3B-5883Z Recombinant Zebrafish KIF3B Mammalian Cell His
Chicken KIF3B-2058C Recombinant Chicken KIF3B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KIF3B Related Articles
  • KIF3B Related Gene Family

KIF3B involved in several pathways and played different roles in them. We selected most pathways KIF3B participated on our site, such as Adaptive Immune System, Assembly of the primary cilium, Factors involved in megakaryocyte development and platelet production, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF3B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemBLMH;SIGLEC5;STIM1B;SIGLEC7;UBR2;NCR3LG1;AHCYL1;TREML1;B2ML
Assembly of the primary ciliumDYNLL2B;TUBG1;IFT122;ARL13B;TTBK2;CCT3;RPGRIP1L;KIF3B;CENPJ
Factors involved in megakaryocyte development and platelet productionHBBE1.1;GATA6;KLC3;CABLES1;BA1;DOCK1;EHD1;CBX5;GATA1
HemostasisANXA2A;MAFGB;MAFG;ZFPM2A;IGF2B;SCG3;AKAP1B;S100A10;HMG20B
Immune SystemCLEC4A;OASL;IFIT8;IFI16;EGR1;LILRA3;LAIR1;TRIM22;GBP2
Intraflagellar transportKIFAP3A;IFT80;DYNLRB1;FLR;DYF-1;HSPB11;KIF17;DYNLRB2;IFT74
KinesinsKIF22;KIF3B;KIF18A;KIFC1;KIF26A;KLC3;KIF4A;KIF3C;KIF20A
MHC class II antigen presentationMGC174857;RACGAP1;DYNC1I1;OSBPL1A;MGC174155;KIF11;AP1S3A;DYNC1LI2;CTSLL

KIF3B has several biochemical functions, for example, ATP binding, ATP-dependent microtubule motor activity, plus-end-directed, Rho GTPase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF3B itself. We selected most functions KIF3B had, and list some proteins which have the same functions with KIF3B. You can find most of the proteins on our site.

Function Related Protein
ATP bindingACVR1L;GLULA;SMC6;ABCC3;PEX1;NADSYN1;MYO1C;HSP90AB1;ACSM2B
ATP-dependent microtubule motor activity, plus-end-directedKIF1C;KIF5C;KIF5AA;KIF3B;KIF17;KIF19;KIF11;KIF1B;KIF5B
Rho GTPase bindingRHOH;DAAM1B;ANTXR2A;DIAPH1;FMNL2;DAAM1;ARHGEF16;ARHGEF2;FLNA
microtubule bindingCETN1;KIF1B;MAP4;WHAMM;CEP57;HDAC6;CAMSAP1B;S100A8;GABARAPA
microtubule motor activityAPPBP2;KIF5AA;KIF23;KIF14;KLC2;KLC3;SMC3;DYNC1LI1;KIF9
protein bindingZNF212;HSD17B10;NMRK1;GRIN1;RARG;SOX-2;ATP7A;NEFL;FRG1

KIF3B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF3B here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF3B.

KIFAP3; ARHGEF10; LMO2; LMO4; Mphosph9; Hax1; Magoh; Sptlc2; KIF3A; Homer1

Qiu, DY; Cheng, SM; et al. Localization and loss-of-function implicates ciliary proteins in early, cytoplasmic roles in left-right asymmetry. DEVELOPMENTAL DYNAMICS 234:176-189(2005).
Baker, SA; Freeman, K; et al. IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia. JOURNAL OF BIOLOGICAL CHEMISTRY 278:34211-34218(2003).
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