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KIF5B

Official Full Name

kinesin family member 5B
Overview

Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.
Synonyms

KIF5B; kinesin family member 5B; KNS; KINH; KNS1; UKHC; HEL-S-61; kinesin-1 heavy chain; kinesin heavy chain; kinesin 1 (110-120kD); ubiquitous kinesin heavy chain; conventional kinesin heavy chain; epididymis secretory protein Li 61;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E. coli
E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	KIF5B-377H	Recombinant Human KIF5B, GST-tagged	E.coli	GST	662-782aa	$319 / 25ug
Human	KIF5B-30173H	Recombinant Human KIF5B protein, GST-tagged	E.coli	GST	Glu662-Leu782	Inquiry
Human	KIF5B-317H	Recombinant Human KIF5B protein, His-tagged	E. coli	His	662-782 aa	$319 / 25ug
Mouse	KIF5B-8648M	Recombinant Mouse KIF5B Protein	Mammalian Cell	His		Inquiry
Mouse	KIF5B-4820M	Recombinant Mouse KIF5B Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	KIF5B-4820M-B	Recombinant Mouse KIF5B Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	KIF5B-3259R	Recombinant Rat KIF5B Protein	Mammalian Cell	His		Inquiry
Rat	Kif5b-326R	Recombinant Rat Kif5b protein, His-tagged	E.coli	His	Ile9~Lys226	$298 / 10ug
Rat	KIF5B-2915R	Recombinant Rat KIF5B Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	Kif5b-262R	Recombinant Rat Kif5b Protein, His-tagged	E.coli	His	Ile9~Lys226	$298 / 10ug
Rat	KIF5B-2915R-B	Recombinant Rat KIF5B Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
KIF5B Related Articles
KIF5B Related Gene Family

KIF5B involved in several pathways and played different roles in them. We selected most pathways KIF5B participated on our site, such as Adaptive Immune System, Dopaminergic synapse, Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF5B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Adaptive Immune System	BLMH;KIF4A;THEM4;CXADR;CD96;DYNLL2;TRIM9;AGO2;RAPGEF3
Dopaminergic synapse	GNB3;PLCB3;ATF4;KCNJ9;PPP2R2D;PPP2R1B;GRIA2;MAPK10;GNAI3
Endocytosis	PSD;PIP5KL1;IL2RGB;TSG101;HSP70L;GRK7;AMPH;EHD1B;ADRBK2
Factors involved in megakaryocyte development and platelet production	RACGAP1;HBBE3;LRRC16A;MAFF;HMG20B;KIF3A;AKAP10;DOCK1;KLC3
Hemostasis	KIF18A;KIFC1;ABHD6B;SERPINA1L;CEACAM6;CFHL3;VPS45;ABHD12;ANXA2B
Immune System	RAET1E;PPAPDC1B;TRIM14;EDARADD;ASB13;PVRL2L;WIPF2;LILRB3;DEFB116
Insulin Signaling	RRAD;MAPK4;RHOJ;MAPK6;SGK2;MYO1C;KIF5B;MAP3K10;ARHGAP33
Insulin processing	KIF5A;CPN1;PCSK1;SLC30A5;KIF5B;EXOC5;CPE;PCSK2;SLC30A6

KIF5B has several biochemical functions, for example, ATP binding, ATP-dependent microtubule motor activity, plus-end-directed, microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF5B itself. We selected most functions KIF5B had, and list some proteins which have the same functions with KIF5B. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	SMARCA2;NIM1;OLA1;TTLL5;STK24A;DHX57;PRKAA1;KIF22;ACSL5
ATP-dependent microtubule motor activity, plus-end-directed	KIF19;KIF5B;KIF5C;KIF3A;KIF18B;KIF17;KIF1B;KIF18A;KIF5A
microtubule binding	CNN3;PSRC1;CETN2;MAP4;KIF18A;BIRC5;SERPINB1A;KIF2A;FAM83D
microtubule motor activity	KIFC2;DNAH14;PROL1;KIF2B;DYNC1H1;KLC1;SMC3;KIF12;KIFC1
protein binding	SLC9A7;RARA;ATP6V1E2;ATXN3;PPP1CB;CLEC1B;HTR1E;CABP1;ZNF580

KIF5B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF5B here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF5B.

YWHAZ; YWHAQ; YWHAB; YWHAG; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; BCAR3; VDAC1; NME2; SFN; VHL; RANBP2; Hap1

Hutarew, G; Hauser-Kronberger, C; et al. Immunohistochemistry as a screening tool for ALK rearrangement in NSCLC: evaluation of five different ALK antibody clones and ALK FISH. HISTOPATHOLOGY 65:398-407(2014).

Go, H; Jung, YJ; et al. Diagnostic method for the detection of KIF5B-RET transformation in lung adenocarcinoma. LUNG CANCER 82:44-50(2013).